supported by the National Natural Science Foundation of China (Grant Nos. 42072076, 42472070 & 41472058);the Second Tibetan Plateau Scientific Expedition and Research Program (STEP) (Grant No. 2019QZKK0801)。
The formation ages and genesis of the Nujiang Canyon ophiolites in the eastern Tibetan Plateau are still unclear, and it has been debated whether they belong to the Neo-Tethyan or Paleo-Tethyan suture zones. This stud...
After the disintegration of the Soviet Union,Russia regarded Eurasia as a“close neighbor”and a“special interest zone”,highlighted Eurasian countries in its foreign policy,and integrated the region through Commonwe...
supported by the National Natural Science Foundation of China(Grant Nos.82372705 and 31870748);the Shanghai Oriental Elite Project(Grant No.2000152009);the National Key R&D Program of China(Grant No.2017YFE0196300);the Shanghai Natural Science Foundation(Grant No.22ZR1466100);the Fundamental Research Funds for the Central Universities(Grant No.22120230292);the China Postdoctoral Science Foundation(Grant Nos.2023M742651 and GZC20231946);the Shuguang Project of Shanghai Municipal Education Commission and Shanghai Education Development Foundation(Grant No.17SG19);the Outstanding Yong Medical Scholar of Shanghai Municipal Commission of Health and Family Planning(Grant No.2017YQ067);the Outstanding Yong Scholar Grant of Tongji University(Grant No.PA2019000239);the Startup Funding of Frontier Science Research Center for Stem Cells&Shanghai East Hospital of Tongji University(Grant No.DFRC2019003),China.
Topologically associating domain(TAD)reorganization commonly occurs in the cell nucleus and contributes to gene activation and inhibition through the separation or fusion of adjacent TADs.However,functional genes impa...
funded by the National Science Foundation of China (32372910 and 32102567);the Program for Shaanxi Science&Technology (2022KJXX-13, 2023-YBNY-144, K3031223077 and 2022GD-TSLD-46–0302)
Background Fatty liver disease causes huge economic losses in the poultry industry due to its high occurrence and lethality rate.Three-dimensional(3D)chromatin architecture takes part in disease processing by regulati...
supported by the STI2030-Major Project(2021ZD0202503);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB39010700);the China Postdoctoral Science Foundation(2021M703089);the Fundamental Research Funds from the University of Science and Technology of China(WK9110000141).
Excitatory synapses serve as the primary sites for information transmission between neurons in the brain.Seminal work over the past decades has identified and revealed multiple compositions and functions of the synapt...
Project supported by the National Natural Science Foundation of China(No.61672080)。
Epigenetics’flexibility in terms of finer manipulation of genes renders unprecedented levels of refined and diverse evolutionary mechanisms possible.From the epigenetic perspective,the main limitations to improving t...
The diversified dispute resolution(DDR)in China is different from the alternative dispute resolution(ADR)in Western countries with respect to its fundamental cause and political,economic,social,and cultural background...
supported by the National Natural Science Foundation of China(92354301,32222022,32300569,and 92054104);R&D Program of Guangzhou National Laboratory(GZNL2023A03004);Key Research and Development Program,the Ministry of Science and Technology of China(2022YFC2303502 and 2021YFC2300204);the Natural Science Foundation of Shanghai(23ZR1470900);Youth Innovation Promotion Association,Chinese Academy of Sciences.
The dynamic remodeling of the cytoskeletal network of vimentin intermediate filaments supports various cellular functions,including cell morphology,elasticity,migration,organelle localization,and resistance against me...
supported by the National Natural Science Foundation of China(Nos.81874181,81902361,3213000192,and 91940305);the National Science and Technology Major Projects for“Major New Drug Innovation and Development”(No.2019ZX09301-158);the Shanghai Sailing Program(No.19YF1433000);the Open Project Program of State Key Laboratory of Oncogenes and Related Genes(No.KF2120).
Altered three-dimensional architecture of chromatin influences various genomic regulators and subsequent gene expression in human cancer.However,knowledge of the topological rearrangement of genomic hierarchical layer...
was supported by the National Key Research and Development Program of China(Nos.2020YFC2004300,2020YFC2004303 and 2020YFC2004302);the National Natural Science Foundation of China(Nos.32000980 and 82171533);the Guangdong Basic and Applied Basic Research Foundation(Nos.2022A1515140142,2019A1515110427 and 2020B1515120014);the Key Laboratory Program of Guangdong Higher Education Institutes(No.2020KSYS001)。
Hemiplegia after stroke has become a major cause of the world's high disabilities,and it is vital to enhance our understanding of post-stroke neuroplasticity to develop e±cient rehabilitation programs.This study aime...