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INDELS: 作品数：39被引量：75H指数：6; 导出分析报告; 相关领域：农业科学更多>>; 相关作者：陈国宏赵蕾常国斌李彩霞魏以梁更多>>; 相关机构：公安部物证鉴定中心扬州大学西北农林科技大学北京市公安局更多>>; 相关期刊：《Science China(Life Sciences)》《中国家禽》《中国科技成果》《植物遗传资源学报》更多>>; 相关基金：国家自然科学基金中央级公益性科研院所基本科研业务费专项江苏省“六大人才高峰”高层次人才项目国家科技支撑计划更多>>

Identification of long InDels through whole genome resequencing to fine map qIF05-1 for seed isoflavone content in soybean(Glycine max L. Merr.): 《Journal of Integrative Agriculture》2025年第1期85-100,共16页Jia Jia Huan Wang Ximeng Yang Bo Chen Ruqian Wei Qibin Ma Yanbo Cheng Hai Nian; supported by the China Agriculture Research System of MOF and MARA(CARS-04-PS12);the Research and Development Program in the Key-Areas of Guangdong Province,China(2020B020220008);the Guangdong Agricultural Research System,China(2023KJ136-03).; Soybean seed isoflavones are a type of secondary metabolites that can provide health and nutrition benefits for humans. In our previous study, a stable quantitative trait locus(QTL) qIF05-1 controlling the seed isofla...; 关键词：SOYBEAN seed isoflavone content whole genome re-sequencing long InDels fine map

Molecular mechanisms of DNA lesion and repair during antibody somatic hypermutation: 《Science China(Life Sciences)》2024年第11期2344-2353,共10页Qian Hao Jinfeng Li Leng-Siew Yeap; supported by the National Key Research and Development Program of China(2021YFA1301400);the National Natural Science Foundation of China(32370934);the Shanghai Jiao Tong University 2030 Initiative(2030-B23).; Antibody diversification is essential for an effective immune response,with somatic hypermutation(SHM)serving as a key molecular process in this adaptation.Activation-induced cytidine deaminase(AID)initiates SHM by in...; 关键词：somatic hypermutation(SHM) insertions and deletions(indels) AID base excision repair(BER) mismatch repair(MMR) translesion synthesis(TLS)polymerases

Research Progress of Genomic Variation in Psoriasis: 《International Journal of Dermatology and Venereology》2022年第4期207-212,共6页Liang-Dan Sun; As a typical representative of global complex diseases,psoriasis has attracted widespread attention because of its high heritability,heterogeneity,and incidence.Environmentally induced activation of the inflammatory-i...; 关键词：PSORIASIS genomic variation functional structural variation INDELS precision medicine

Identification and characterization of long-InDels through whole genome resequencing to facilitate fine-mapping of a QTL for plant height in soybean(Glycine max L.Merr.): 《Journal of Integrative Agriculture》2022年第7期1903-1912,共10页LIU Chen TIAN Yu LIU Zhang-xiong GU Yong-zhe ZHANG Bo LI Ying-hui NA Jie QIU Li-juan; supported by the National Key R&D Program of China(2016YFD0100201 and 2020YFE0202300);the Agricultural Science and Technology Innovation Program(ASTIP)of the Chinese Academy of Agricultural Sciences。; With the development of sequencing technology, insertions-deletions(InDels) have been increasingly reported to be involved in the genetic determination of agronomical traits. However, most studies have focused on the ...; 关键词：SOYBEAN plant height whole genome re-sequencing long-InDels QTL

Contribution of rare mutational outcomes to broadly neutralizing antibodies被引量：2: 《Acta Biochimica et Biophysica Sinica》2022年第6期820-827,共8页Anqi Feng Qian Hao Leng-Siew Yeap; the grants from the National Key R&D Program of China(Nos.,2020YFA0112900,2021YFA1301400);the National Natural Science Foundation of China(Nos.,31722020,81671634,81861138014);the China Postdoctoral Science Foundation(Nos.,2016M601613,BX201600107,to,Q.H.)。; Antibodies are important immune molecules that are elicited by B cells to protect our bodies during viral infections or vaccinations. In humans, the antibody repertoire is diversified by programmed DNA lesion processe...; 关键词：somatic hypermutation AID broadly neutralizing antibodies INDELS ong CDR H3

