Research reported in this article was supported by the National Institute of General Medical Sciences of the National Institutes of Health under award number R01GM141374 and the National Science Foundation grants 2222157 and 2302424.
Lipid phosphorylation by diacylglycerol kinase(DGK)that produces phosphatidic acid(PA)plays important roles in various biological processes,including stress responses,but the underlying mechanisms remain elusive.Here,...
the Natural Science Foundation of China (31600059, 31425002, and 31741005), the Natural Science Foundation of Shandong, China (ZR2015CQ003 and ZR201709180185);the Biological Carbon Sequestration Program (ZDRW-ZS-2016-3) from the Chinese Academy of Sciences;the Chinese Key R&D Plan for Synthetic Biology Project.
The composition of polyun saturated fatty acids (PUFAs) in triacylglycerols (TAGs) is key to health ben efits and for oil applications, yet the underlying genetic mechanism remains poorly understood. In this study, by...
In Arabidopsis, three lipase-like regulators, SAG101, EDS1, and PAD4, act downstream of resistance protein-associated defense signaling. Although the roles of SAG101, EDS1, and PAD4 in biotic stress have been extensiv...
supported by a grant from the National High-Tech R&D Program of China (863 Program, N20080753)
The objective of the present study was to evaluate potential adverse effects of diacylglycerol microemulsion (DAGM) in rats/mice. Acute safety evaluation was carried out by giving intragastrically with 20 mL 25% DAG...
This work was supported by the National Natural Science Foundation of China (No 30400154 and 30400329), Innovation Research Team Program of Ministry of Education (No IRT0560), and the National Program of Basic Research of China (No G2006CB500808). Acknowledgement We thank Prof Yasuo MORI (University of Kyoto) for providing the plasmids of TRPC7 and mutCaM.
Aim: The aim of the present study was to explore the mechanism for the Ca^2+- dependent inactivation of the canonical transient receptor potential (TRPC) 7 channel expressed in human embryonic kidney 293 cells. Me...
This work was supported by the National Natural Science Foundation of China (Grant No. 39890390);the State Basic Research Development Plan of China (Grant No. G1998010100);the Innovative Foundation of Laboratory of Photosynthesis Basic Research, In
The influence of digalactosyldiacylglycerol (DGDG), one of the photosynthetic membrane lipids, on heat inactivation of the process of oxygen evolution has been studied in vitro in photosystem Ⅱ(PS Ⅱ) core complex. I...
Cells regulate phospholipase D (PLD) activity in response to numerous extracellular signals. Here, we investigated the involvement of PLD activity in transforming growth factor-β(TGF-β1)-mediated growth inhibition o...
Breakdown of phosphotidylinositol-4, 5-bisphosphate (PIP2) activates two distinct signal systems:production of inositol-1, 4, 5-trisphosphate (IP3) triggers release of calcium from intracellu...