CORONAVIRUSES

作品数：52被引量：111H指数：6
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Assessing the inhibition efficacy of clinical drugs against the main proteases of SARS-CoV-2 variants and other coronaviruses
《Quantitative Biology》2024年第3期324-328,共5页Wenlong Zhao Cecylia SLupala Shifeng Hou Shuxin Yang Ziqi Yan Shujie Liao Xuefei Li Nan Li 
National Key Research and Development Program of China,Grant/Award Number:2023YFA0913900;National Natural Science Foundation of China,Grant/Award Numbers:31971354,32100146,32170672,32271501。
The rapid evolution of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)mainly due to its high mutation rate and rapid viral replication,has led to new variants resistant to the available vaccines and monocl...
关键词：drug resistance enzymatic activity main protease SARS-CoV-2 
Distinctive serotypes of SARS-related coronaviruses defined by convalescent sera from unvaccinated individuals被引量：4
《hLife》2023年第1期26-34,共9页Chee Wah Tan Feng Zhu Wan Ni Chia #Barnaby EYoung Aileen Ying Yan Yeoh Thomas Althaus Chee Fu Yung Wee Chee Yap Beng Lee Lim Mark I-C Chen Jinyan Zhang Yun Yan Mah Eric Voiglio Alex Sigal Jianxin Huo Shengli Xu Yee Joo Tan Kong-Peng Lam David Lye Lin-Fa Wang 
supported in part by grants from the National Medical Research Council(COVID19RF-001,COVID19RF-003,COVID19RF-0008,COVID19RF-0014,COVID19RF-0018,COVID19RF3-0060,MOH-000535/MOH-OFYIRG19nov-0002 and MOH-000505-02);SingHealth Duke-NUS Academic Medicine COVID-19 Rapid Response Research Grant(AM/COV001/2020);Collaborative Research Fund(C2103-20GF);Wellcome COVID-19 Grant on Understanding the Biological Significance SARS-CoV-2 Variants(226120/Z/22/Z);National Institute of Health NIAID(R01AI163118 and 5U01AI151797);National Public Health COVID Program of the Government of Monaco.
Multiple Omicron sub-lineages have emerged,with Omicron XBB and XBB.1.5 subvariants becoming the dominant variants globally at the time of this study.The key feature of new variants is their ability to escape humoral ...
关键词：SARS-CoV-2 SARS-CoV-1 SEROTYPE Omicron primary infection convalescent sera 
Seasonal coronaviruses and SARS-CoV-2:effects of preexisting immunity during the COVID-19 pandemic
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2022年第6期451-460,共10页Gang WANG Ze XIANG Wei WANG Zhi CHEN 
the National Science and Technology Major Project of China(No.2018ZX10302206-003);the Zhejiang Provincial Natural Science Foundation of China(No.LY16H160057);the Health Commission of Zhejiang Province(No.2016KYA162);the Zhejiang Provincial Science and Technology Project of Traditional Chinese Medicine of China(No.2015ZA026)。
Although the coronavirus disease 2019(COVID-19)epidemic is still ongoing,vaccination rates are rising slowly and related treatments and drugs are being developed.At the same time,there is increasing evidence of preexi...
关键词：Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) Coronavirus disease 2019(COVID-19) Preexisting immunity Seasonal coronaviruses Vaccine 
The high diversity of SARS-CoV-2-related coronaviruses in pangolins alerts potential ecological risks被引量：3
《Zoological Research》2021年第6期834-844,共11页Min-Sheng Peng Jian-Bo Li Zheng-Fei Cai Hang Liu Xiaolu Tang Ruochen Ying Jia-Nan Zhang Jia-Jun Tao Ting-Ting Yin Tao Zhang Jing-Yang Hu Ru-Nian Wu Zhong-Yin Zhou Zhi-Gang Zhang Li Yu Yong-Gang Yao Zheng-Li Shi Xue-Mei Lu Jian Lu Ya-Ping Zhang 
This work was supported by the National Key Research and Development Projects of the Ministry of Science and Technology of China,National Key Research and Development Program of China(2021YFC0863300);Ministry of Agriculture of China(2016ZX08009003-006);Key Program of Chinese Academy of Sciences(KJZD-SW-L11);Animal Branch of the Germplasm Bank of Wild Species,Chinese Academy of Sciences(the Large Research Infrastructure Funding)。
Understanding the zoonotic origin and evolution history of SARS-CoV-2 will provide critical insights for alerting and preventing future outbreaks.A significant gap remains for the possible role of pangolins as a reser...
