DIACYLGLYCEROL

作品数：25被引量：43H指数：3
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相关领域：生物学医药卫生更多>>
相关作者：袁玉英石其贤张信岳陈文颖张玲珍更多>>
相关机构：浙江省医学科学院第二军医大学东南大学更多>>
相关期刊：《Chinese Herbal Medicines》《Oil Crop Science》《Grain & Oil Science and Technology》《Acta Pharmacologica Sinica》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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Hepatic CDP-diacylglycerol synthase 2 deficiency causes mitochondrial dysfunction and promotes rapid progression of NASH and fibrosis被引量：2
《Science Bulletin》2022年第3期299-314,共16页iesi Xu Siyu Chen Wei Wang Sin Man Lam Yang Xu Shaohua Zhang Huimin Pan Jingjing Liang Xiahe Huang Yu Wang Ting Li Yuqiang Jiang Yingchun Wang Mei Ding Guanghou Shui Hongyuan Yang Xun Huang 
the Ministry of Science and Technology of China(2018YFA0506902,2016YFA0500100,and 2018YFA081104);the National Natural Science Foundation of China(9195420001,31771305,and 31630019);Chinese Academy of Sciences(XDPB17)。
Nonalcoholic fatty liver disease(NAFLD)encompasses a spectrum of pathologies,ranging from steatosis to nonalcoholic steatohepatitis(NASH).The factors promoting the progression of steatosis to NASH are still unclear.Re...
关键词：NASH CDP-diacylglycerol synthase MITOCHONDRIA Mitochondria-associated membranes Phospholipid 
Diacylglycerol Compounds from Barks of Betula platyphylla with Inhibitory Activity against Acyltransferase被引量：8
《Chinese Herbal Medicines》2014年第2期164-167,共4页Nan Zhang Na Li Ya-nan Sun Jia-lin Li Shan-shan Xing Zhen-dong Tuo Long Cui 
Science and Technology Development Program of Jilin Province(201205099)
Objective To identify the active compounds from the barks of Betula platyphylla for inhibitory on diacylglycerol acyltransferase（DGAT1）.Methods Bioassay-guided fractionation resulted in the isolation of DGAT1 inhibi...
关键词：Betucaseae Betula platyphylla diacylglycerol acyltransferase1 lupane triterpenes 
Increased Seizure Susceptibility in a Mouse with Diacylglycerol Kinase <i>β</i>Deficiency被引量：1
《Neuroscience & Medicine》2013年第2期117-122,共6页Mitsue Ishisaka Kazuhiro Tsuruma Masamitsu Shimazawa Yasuhito Shirai Naoaki Saito Hideaki Hara 
Diacylglycerol kinase (DGK) is an enzyme that converts diacylglycerol to phosphatidic acid. Several DGK isoforms have been implicated in the pathogenesis of seizure, but the role of DGKβ in seizure is unknown. In the...
关键词：DIACYLGLYCEROL KINASE SEIZURE PARVALBUMIN 
Effect of CD40-CD40 ligand interaction on diacylglycerol-protein kinase C signal transduction pathway and intracellular calcium in cultured human monocytes
《Acta Pharmacologica Sinica》2003年第7期687-691,726,共6页严金川 吴宗贵 孔宪涛 仲人前 张玲珍 
Project supported by the National Basic Research Program of China (No G2000056903);Shanghai Medical Development(2000IZD002).
AIM: To investigate whether CD40-CD40 ligand interaction can activate diacylglycerol (DAG)-protein kinase C (PKC) signaling pathway and intracellular free calcium ([Ca^(2+)]_i) in cultured human peripheral blood monoc...
关键词：CD40 antigens CD40 ligand protein kinase C DIGLYCERIDES MONOCYTES signal transduction calcium 
Effect of protein kinase C on guinea pig sperm acrosome reaction induced by progesterone被引量：1
《Acta Pharmacologica Sinica》2000年第9期21-25,共5页陈文颖 袁玉英 石其贤 张信岳 
Project supported by the National Natural Science Foundation of China (No 39870364);Natural Science Foundation of Zhejiang Province (No 398028);National "9.5" Pan Deng Project.
AIM; To investigate the effect of protein kinase C (PKC) on the guinea pig sperm acrosome reaction (AR) induced by progesterone (P4). METHODS; Guinea pig spermatozoa were preincubated in MCM-Ca2+ DF medium at 38.5℃ u...
关键词：protein kinase C acrosome reaction PROGESTERONE phorbol 12 13-dibutyrate DIACYLGLYCEROL calcium SPERMATOZOA 
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