Genetic diversity and phylogenetic analysis of Chinese Han and Li ethnic populations from Hainan Island by 30 autosomal insertion/deletion polymorphisms被引量：1: 《Forensic Sciences Research》2022年第2期189-195,共7页Jing Liu Ziwei Ye Zheng Wang Xing Zou Guanglin He Mengge Wang Shouyu Wang Yiping Hou; This work was supported by the National Natural Science Foundation of China[grant numbers 81571854 and 81871532];the Open Project of Key Laboratory of Forensic Genetics in Ministry of Public Security[grant number 2017FGKFKT01];the Fundamental Research Funds for the Central University[grant number YJ201651].; With the characteristics of low mutation rate,length variation and short amplicon size,insertion/deletion polymorphisms(InDels)have the advantages of both short tandem repeats(STRs)and single nucleotide polymorphisms(...; 关键词：Forensic sciences forensic genetics INDELS Investigator DIPplex kit Hainan Han Hainan Li

基于家蚕中肠、脂肪体转录组数据的SNP/Indels位点分析被引量：1: 《江苏农业科学》2022年第3期9-15,共7页王晖高妍夏孙志超王敬李季生李娜黄露贾漫丽谢岩; 河北省自然科学基金青年基金(编号:C201806033);河北省高等学校科学技术研究项目(编号:BJ2018032);承德医学院高层次人才科研启动基金(编号:201604);河北省科技厅“技术创新引导专项-科技工作会商”。; 为了解家蚕转录组中SNP/Indel位点的分布及序列特征,采用转录组测序技术对2个品种彩4、东肥家蚕的中肠、脂肪体组织分别进行高通量测序,并对含有SNP/Indel位点的基因功能进行GO、KEGG注释。结果表明,家蚕中肠、脂肪体转录组数据质量合格...; 关键词：家蚕转录组单核苷酸多态性插入缺失分布规律

基于38-plex InDels的西北地区人群遗传推断研究: 《中国法医学杂志》2021年第5期488-492,共5页张博源赵慧王庆国董薇赵蕾江丽杨瑞琴韩俊萍; 国家自然科学基金面上项目(81772027)。; 目的基于38-plex InDels族群推断体系对中国西北地区新疆汉族、兰州汉族、兰州东乡族、兰州撒拉族、兰州裕固族5个族群的群体遗传结构和族群成分进行研究,评估该体系的推断效能。方法使用38-plex InDels体系检验西北地区5个族群共165份...; 关键词：法医遗传学 INDEL 族群推断

两种DNA族群推断技术在一组家系样本中的比较: 《中国法医学杂志》2021年第4期388-393,共6页王庆国江丽王文平张涛谢何鑫李唐松马原孙文平韩俊萍; 2017国家重点研发计划(2017YFC0803501);国家自然基金课题(81772027);中央级公益性科研院所基本科研业务费专项资金计划(2017JB026);2018首都科技领军人才培养工程支持(Z18110006318006)。; 目的使用课题组构建的27-plex SNPs和38-plex InDels两套族群推断体系,检测一组维族与回族通婚家系样本,通过两种体系间的相互印证,以获得更可靠的种族分析结果。方法分别利用两套检测体系,对来自一维族—回族通婚家系的三代成员共16份...; 关键词：法医遗传学族群推断 27-plex SNPs族群推断体系 38-plex InDels族群推断体系

LEPR基因InDel检测及其与同羊尾脂和生长性状关联分析被引量：3: 《农业生物技术学报》2021年第6期1142-1149,共8页易晓华刘世荣张宇潘赟袁婷婷孙秀柱; 农业农村部“农牧交错带牛羊牧繁农育关键技术集成示范项目”(16190050-10);陕西省重点研发计划(2018ZDXM-NY-040)。; 同羊是我国著名的肉毛兼用脂尾半细毛地方绵羊(Ovis aries)品种,脂肪组织是储存能量、为机体供应能量的器官,可分泌瘦素(leptin,LEP)、瘦素受体(leptin receptor,LEPR)和炎症因子等。脂肪细胞因子信号通路(adipocytokine)中LEP和LEPR基...; 关键词：瘦素受体(LEPR) 同羊插入/缺失(InDels) 尾脂生长性状

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