PERIODONTIUM

作品数：14被引量：114H指数：7
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Regulatory mechanisms and regeneration strategies of the soft-hard tissue interface in the human periodontium
《BMEMat(BioMedical Engineering Materials)》2024年第3期28-50,共23页Gao-peng Dang Yu Wei Qian-qian Wan Jun-ting Gu Kai-yan Wang Mei-chen Wan Chen-yu Wang Jing-han Song Zhao Mu Franklin R.Tay Li-na Niu 
Shaanxi Key Scientific and Technological Innovation Team of China,Grant/Award Number:2020TD-033;National Key Research and Development Program of China,Grant/Award Numbers:2022YFC2405900,2022YFC2405901;National Natural Science Foundation of China,Grant/Award Numbers:81870805,82325012;National Clinical Research Center for Oral Diseases of China,Grant/Award Number:LCA202004。
The soft-hard tissue interface of the human periodontium is responsible for periodontal homeostasis and is essential for normal oral activities.This softhard tissue interface is formed by the direct insertion of fibro...
关键词：interface tissue engineering oral health periodontal ligament soft-hard tissue interface tissue repair 
Development of a multicellular 3D-bioprinted microtissue model of human periodontal ligament-alveolar bone biointerface:Towards a pre-clinical model of periodontal diseases and personalized periodontal tissue engineering
《Genes & Diseases》2022年第4期1008-1023,共16页Murat Taner Vurat ŞükranŞeker Özge Lalegül-Ülker Mahmut Parmaksiz Ayşe Eser Elçin Yaşar Murat Elçin 
This work was partially supported by a grant from The Scientific and Technological Research Council of Turkey (TUBITAK;No. 117M281).
While periodontal (PD) disease is among principal causes of tooth loss worldwide, regulation of concomitant soft and mineralized PD tissues, and PD pathogenesis have not been completely clarified yet. Besides, relevan...
关键词：3D bioprinting Alveolar bone Microtissue model Organ-on-a-chip .Periodontal ligament Periodontal tissue engineering Periodontal-osteoblastic biointer face Periodontium-on-a-chip 
A hierarchical bilayer architecture for complex tissue regeneration被引量：4
《Bioactive Materials》2022年第4期93-106,共14页Min Yu Dan Luo Jing Qiao Jiusi Guo Danqing He Shanshan Jin Lin Tang Yu Wang Xin Shi Jing Mao Shengjie Cui Yu Fu Zixin Li Dawei Liu Ting Zhang Chi Zhang Zhou Li Yongsheng Zhou Yan Liu 
supported by the National Natural Science Foundations of China No.81871492(Y.L.),No.51902344(D.L.)and No.61875015(Z.L.);Ten-Thousand Talents Program QNBJ2019-2(Y.L.);Key R&D Plan of Ningxia Hui Autonomous Region No.2020BCG01001(Y.L.);National Key R&D Project from Minister of Science and Technology of China No.2016YFA0202703(D.L.).
Engineering a complete,physiologically functional,periodontal complex structure remains a great clinical challenge due to the highly hierarchical architecture of the periodontium and coordinated regulation of multiple...
关键词：Biomimetic design Biphasic scaffold Mineralized collagen Micropatterned arrays Periodontium regeneration 
Exosomes derived from 3D-cultured MSCs improve therapeutic effects in periodontitis and experimental colitis and restore the Th17 cell/Treg balance in inflamed periodontium被引量：16
《International Journal of Oral Science》2021年第4期448-462,共15页Yong Zhang Jiayao Chen Haijun Fu Shuhong Kuang Feng He Min Zhang Zongshan Shen Wei Qin Zhengmei Lin Shuheng Huang 
This work was supported by grants from the National Natural Science Foundation of China(Grant Nos.81873713,81700959 and 81873829);the International Cooperation Project of Science and Technology in Guangdong Province(Grant No.2016B050502008);the Natural Science Foundation of the Tibet Autonomous Region(XZ2019ZR-ZY64(Z)).
Although mesenchymal stem cell-derived exosomes(MSC-exos)have been shown to have therapeutic effects in experimental periodontitis,their drawbacks,such as low yield and limited efficacy,have hampered their clinical ap...
关键词：period culture injection 
The recent advances in scaffolds for integrated periodontal regeneration被引量：14
《Bioactive Materials》2021年第10期3328-3342,共15页Hyun Nyun Woo Young Joon Cho Solaiman Tarafder Chang H.Lee 
This manuscript was in part supported by National Institutes of Health grant 1R01DE029321-01A1 to C.H.L.
