PROCOLLAGEN

作品数:34被引量:274H指数:9
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相关领域:医药卫生更多>>
相关作者:金哲虎南美兰金承龙张季郝敏更多>>
相关机构:延边大学医学院附属医院上海上药华宇药业有限公司南京中医药大学更多>>
相关期刊:《Hepatobiliary & Pancreatic Diseases International》《Chinese Medical Journal》《实用医学杂志》《Journal of Biosciences and Medicines》更多>>
相关基金:国家自然科学基金中国博士后科学基金江苏省高校自然科学研究项目国家中医药管理局度中医药行业科研专项更多>>
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Threshold-Effect Associations of Serum 25- hydroxyvitamin D on Bone Turnover Markers and GC rs2282679 Variants in Chinese Women of Childbearing Age
《Biomedical and Environmental Sciences》2025年第4期433-446,共14页Xiaoyun Shan Yuting Li Xiayu Zhao Yichun Hu Siran Li Huidi Zhang Yang Cao Rui Wang Lichen Yang 
Objective This study aimed to investigate possible serum 25-hydroxyvitamin D[25(OH)D]cutoffs for the associations between 25(OH)D and Bone turnover markers(BTMs),and how GC gene variation influences such cutoffs in Ch...
关键词:25-hydroxyvitamin D OSTEOCALCIN Procollagen type 1 N-terminal propeptide β-CrossLaps of type 1 collagen containing cross-linked C-telopeptide Gene polymorphism 
Lentinula edodes extract inhibits matrix metalloproteinase expression and increases typeⅠprocollagen expression via the p38 MAPK/c-Fos signaling pathway in ultraviolet A and B-irradiated HaCaT keratinocytes被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2021年第4期164-173,共10页Jung Im Lee Jung Hwan Oh Fatih Karadeniz So Young Park Hye Ran Kim Hyun Jin Jo Kyung Im Jung Byung-Jin Jeon Chang-Suk Kong 
supported by the Ministry of Trade,Industry&Energy,Korea Institute for Advancement of Technology and Busan Institute For Regional Program Evaluation through the Encouragement Program for the Social and Economic Innovation Growth(project number,P0008724)
Objective:To determine the effect of Lentinula edodes extract on ultraviolet(UV)A and UVB-induced changes in matrix metalloproteinase(MMP)and type I procollagen expression using human immortalized HaCaT keratinocytes....
关键词:Lentinula edodes Ultraviolet Matrix metalloproteinases TypeⅠprocollagen Ha Ca T 
Age-Related Changes of Procollagen Alpha Polypeptide in Vascular Remodeling in Rat Vascular Smooth Muscle Cell
《Journal of Biosciences and Medicines》2020年第12期20-31,共12页Minmin Yu Haocheng Zhan Dalin Song Weili Gai 
The current study revealed that increased synthesis and secretion of collagen types I and III play major roles in arterial wall remodeling, aneurysm formation, and atherosclerotic cap stability. The aim is to investig...
关键词:AGE-RELATED Vascular Smooth Muscle Cell Procollagen Alpha Polypeptide Vascular Remodeling 
4-羟苯基维胺对瘢痕疙瘩成纤维细胞Procollagen Ⅰ和MMP-1 mRNA表达的影响被引量:3
《实用医学杂志》2018年第19期3172-3175,共4页南美兰 金玟言 金哲虎 金承龙 
国家自然科学基金项目(编号:81260233);吉林省科技厅自然科学基金项目(编号:20160101183JC);延边大学科技计划项目青年科研基金项目[编号:(2015)第31号]
目的探讨4-羟苯基维胺(4-HPR)对瘢痕疙瘩成纤维细胞Ⅰ型前胶原(ProcollagenⅠ)和基质金属蛋白酶-1(MMP-1)mRNA表达的影响。方法运用实时荧光定量PCR方法测定瘢痕疙瘩成纤维细胞中ProcollagenⅠ和MMP-1 mRNA表达情况。观察4-HPR对Procoll...
关键词:瘢痕疙瘩 4-羟苯基维胺 Ⅰ型前胶原 基质金属蛋白酶-1 
4-HPR对瘢痕疙瘩成纤维细胞Procollagen Ⅰ、MMP-1及信号通路PI3K/Akt的影响被引量:8
《中国皮肤性病学杂志》2018年第3期245-251,共7页南美兰 金哲虎 金承龙 
吉林省科技厅(20160101183JC);青年科研基金(2015)第31号;国家自然科学基金(81260233)
目的探讨4-羟苯基维胺(4-hydroxyphenyl-retinamide,4-HPR)对瘢痕疙瘩成纤维细胞的作用及PI3K/Akt信号转导通路的影响。方法通过免疫印迹方法检测人瘢痕疙瘩成纤维细胞中,4-HPR对Ⅰ型前胶原(type I pro-collagen,ProcollagenⅠ)和基质...
