PYRONE

作品数：18被引量：25H指数：3
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相关领域：理学医药卫生更多>>
相关作者：冯卫生郑晓珂朱继忠刘璇更多>>
相关机构：河南中医药大学长春中医药大学北京理工大学更多>>
相关期刊：《Chinese Journal of Structural Chemistry》《Journal of Chinese Pharmaceutical Sciences》《Marine Life Science & Technology》《药学学报》更多>>
相关基金：国家自然科学基金国家高技术研究发展计划河南省科技攻关计划更多>>
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Ocellatuspyrones A‒G,new antibacterial polypropionates from the Chinese mollusk Placobranchus ocellatus
《Marine Life Science & Technology》2023年第3期373-386,共14页Song-Wei Li Dan-Dan Yu Ming-Zhi Su Li-Gong Yao Hong Wang Xueting Liu Yue-Wei Guo 
This research work was fnancially supported by the National Key Research and Development Program of China(N0.2022YFC2804100);the Natural Science Foundation of China(No.81991521).We thank Prof.H.-Y.Zhang from Shanghai Institute of Materia Medica,CAS,for the neuroprotective efect tests and Prof.J.Li from Shanghai Institute of Materia Medica,CAS,for the PTP1B inhibitory activity and antiviral activity assays.We thank Dr.Christiane Waldrich for the taxonomic identifcation of the mollusk material.
Marine invertebrates serve as rich sources of secondary metabolites with intriguing chemical diversities and a wide spectrum of biological activities.Particularly,marine shell-less sacoglossan mollusks have attracted ...
关键词：Placobranchus ocellatus γ-pyrone polypropionate Photosynthetic mollusk Antibacterial activity 
Assessment on facile Diels-Alder approach of α-pyrone and terpenoquinone for the expedient synthesis of various natural scaffolds
《Natural Products and Bioprospecting》2022年第1期137-157,共21页Aluru Rammohan Albert F.Khasanov Dmitry S.Kopchuk Duvvuru Gunasekar Grigory V.Zyryanov Oleg N.Chupakhin 
Council on grants of the President of the Russian Federation, HШ-2700.2020.3, Zyryanov Grigory V., Российский Фонд Фундаментальных Исследований (РФФИ), Grant # 21-13-00304, Zyryanov Grigory V.
The development of highly facile synthetic procedures for the expedient synthesis of complex natural molecules is always in demand.As this aspect,the Diels-Alder reaction(DAR)has a versatile approach to the synthesis ...
关键词：α-Pyrone Diels-Alder reaction(DAR) Marine natural compounds Terpenoquinone Total synthesis 
怀中1号鲜地黄化学成分研究被引量：5
《药学学报》2021年第11期3097-3103,共7页范锡玲 刘晏灵 曹彦刚 任英杰 王梦娜 陈旭 何晨 郑晓珂 冯卫生 
国家重点研发计划:中医药现代化研究重点专项-地黄特色中药材产业链关键技术研究(2017YFC1702800);河南省重大科技专项:地黄、山药、牛膝豫产道地药材品质保障关键技术与品质特色研究(171100310500)。
采用Toyopreal HW-40C、Sephadex LH-20、硅胶和半制备液相等多种色谱学技术从怀中1号鲜地黄中分离得到20个化合物。根据理化性质与波谱数据鉴定其结构,分别为3-methyl-2-(hydroxymethyl)-4H-pyrone-4-one(1)、3-氨基-2-吡啶乙醇(2)、(5...
关键词：玄参科 鲜地黄 化学成分 3-methyl-2-(hydroxymethyl)-4H-pyrone-4-one 3-氨基-2-吡啶乙醇 (5’S)-2-oxo-N-phenylpyrrolidine-3-carboxamide 
Tetraketide α-pyrone reductases in sporopollenin synthesis pathway in Gerbera hybrida:diversification of the minor function
《Horticulture Research》2021年第1期2962-2973,共12页Lingping Zhu Teng Zhang Teemu H.Teeri 
The structurally robust biopolymer sporopollenin is the major constituent of the exine layer of pollen wall and plays a vital role in plant reproductive success.The sporopollenin precursors are synthesized through an ...
关键词：SYNTHESIS implies outside 
The [4+2] Cycloaddition of 2-Pyrone in Total Synthesis被引量：4
《Chinese Journal of Chemistry》2019年第9期946-976,共31页Quan Cai 
The National Natural Science Foundation of China (Grant No. 21801043), the "Z1000-Youth Talents Plan", and Fudan University (start-up gra nt) are ack no wledged for fi nan cial support.
