云南高校图书馆联盟文献共享服务平台- PYRIMIDINONE

PYRIMIDINONE: 作品数：17被引量：18H指数：3; 导出分析报告; 相关领域：理学更多>>; 相关作者：赵春常更多>>; 相关机构：阿根塔发明有限公司中国科学院更多>>; 相关期刊：《Science China Chemistry》《Chinese Journal of Polymer Science》《Chinese Journal of Structural Chemistry》《Science Bulletin》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>

A Macroporous Cryogel with Enhanced Mechanical Properties for Osteochondral Regeneration In vivo: 《Chinese Journal of Polymer Science》2023年第1期40-50,共11页Xin-Yu Wu Jun Yang Fang-Hui Wu Wang-Bei Cao Tong Zhou Zhao-Yi Wang Chen-Xi Tu Zhong-Ru Gou Lei Zhang Chang-You Gao; the Key research and development program of Zhejiang Province(No.2021C03113);the Natural Science Foundation of Zhejiang Province(No.LD21E030001).; The dense networks of conventional hydrogel hinder the efficient cell penetration and thus tissue regeneration.In this study,a macroporous cryogel with excellent mechanical properties was designed and fabricated throu...; 关键词：MACROPOROUS CRYOGEL Gelatin Ureido pyrimidinone Osteochondral regeneration

A New Discovery towards Novel Skeleton of Benzimidazole-Conjugated Pyrimidinones as Unique Effective Antibacterial Agents被引量：2: 《Chinese Journal of Chemistry》2022年第22期2642-2654,共13页Xi Yang Rasheed Syed Bo Fang Cheng-He Zhou; supported by grants from the National Natural Science Foundation of China(No.21971212);the Research Fellowship for International Young Scientists from International(Regional)-Cooperation and Exchange Program of China National Natural ScienceFoundation(No.81350110523);theKey Project of Innovation Research 2035Pilot Plan of Southwest University(SWU-XDZD22007).; A class of new potential antibacterial agents with distinctive pyrimidinone benzimidazole skeleton was developed through nucleophilic substitution and Biginelli reaction starting from urea,ethyl 4-chloroacetoacetate a...; 关键词：PYRIMIDINONE BENZIMIDAZOLE Antibacterial Resistance Membrane

Preparation and Characterization of Attractive Poly(amino acid)Hydrogels Based on 2-Ureido-4[1H]-pyrimidinone被引量：1: 《Chinese Journal of Polymer Science》2021年第3期327-336,I0006,共11页Zhen Shi Qi Wang Gui-Fei Li Yu-Feng Shou Hong-Jie Zong Shi-Feng Yan Kun-Xi Zhang Jing-Bo Yin; financially supported by the National Natural Science Foundation of China(No.51773113)。; Self-healing hydrogels with the shear-thinning property are novel injectable materials and are superior to traditional injectable hydrogels.The self-healing hydrogels based on 2-ureido-4[1 H]-pyrimidinone(UPy)have rec...; 关键词：2-Ureido-4[1H]-pyrimidinone(UPy) Poly(l-glutamic acid)(PLGA) Self-healable PHOTO-CROSSLINKING

Synthesis, Crystal Structure and Antitumor Activity of 3,3-(1,4-Phenylene)-bisfuro[3,2-d]pyrimidin-4(3H)-ones: 《Chinese Journal of Structural Chemistry》2019年第6期918-922,共5页HUANG Sheng-Tian HU Yang-Gen SONG Xin-Jian; supported by the fund of Hubei Cooperative Innovation Center(No.2011JH-2014CXTT07);the Key Project of Project of Hubei University of Medicine(No.2014CXZ-05); 3,3-（1,4-Phenylene）-bis(polysubstituted furo[3,2-d]pyrimidin-4（3 H）-ones 3 were synthesized from the starting material of functionalized iminophosphorane 1 by aza-Wittig reaction. All of the title compounds were c...; 关键词：furo[3 2-d]pyrimidinone SYNTHESIS crystal structure antitumor activity

Structure-based design,synthesis,and biological evaluation of novel pyrimidinone derivatives as PDE9 inhibitors被引量：4: 《Acta Pharmaceutica Sinica B》2018年第4期615-628,共14页Xu-Nian Wu Ya-Dan Huang Jin-Xuan Li Yan-Fa Yu Qian Zhou Chen Zhang Yinuo Wu Hai-Bin Luo; supported by the National Key R&D Program of China (2017YFB0202600);Natural Science Foundation of China (Nos. 81522041,81373258,21572279,81602955,and 21402243);Science Foundation of Guangdong Province (Nos. 2014A020210009,2016A030310144);The Fundamental Research Funds for the Central Universities (Sun Yat-Sen University,No. 17ykjc03 and 17ykpy20);Guangdong Province Higher Vocational Colleges & Schools Pearl River Scholar Funded Scheme (2016);Special Program for Applied Research on Super Computation of the NSFC-Guangdong Joint Fund (the second phase) under Grant No. U1501501 for providing the supercomputing service; The pathological processes of Alzheimer's disease and type 2 diabetes mellitus have been demonstrated to be linked together. Both PDE9 inhibitors and PPARγ agonists such as rosiglitazone exhibited remarkable preclini...; 关键词：PDE9 inhibitors Alzheimer’s disease Type 2 diabetes mellitus ROSIGLITAZONE Molecular docking Dynamics simulation

