CYTOTOXITY

作品数:10被引量:25H指数:4
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相关领域:医药卫生理学更多>>
相关期刊:《Neural Regeneration Research》《Chinese Journal of Structural Chemistry》《Chinese Journal of Biomedical Engineering(English Edition)》《Chinese Journal of Cancer Research》更多>>
相关基金:国家自然科学基金湖北省自然科学基金更多>>
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Synthesis and Absolute Configuration of((2R,3R,6S)-3-Hydroxy-6-(naphthalen-2-ylthio)-3,6-dihydro-2H-pyran-2-yl)methyl Pivalate
《Chinese Journal of Structural Chemistry》2021年第9期1238-1245,1112,共9页JIAO Yang ZHANG Jia-Ding WANG Shu-Zhang YAO Hui LIU Ming-Guo HUANG Nian-Yu 
the National Natural Science Foundation of China(No.82003621);Natural Science Foundation of Hubei Province(2020CFB205);Educational Commission of Hubei Province(Q20201204)。
A stereo-selective palladium-catalyzed one-pot Tsuji-Trost reaction was used to prepare fourβ-thiogalactosides from unsaturated D-galactal and thiol.Their structures were characterized by nuclear magnetic resonance s...
关键词:X-ray diffraction crystal structure absolute configuration β-thiogalactoside CYTOTOXITY 
Synthesis and Absolute Configuration of(2R,3S,4Z,6Z)-1,3-bis(benzyloxy)-8-chloro-7-((E)-(2-(2,4-dinitrophenyl)hydrazono)methyl)octa-4,6-dien-2-ol
《Chinese Journal of Structural Chemistry》2020年第10期1781-1787,1742,共8页ABDULMAJED OTHMAN Karwan CAI Jin-Jin XIE Rui ZHOU Xin-Ran YAO Hui HUANG Nian-Yu 
the National Natural Science Foundation of China(No.21602123);Youth Talent Development Foundation of China Three Gorges University。
Lewis acid-catalyzed[1,3]-sigmatropic O→C rearrangement was used to synthesize C-glycosides derivatives.The structure of the target compound was characterized by NMR and HR-ESI-MS,and its absolute configuration was c...
关键词:X-ray diffraction crystal structure absolute configuration conjugated aliphatic imine CYTOTOXITY 
Cytotoxic effect of methanolic extracts of Fritillaria imperialis bulbs and Eryngium caucasicum leaves on hepatoma and colon cancer cells被引量:4
《Asian Pacific Journal of Tropical Biomedicine》2019年第8期353-358,共6页Mostafa Kardan Zahra Yazdani Zaher Morsaljahan Mohammad Ali Ebrahimzadeh Alireza Rafiei 
supported by deputy of Research and Technology,Mazandaran University of Medical Sciences
Objective: To evaluate antitumor activities of Fritillaria imperialis and Eryngium caucasicum methanolic extracts on human hepatoma (HepG2) and colon cancer (HCT116) cell lines in comparison to human foreskin fibrobla...
关键词:FRITILLARIA imperialis ERYNGIUM caucasicum CYTOTOXITY Colon CANCER HEPATOMA CANCER 
Dried Rehmannia root protects against glutamate-induced cytotoxity to PC12 cells through energy metabolism-related pathways被引量:1
《Neural Regeneration Research》2017年第8期1338-1346,共9页Yong Liu Lei Liu Xi-xiang Ying Wen-juan Wei Chao Han Yang Liu Chun-hui Han Ai-jing Leng Jing-yun Ma Jing Liu 
supported by the National Natural Science Foundation of China,No.81471308,81271412;the Natural Science Foundation of Liaoning Province of China,No.2014023052;the Dalian Science and Technology Project Foundation of China,No.2015SF11GH094
Rehmannia has been shown to be clinically effective in treating neurodegenerative diseases; however, the neuroprotective mechanisms remain unclear. In this study, we established a model of neurodegenerative disease us...