关键词:P13K/AKT信号通路 4-羟苯基维胺 Ⅰ型前胶原 瘢痕疙瘩 
生、醋莪术对大鼠免疫性肝纤维化及HSC-T6增殖和α-SMA,Procollagen Ⅰ表达的影响被引量:21
《中国中药杂志》2017年第13期2538-2545,共8页张季 宋嬿 王巧晗 李林 季德 顾薇 郝敏 陆兔林 毛春芹 
国家自然科学基金项目(81473349;81673598;81503249);中国博士后科学基金项目(2016M591893);江苏省高校自然科学研究重大项目(15KJA360005);国家中医药行业专项(2015468002-2);国家发改委中药饮片标准化建设(ZYBZH-Y-SC-40);国家中医药管理局全国中药特色技术传承人才培训项目(2015481601003)
比较生、醋莪术对猪血清所致大鼠免疫性肝纤维化及对活化的肝星状细胞(HSC-T6)增殖和α-SMA,ProcollagenⅠ表达的影响。采用腹腔注射猪血清0.5 mL/只,每周2次,共14周制备大鼠免疫性肝纤维化模型。观察生、醋莪术(0.95,1.90 g·kg^(-1))...
关键词:莪术 醋莪术 肝纤维化 肝星状细胞 Real-time PCR Α-平滑肌肌动蛋白 ProcollagenⅠ 
Effects of Yishengukang decoction on expression of bone-specific alkaline phosphatase,carboxyterminal propeptide of typeⅠprocollagen,and carboxyterminal cross-linked telepeptide of typeⅠcollagen in malignant tumor patients with bone metastasis被引量:7
《Journal of Traditional Chinese Medicine》2017年第1期30-34,共5页Yin Yukun Feng Li Zhou Lei Li Jie Gao Yin Wang Ningjun Yu Jianhua Jiang Zhenglong He Shengqi Lu Dianrong Wang Fang Du Yanlin 
Wangjing Hospital,China Academy of Chinese Medical Sciences Program:Clinical Study on Improving the Life Quality of Cancer Patients by Nourishing Yin and Tonifying the Kidney(No.2007-01);Specific Science and Technology Improvement Project of Beijing Traditional Chinese Medical Science and Technology Development Fund:Clinical Study on Chinese Herbs of Bushen Huayu Combined with Hyperthermia in Treating Bone Metastatic Pain(No.KJTS2011-13);Beijing Science and Technology Program"the Capital of special":Clinical Study on Chinese Herbs of Fuzheng Jiedu Huayu in Treating Cancer Pain(Z141107002514045)
OBJECTIVE: To investigate the effect of Yishengukang decoction on the expression of the metabolic bone markers, bone-specific alkaline phosphatase(BAP), carboxyterminal propeptide of type Ⅰ procollagen(PICP), and car...
关键词:Malignant tumor Neoplasm metastasis Alkaline phosphatase Collagen type  
Effects of Biejia Ruangan Tablet(复方鳖甲软肝片)-Containing Serum on Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 Expression in Cultured Renal Interstitial Fibroblasts被引量:6
《Chinese Journal of Integrative Medicine》2015年第2期152-156,共5页周瑾 陈香美 刘述文 付博 洪权 王书娟 
Supported by the National Science Foundation of China(No.30130220 and No.30873345);National Natural Science Found for Innovative Research Groups Science Foundation of China(No.30121005)
Objective: To investigate the effects of Biejia Ruangan Tablet (复方鳖甲软肝片, BRT)- containing serum on the expression of matrix metalloproteinase (MMP-9) and tissue inhibitor of metalloproteinase (TIMP-1) in...
关键词:renal interstitial fibroblasts Biejia Ruangan Tablet type  and  procollagen matrix metalloproteinase -9 tissue inhibitor of metalloproteinase -1 
Influence of serum adiponectin level and SNP +45 polymorphism of adiponectin gene on myocardial fibrosis被引量:4
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2013年第8期721-728,共8页Cheng-jun YAN Su-mei LI Qiang XIAO Yan LIU Jian HOU Ai-fang CHEN Li-ping XIA Xiu-chang LI 
Project supported by the Natural Science Foundation of Shandong Province, China (No. ZR2012HL19);the Science and Technology Development Plan of Tai’an City, China (No. 20113096)
Adiponectin plays an important role in the development of hypertension, atherosclerosis, and cardio- myocyte hypertrophy, but very little was known about the influence of serum adiponectin or the adiponectin gene poly...
关键词:Hypertension Myocardial fibrosis Adiponectin gene Type-Ⅰ procollagen carboxyl end peptide (PICP) Type-Ⅲ procollagen ammonia cardinal extremity peptide (PIIINP) 
Neocollagenesis in Non-Invasive Aesthetic Treatments
《Journal of Cosmetics, Dermatological Sciences and Applications》2013年第1期1-5,共5页Ilja L. Kruglikov 
Dermal neocollagenesis is often assumed to be the main reason of visible skin improvement after different non-invasive and minimal invasive aesthetic treatments. However, the very slow dynamics of the mature collagen ...
关键词:Neocollagenesis AESTHETIC TREATMENTS PROCOLLAGEN MATURE Collagen TURNOVER 
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