The periodontium is an integrated,functional unit of multiple tissues surrounding and supporting the tooth,including but not limited to cementum(CM),periodontal ligament(PDL)and alveolar bone(AB).Periodontal tissues c...
关键词：PERIODONTIUM PERIODONTITIS Bioactive scaffold Multi-phase scaffold Periodontal regeneration 
Biomechanical and biological responses of periodontium in orthodontic tooth movement:up-date in a new decade被引量：32
《International Journal of Oral Science》2021年第2期129-147,共19页Yuan Li Qi Zhan Minyue Bao Jianru Yi Yu Li 
the financial support from the National Natural Science Foundation of China(project No.31971247).
Nowadays,orthodontic treatment has become increasingly popular.However,the biological mechanisms of orthodontic tooth movement(OTM)have not been fully elucidated.We were aiming to summarize the evidences regarding the...
关键词：PERIOD PREVENTION INFLAMMATION 
The protective effect of tetrahedral framework nucleic acids on periodontium under inflammatory conditions被引量：8
《Bioactive Materials》2021年第6期1676-1688,共13页Mi Zhou Shaojingya Gao Xiaolin Zhang Tianxu Zhang Tao Zhang Taoran Tian Songhang Li Yunfeng Lin Xiaoxiao Cai 
This study was supported by National Key R&D Program of China(2019YFA0110600);National Natural Science Foundation of China(81970986,81771125).
Periodontitis is a common disease that causes periodontium defects and tooth loss.Controlling inflammation and tissue regeneration are two key strategies in the treatment of periodontitis.Tetrahedral framework nucleic...
关键词：tFNAs PERIODONTITIS Nanomaterials ANTI-INFLAMMATION DNA nanotechnology PDLSCs 
Decreased osteogenic activity and mineralization of alveolar bone cells from a patient with amelogenesis imperfecta and FAM83H 1261G>T mutation被引量：2
《Genes & Diseases》2019年第4期391-397,共7页Nunthawan Nowwarote Thanaphum Osathanon Kiattipan Kanjana Thanakorn Theerapanon Thantrira Porntaveetus Vorasuk Shotelersuk 
The study was supported by the Medical Genomics Cluster of Chulalongkorn University,Chulalongkorn Academic Advancement Into Its 2nd Century Project,Newton Fund,and Thailand Research Fund(RSA6280001,DPG6180001,RSA6180019).Nunthawan Nowwarote is supported by the Ratchadapisek Sompote Fund for Postdoctoral Fellowship,Chulalongkorn University.We thank Trakarn Sookthonglarng and Yuttupong Kunchanapruek for blood collection,Lawan Boonprakong and Anucharte Sirjunbarl for microscope services.
FAM83H mutations lead to autosomal dominant hypocalcified amelogenesis imperfecta(ADHCAI).However,the biological role of FAM83H remains unclear.The present study aimed to characterize the alveolar bone cells isolated ...
关键词：Autosomal dominant inheritance Enamel hypoplasia Hypocalcified enamel MINERALIZATION Osteogenic differentiation PERIODONTIUM 
Dental and periodontal phenotype in sclerostin knockout mice被引量：7
《International Journal of Oral Science》2014年第2期70-76,共7页Ulrike Kuchler Uwe Y Schwarze Toni Dobsak Patrick Heimel Dieter D Bosshardt Michaela Kneissel Reinhard Gruber 
The Department of Oral Surgery,Head Professor G Watzek,Bernhard Gottlieb Dental School,and the Medical University of Vienna financially supported the analysis
Sclerostin is a Wnt signalling antagonist that controls bone metabolism. Sclerostin is expressed by osteocytes and cementocytes; however, its role in the formation of dental structures remains unclear. Here, we analys...
关键词：alveolar bone micro-computed tomography mouse PERIODONTIUM SCLEROSTIN TOOTH 
Role of Topical Application of Growth Factors on Periodontal Repair
《Natural Science》2014年第5期351-361,共11页Athraa Yahya Al-Hijazi Abdul Karim Abed Ali Al-Mahammadawy 
Reconstruction of lost or injured periodontal tissues in such a way that both the original structures and their function are completely restored. Restoring of lost periodontal tissues involves a creation of new attach...
关键词：Vascular ENDOTHELIAL GROWTH FACTOR PERIODONTIUM Healing TRANSFORMING GROWTH FACTOR 
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