This work was supported by the National Natural Science Foundation of China(81770999 and 81670281);the Shanghai Municipal Commission of Science and Technology Research Project(18140900304,and 19140900902);the Big Data and Artificial Intelligence Project(2020DSJ07).
Sodium salicylate is an anti-inflammatory medication with a side-effect of tinnitus.Here,we used mouse cochlear cultures to explore the effects of salicylate treatment on cochlear inner hair cells(IHCs).We found that ...
supported by the National Natural Science Foundation of China(31071251 and 81471255);the National Basic Research Development Program of China(2014CB542202);the Basic Research Program of the Department of Education,Jiangsu Province,China(14KJA310004);a Natural Science Research Project of Nantong Science and Technology Bureau,Jiangsu Province,China(HS2013014);the Natural Science Research Project of Nantong University,Jiangsu Province,China(12Z045,13Z008)
Myelination by oligodendrocytes in the central nervous system requires coordinated exocytosis and endocytosis of the major myelin protein, proteolipid protein (PLP). Here, we demonstrated that a small GTPase, Rab27b...
supported by National Basic Research Development Program of China (No.2006CB705600);National Natural Science Foundation of China(No. 30700253;No. 30800355);the Scientific Research Foundation for the Returned Overseas Chinese Scholars, Ministry of Education, China (No. 2008101);Program of Changjiang scholar and innovative research team in University of China(No. IRT 0734)
Objective Presynaptic voltage-gated Ca^2+ channels mediate rapid Ca^2+ influx into the synaptic terminal which triggers synaptic vesicle exocytosis and neurotransmitter release. The FM 1-43 dye was firstly introduce...
supported by the National Basic Research Development Program of China(No.2006CB705600);the National Natural Science Foundation of China(No.30700253,No.30800355);Research Project of Tianjin Medical University(No.2006KY21);2008 Scien-tific Research Foundation for the Returned Overseas Chi-nese Scholars.
Down syndrome (DS) is the most common cause of cognitive impairment associated with a congenital chromosomal abnormality, trisomy of chromosome 21. Mental retardation and congenital heart defects are key features of...