BACKGROUND Multiple acyl-CoA dehydrogenase deficiency(MADD)is a disease of rare autosomal recessive disorder.There are three types of MADD.Type I is a neonatalonset form with congenital anomalies.Type II is a neonatal...
supported by the National Natural Science Foundation of China(No.22077113);Zhejiang Provincial Basic Public Welfare Research Project(No.GF21H300005).
Flavoproteins are proteins that contain a nucleic acid derivative of riboflavin:flavin adenine dinucleotide(FAD)or flavin mononucleotide(FMN).Flavoproteins are involved in a wide array of biological processes,such as ...
Supported by the National Natural Science Foundation of China,No.81971943,No.81772196,No.31470264,No.81271820,No.30870789,and No.30300117;the Stanley Foundation of United States,No.06R-1366(for Zhu F);the Medical Science Advancement Program(Basic Medical Sciences)of Wuhan University,No.TFJC 2018002.
BACKGROUND Schizophrenia afflicts 1%of the world population.Clinical studies suggest that schizophrenia patients may have an imbalance of mitochondrial energy metabolism via inhibition of mitochondrial complex I activ...
This work is supported in part by grants from the National Key Research and Development Program(Nos.2018Y F A0900402 and 2016Y F A0501302);from the National Natural Science Foundation of China(Nos.21822703 and 21921003);from the MOST Inter-Government International Science and Technology Innovation Cooperation project(No.2019YFE0121100).
Main observation and conclusion The aminoglycoside antibiotic apramycin contains a unique bicyclic octose moiety,and biosynthesis of this moiety involves an oxidoreductase AprQ.Unlike other known“Q”series proteins i...
a grant from the National Natural Science Foundation of China (No.81460199).
Background:Late-onset multiple acyl-coA dehydrogenase deficiency (MADD) is an autosomal recessive inherited metabolic disorder. It is still unclear about the muscle magnetic resonance image (MRI) pattern of the distal...
The relationship between the levels of renalase and changes in proteinuria, hypertension, renal function, renal tubular epithelial cell apoptosis and B-cell lymphoma-2 (Bcl-2) expression was investigated in patients...
grants from the National Natural Science Foundation of China,the National Key Clinical Specialty Discipline Construction Program,and Fujian Key Clinical Specialty Discipline Construction Program
Background: Lipid storage myopathy (LSM) is a genetically heterogeneous group with variable clinical phenotypes. Late-onset multiple acyl-coenzyme A dehydrogenation deficiency (MADD) is a rather common form of LS...
This work was supported by the Major Research plan of the National Natural Science Foundation of China (Grant No.91442201);the China Postdoctoral Science Foundation funded project (Grant No.2015M572148,2012M521430 and 2013T60721);the Open Research Fund of State Key Laboratory of Bioelectronics,Southeast University.
Photodynamic therapy(PDT)gains wide attention as a useful therapeutic method for cancer.It is mediated by the oxygen and photosensitizer under the specific light irradiation to produce the reactive oxygen species(ROS)...
Development of the use of favin and nicotinamide-adenine nucleotide fluorescence in monitoringthe redox state of the free mitochondrial NADH/NAD+couple in cels,tissues and organs isreviewed.A break-through was the ide...