关键词:nerve regeneration Rehmannia water extracts GLUTAMATE PC12 cells autophagy energy metabolism neural regeneration 
A new unconventional HLA-A2-restricted epitope from HBV core protein elicits antiviral cytotoxic T lymphocytes被引量:7
《Protein & Cell》2014年第4期317-327,共11页Lu Sun Yu Zhang Bao Zhao Mengmeng Deng Jun Liu Xin Li Junwei Hou Mingming Gui Shuijun Zhang Xiaodong Li George F. Gao Songdong Meng 
Cytotoxic T cells (CTLs) play a key role in the control of Hepatitis B virus (HBV) infection and viral clearance. However, most of identified CTL epitopes are derived from HBV of genotypes A and D, and few have be...
关键词:chronic hepatitis B HLA-A2 HBc peptideCTL response antiviral cytotoxity 
Azalomycin F_(4a) 2-ethylpentyl ester,a new macrocyclic lactone,from mangrove actinomycete Streptomyces sp.211726被引量:6
《Chinese Chemical Letters》2010年第8期947-950,共4页Gan Jun Yuan Kui Hong Hai Peng Lin Jia Li 
supported by The National High Technology Development Project(863)(No. 2007AA09Z415);The National Natural Science Foundation of China(No.U0633008)
Azalomycin F4a 2-ethylpentyl ester,a new 36-membered macrocyclic lactone antibiotic,was isolated from mangrove actinomycete Streptomyces sp.211726.Its structure was elucidated on the basis of spectroscopic data.The co...
关键词:Streptomyces sp.211726 Azalomycin F4a 2-ethylpentyl ester Antifungal activity CYTOTOXITY 
A new bibenzyl derivative from Pleione bulbocodioides被引量:6
《Chinese Chemical Letters》2008年第5期559-561,共3页Xin Qiao Liu Qiao Yu Yuan Yuan Qiang Guo 
A new bibenzyl derivative 1, named 2-(4''-hydroxybenzy1)-3-(3'-hydroxyphenethy1)-5-methoxy-cyclohexa-2,5-diene-1,4- dione, and two known stilbenoids (2, 3) were isolated from the tubers of Pleione bulbocodioi...
关键词:Pleione bulbocodioides BIBENZYL STILBENOIDS CYTOTOXITY 
A new phenanthro [2,3-b] furan from Pleione bulbocodioides被引量:3
《Chinese Chemical Letters》2007年第9期1089-1091,共3页Xin Qiao Liu Wen Yuan Gao Yuan Qiang Guo Tie Jun Zhang Lu Lu Yan 
A novel phenanthro [2,3-b] furan 1, named (3-hydroxy-9-(4′-hydroxy-3′-methoxyphenyl)-11-methoxy-5,6,9,10-tetrahydrophenanthro [2,3-b] furan-10-yl) methyl acetate, and two known phenolic compounds were isolated from ...
关键词:Pleione bulbocodioides Phenanthro [2 3-b] furan Phenolic compounds CYTOTOXITY 
GENETICALLY MODIFIED DENDRITIC CELLS INDUCED SPECIFIC CYTOTOXITY AGAINST HUMAN HCC CELLS IN VITRO
《Chinese Journal of Cancer Research》2004年第4期246-250,共5页刘彬彬 叶胜龙 贺平 郑宁 赵燕 孙瑞霞 刘银坤 汤钊猷 
This work was supported by NationalNatural Science Foundation of China (No. 39770826) andpartly by CMB (No. 93583).
Objective: to transduce the tumor associated antigen gene MAGE-1 and/or IL-12 gene into dendritic cells (DC) and to observe the in vitro cytotoxic effect induced by the genetically modified DC against the human hepato...
关键词:MAGE-1 IL-12 Dendritic cells Tumor vaccine GENETHERAPY Hepatocellular carcinoma 
Evaluation of the cell cytotoxity of biomaterials in vitro by using the ^( 125)I-UdR-release-test
《Chinese Journal of Biomedical Engineering(English Edition)》2002年第3期113-118,共6页LU Xiao-ying~1,XUE Miao~2,XU Shu-qing~2 
The ~ 125 I-UdR-release method is used for evaluation of the cytotoxity of biomaterials. In this method, K562 cells cultured in suspending were used to make a direct contact with materials. The cytotoxity of 14 kinds ...
关键词:I-UdR-release method biomaterial CYTOTOXITY 
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