BACKGROUND The peritumoral region possesses attributes that promote cancer growth and progression.However,the potential prognostic biomarkers in this region remain relatively underexplored in radiomics.AIM To investig...
Metabolic reprogramming is a key feature driving oncogenesis in cancers. Recent studies have revealed that protein metabolism is largely altered in gliomas facilitating its malignant growth. Urea is the end product of...
The study was reviewed and approved by the Second Hospital of Shandong University Institutional Review Board,IRB No.KYLL-2023LW044.
BACKGROUND Recently,vessels encapsulating tumor clusters(VETC)was considered as a distinct pattern of tumor vascularization which can primarily facilitate the entry of the whole tumor cluster into the bloodstream in a...
the Greater Bay Area Institute of Precision Medicine,No.KCH2310094;Shanghai Sailing Program,No.22YF1405000;Research Startup Fund of Huashan Hospital Fudan University,No.2021QD035;and Clinical Research Plan of SHDC,No.SHDC2020CR3020A.
BACKGROUND Hepatocellular carcinoma(HCC)is a major cause of cancer-related mortality worldwide.Transcatheter arterial chemoembolization(TACE)has been performed as a palliative treatment for patients with HCC.However,H...
BACKGROUND Sarcopenia is the loss of skeletal muscle mass(SMM)and is a sign of cancer cachexia.Patients with advanced renal cell carcinoma(RCC)may show cachexia.AIM To evaluate the amount of SMM in male clear cell RCC...
Introduction: Meningiomas are the most common type of extra-axial neoplasm. Peritumoral brain edema (PTBE) can be seen around meningiomas while it may be absent in others. Despite that Ki67 proliferative index has bee...
Background and purpose:There exist two major consensus guidelines for target delineation in glioblastoma(GBM).Namely the established radiation therapy oncology group(RTOG)and the recently redefined European society fo...
the grants from the National Key R&D Program of China (No.2017YFC0107600),the National Natural Science Foundation of China (No.81773225);the Scientific Research Grant from Shanghai Municipal Commission of Health and Family Planning(No.20134051),the Interdisciplinary program of shanghai Tong University(No.YG2017MS21).
Triple negative breast cancer (TNBC)is the most lethal one for all types of breast cancer.Though radiotherapy is an efficient treatment,long-term survival rate of TNBC patients is still suboptimal. Hyprofractionated r...
AIM To identify whether chitinase 3-like 1(CHI3 L1) serves as a suitable biomarker for the prognosis of esophageal squamous cell carcinoma(ESCC) and to analyze this protein's cellular source.METHODS An ELISA was condu...
Objective The aim of the study was to determine the morphological characteristics of lymphatic microvessels and the relationship between lymphatic microvessel density(LMVD) and clinical and pathological characteristic...