Photoenzymatic catalysis has become an emerging field in organic synthetic chemistry that provides eco-friendly alternatives to traditional methods. This comprehensive review examines the developing field of photoenzy...
supported by the National Natural Science Foundation of China(22231011,22221002,22031006,21831008,22271192,92256301,92256303,91956116);the NSFC Distinguished Young Scholars(22225107);the Major Program of the Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences(ZYFZFX-9)。
Enzymes are the core for biological transformations in nature.Their structures and functions have drawn enormous attention from biologists as well as chemists since last century.The large demand of bioactive molecules...
This work is supported in part by grants from the National Key Research and Development Program(Nos.2018Y F A0900402 and 2016Y F A0501302);from the National Natural Science Foundation of China(Nos.21822703 and 21921003);from the MOST Inter-Government International Science and Technology Innovation Cooperation project(No.2019YFE0121100).
Main observation and conclusion The aminoglycoside antibiotic apramycin contains a unique bicyclic octose moiety,and biosynthesis of this moiety involves an oxidoreductase AprQ.Unlike other known“Q”series proteins i...
Diabetic retinopathy is one of the most serious complications of diabetes, which is also one of the most important causes of blindness around the world. Autofluorescence of flavin protein in retinal pigment epithelial...
A putative chromate ion binding site was identified proximal to a rigidly bound FMN from electron densities in the crystal structure of the quinone reductase from Gluconacetobacter hansenii (Gh-ChrR) (3s2y.pdb). To cl...
Optogenetics is an emerging field that combines optical and genetic approaches to non-invasively interfere with cellular events with exquisite spatiotemporal control. Although it arose originally from neuroscience, op...
This work was supported by the grants from the National NaturalScience Foundation of China (No. 39900008) and Natural Science Foun-dation of Guangdong Province (No. 990693)
The dependence of glycolate oxidase apoprotein (apoGO) activity on flavin analogs was surveyed in 9 higher plants from 7 families. Activities of all apoGOs depended not only on flavin mono- nucleotide (FMN) but also...
This work was supported by the National Natural Science Foundation of China(Grant No.30000036);Special Fund for Doctoral Program fromthe Ministry of Education of China and Foundation of University of Science and Technology of China.
Utilizing a pulse radiolysis equipment with time-resolved optical detector, kinetic processes of electron-induced splitting of cis-syn 1,3-dimethyluracil cyclobutane dimer (DMUD) in aqueous solution were investigated ...
The mechanism of cerium ions scavenging superoxide radical(O÷2) has been studied. The results show that (1) Ce^3+ can reduce O÷2 to H_2O_2 while it is oxidized to Ce^4+; (2) Ce^4+ can oxidize O÷2 to O_2 while it is...