Aim Nicotinamide phosphoribosyltransferase (NAMPT), also an adipokine known as visfatin, acts via enzymatic activity to synthesize nicotinamide mononucleotide (NMN) and then maintain homeostasis of nicotinam- ide ...
Dear Editor, Recent discoveries suggest that N6-methyladenosine (m6A) modification, a prevalent internal modification in eukaryotic RNA, is an essential RNA regulatory mecha- nism. This modification is post-transcr...
Development of the use of favin and nicotinamide-adenine nucleotide fluorescence in monitoringthe redox state of the free mitochondrial NADH/NAD+couple in cels,tissues and organs isreviewed.A break-through was the ide...
Students Practice and Innovation Training Project of Jiangsu,China in 2011;Colleges’Distinctive Discipline Construction Funding Project of Jiangsu,China。
Objective:This article aims to discuss the distribution of KCNQ1 gene polymorphism in the Chinese Han population in the Huaihai region of China and the correlation between KCNQ1 gene polymorphism and incidence of type...
A putative chromate ion binding site was identified proximal to a rigidly bound FMN from electron densities in the crystal structure of the quinone reductase from Gluconacetobacter hansenii (Gh-ChrR) (3s2y.pdb). To cl...
TRICHOSANTHIN (TCS) is a type Ⅰ ribosome inactivating protein (RIP) with the N-glycosi-dase activity. It removes adenine (ADE) at position A4324 of 28SrRNA. The crystal struc-tural model and the activity of mutants s...
The interactions between ferric ion and various nucleotides are no doubt very important in the fate of iron in vivo, especially in the process of iron absorption and transportation, as well as to seek potential drugs ...