关键词：SARS-CoV-2 PANGOLIN Recombination DIVERSITY SEQUENCING MTDNA 
Coronaviruses in pregnant women in Saudi Arabia:A systematic comparative review of MERS-CoV and SARS-CoV-2
《Asian pacific Journal of Reproduction》2021年第3期97-101,共5页Mazin Barry Magdoleen A.Barry 
Objective:To compare the effects of coronaviruses,such as Middle East respiratory syndrome coronavirus(MERS-CoV)or coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2...
关键词：MERS-CoV SARS-CoV-2 COVID-19 Pregnant women 
Convalescent plasma as a therapeutic agent for SARS-CoV, MERS-CoV and SARS-CoV-2: A scoping review
《Journal of Acute Disease》2021年第2期47-56,共10页Abeba Haile Mariamenatu Emebet Mohammed Abdu 
Severe acute respiratory syndrome coronavirus(SARS-CoV),Middle East respiratory syndrome coronavirus(MERS-CoV),and SARS-CoV-2 are three kinds of coronaviruses that are exceptionally pathogenic to humans via zoonotic i...
关键词：Convalescent plasma CORONAVIRUSES SARS-COV MERS-CoV SARS-CoV-2 COVID-19 
Digestive system involvement of infections with SARS-CoV-2 and other coronaviruses:Clinical manifestations and potential mechanisms被引量：3
《World Journal of Gastroenterology》2021年第7期561-575,共15页Gao-Feng Zhan Yue Wang Ning Yang Ai-Lin Luo Shi-Yong Li 
Although coronavirus(CoV)infection is often characterized by respiratory symptoms,the virus can also result in extrapulmonary symptoms,especially the symptoms related to the digestive system.The outbreak of coronaviru...
关键词：SARS-CoV-2 Gastrointestinal diseases Liver dysfunction COVID-19 CORONAVIRUS MECHANISMS 
COVID-19: An overview and a clinical update被引量：5
《World Journal of Clinical Cases》2021年第1期8-23,共16页Arunkumar Krishnan James P Hamilton Saleh A Alqahtani Tinsay A Woreta 
The outbreak of coronavirus disease-2019(COVID-19,previously known as 2019 nCoV)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection in Wuhan City,China,has spread rapidly around the world.Mo...
关键词：CORONAVIRUSES COVID-19 SARS-CoV-2 EPIDEMIOLOGY SYMPTOMS Laboratory Imaging Treatment Vaccines PREVENTION 
SARS-CoV-2:A critical review of its history,pathogenesis,transmission,diagnosis and treatment被引量：1
《Biosafety and Health》2020年第4期217-225,共9页Mohd Sharjeel Sofi Aadil Hamid Sami Ullah Bhat 
The outbreak of the deadly virus(novel coronavirus or Severe Acute Respiratory Syndrome Coronavirus-2)that emerged in December 2019,remained a controversial subject of intense speculations regarding its origin,became ...
关键词：CORONAVIRUSES RNA viruses SARS-CoV-2 COVID-19 Biocidal agents 
The use of SARS-CoV-2-related coronaviruses from bats and pangolins to polarize mutations in SARS-Cov-2被引量：5
《Science China(Life Sciences)》2020年第10期1608-1611,共4页Tao Li Xiaolu Tang Changcheng Wu Xinmin Yao Yirong Wang Xuemei Lu Jian Lu 
Supported by grants from the National Natural Science Foundation of China(U1902201);the CAS Light of West China Program to X.L,and from the National Natural Science Foundation of China(91731301)to J.L.
Dear Editor,The coronavirus disease 2019(COVID-19)caused by the SARS-CoV-2 coronavirus has become a global pandemic.The SARS-CoV-2 genome has a similarity of 96.2%to that of RaTG13,a bat SARS-CoV-2-related coronavirus...
关键词：al. SIMILARITY operations 
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