Diels-Alder reaction is one of the most important reactions in organic synthesis and has witnessed great achievements in total syntheses of complex natural products.In this review,we will focus on the [4+2] cycloaddit...
关键词：CYCLOADDITION 2-Pyrone TOTAL SYNTHESIS 
α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells被引量：1
《Natural Products and Bioprospecting》2017年第4期329-334,共6页Rui-Min Yang Xiu-Lei Zhang Li Wang Jian-Ping Huang Jing Yang Yi-Jun Yan Jian-Ying Luo Xiang-Ting Wang Sheng-Xiong Huang 
the National Natural Science Foundation of China to S-X.H(No.81522044)and to X.W(No.31471226);High-end Science and Technology Talents Program of Yunnan Province to S-X.H(No.2013HA022);a Grant from the Thousand Youth Talents Program of China.
Tamoxifen resistance(TamR)is the underlying cause of treatment failure in many breast cancer patients receiving tamoxifen.In order to look for noncytotoxic natural products with the ability to reverse TamR,an extract ...
关键词：Breast cancer Tamoxifen resistance RESENSITIZATION a-Pyrone derivatives STREPTOMYCES 
Synthesis and Biological Activity of 6-methyl-4-hydroxy-2-pyrone Derivatives
《Plant Diseases and Pests》2014年第4期43-45,共3页Chi Jianguo Kong Xue Gao Yongchao Huang Yujie 
Supported by Research Award Fund for Outstanding Young Scientists in Shandong Province(BS2011NY015);Science and Technology Development Plan of Shandong Province(2011GNC11101);"Twelfth Five-Year"Key Technology R&D Program(2011BAE06B004-11)
With maleic acid as the raw material, 6-methyl-4-hydroxy-2-pyrone, 6-methyl-4-alkoxy-2-pyrone and 6-methyl-4-hydroxy-3-acyl-2-pyrone derivatives were obtained via loop closing, O-alkylation and acylation reaction, and...
关键词：PYRONE SYNTHESIS Antifungal activity 
Synthesis and biological evaluation of 3-amino-2-pyrones as selective cyclooxygenase-1(COX-1) inhibitors被引量：1
《Chinese Chemical Letters》2013年第2期120-122,共3页Xue-Ping Chu Qing-Fa Zhou Shen Zhao Fei-Fei Ge Mian Fu Jia-Peng Chen Tao Lu 
the National Natural Science Foundation of China(No. 21102179);Fundamental Research Funds for the Central Universities(No.JKZ2011011) for the financial support
Received 2 December 2012 Received in revised form 21 December 2012 Accepted 27 December 2012 Available online 4 February 2013
关键词：3-Amino-2-pyroneBiological activityCOX-l-selective inhibitorSynthesis 
Secondary metabolites from fungus Alternaria sp. CIB 108
《Chinese Chemical Letters》2011年第10期1226-1228,共3页Qian Feng Chen Min Zhou Tao Yang Xiao Zhen Chen Chun Wang Guo Lin Zhang Guo You Li 
supported financially by the NSFC(No.20902089 to G.Y.Li);the Knowledge Innovation Program of the Chinese Academy of Sciences(No.KSCX2-EW-G-13-04)
A new compound,3-butyryl-6-[rel-（1S,2S）-1,2-dihydroxypropyl]-4-hydroxy-2H-pyran-2-one（1）,was isolated from the solid fermented rice culture of Alternaria sp.CIB 108,along with three known ones,deoxyradicinin（2）,...
关键词：Altemaria FERMENTATION PYRONE 
A Cost-effective Approach for 2-（t-Butyl）-6-methyl-4H-pyrone-A Key Intermediate Toward the Synthesis of Red-emitting Dyes for OLED Applications被引量：3
《Chinese Journal of Chemistry》2006年第9期1137-1143,共7页姚宜山 啜玉涛 王雪松 邹德春 张宝文 
Project supported by the National Natural Science Foundation of China （Nos. 20272065 and 50125310）, 863 （No. 90101013）, 973 （Nos. 2002AA324080 and 2002CB613405） Program of China. Dedicated to Professor Xikui Jiang on the occasion of his 80th birthday.
In the interest of driving down the cost of DCM-type light emitting materials, we have found a new approach to prepare 2-（t-butyl）-6-methy1-4H-pyrone, which is cost effective and more amenable to large scale product...
关键词：2-（t-butyl）-6-methyl-4H-pyrone DCM-type dye red-emitting OLED 
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