Efficient synthesis of pyrano[2,3-d]pyrimidinone and pyrido[2,3-d]pyrimidine derivatives in presence of novel basic ionic liquid catalyst被引量：1: 《Chinese Journal of Catalysis》2017年第7期1245-1251,共7页Omid Goli Jolodar Farhad Shirini Mohadeseh Seddighi; the University of Guilan Research Council for the partial support of this work; A basic ionic liquid, namely 1,1＇-（butane-1,4-diyl）bis（1,4-diazabicyclo [2.2.2]octan-1-ium） hydrox-ide, was prepared and characterized using Fourier-transform infrared spectroscopy, XH nuclear magnetic...; 关键词：Basic catalyst Multicomponent reaction Pyrimidine derivative GRINDING

An efficient method for the synthesis of thieno[3',2':2,3]pyrido-[4,5-d]-thiazolo[3,2-a]pyrimidinones: 《Chinese Chemical Letters》2017年第3期579-582,共4页Dao-Lin Wang Dong Wang Jin-Juan Xing Jian-Hua Qian; partially supported by innovation team project of Liaoning Province Education Department(No.2015001); An efficient method for the preparation of thieno[3＇,2＇：2,3]pyrido[4,5-d]thiazolo[3,2-a] pyrimidin-5-ones 5 is described. The key intermediate, 7-（3-amino-4-cyano-5-phenyl aminothieno-2-yl）-5H-thiazolo-[80_TD$IF]...; 关键词：Thiazolo[3 2-a]pyrimidinone Thienopyridothiazolo[3 2-a]pyrimidinone Thorpe–Ziegler isomerization Pictet–Spengler reaction

Bronsted acidic ionic liquid [C_3SO_3HDoim]HSO_4 catalyzed one-pot three-component Biginelli-type reaction: An efficient and solvent-free synthesis of pyrimidinone derivatives and its mechanistic study被引量：3: 《Chinese Chemical Letters》2016年第2期226-230,共5页Zhi-Lei Zhou Peng-Cheng Wang Ming Lu; A series of Bronsted acidic ionic liquids（ILs） were prepared and used for Biginelli-type condensation reaction among aromatic aldehydes, urea or thiourea and cyclopentanone. Through this reaction, the synthesis of v...; 关键词：Bronsted acidic ionic liquids Catalysis Biginelli-type reaction PYRIMIDINONE Organic synthesis Applied chemistry

Efficient Synthesis,Crystal Structure and Antibacterial Activity of Two Novel Thieno[2,3-d]pyrimidin-4(3H)-one Derivatives: 《Chinese Journal of Structural Chemistry》2015年第5期673-680,共8页LI Rong-Kun YANG Quan-Li HUANG Nian-Yu CHEN Hong LIU Ming-Guo; Supported by the National Natural Science Foundation of China(No.21102084);Natural Science Foundation(No.KJ2010B001);Scientific Research Innovation Foundation of Graduate School of China Three Gorges University(No.2011CX052); Two new thieno[2,3-d]pyrimidin-4（3H）-one derivatives,C24H22 Cl N3O2S（5a） and C25H25N3O2S（5b）,have been synthesized via a tandem aza-Wittig reaction.This tandem reaction has many attractive aspects such as easily...; 关键词：crystal structure thieno[2 3-d]pyrimidinone aza-Wittig reaction synthesis antibacterial activity

N-Heterocyclic Carbene-catalyzed Reactions of o-Aminonitriles with Carbonyl Compounds Approach to 2,3-Dihydroquinazolin-4(1H)-ones: 《Chinese Journal of Chemistry》2014年第9期865-870,共6页Hongxin Chai Jiarong Li Liupan Yang Mingxing Liu Deli Yang Qi Zhang Daxin Shi; Financial support from the International S&T Cooperation Program of China(No.2012DFR40240)is gratefully acknowledged.; A green,efficient and convenient N-heterocyclic carbene-catalyzed procedure for the synthesis of novel 2,3-dihydroquinazolin-4(1H)-one derivates via condensation of o-aminonitriles and various carbonyl compounds was d...; 关键词：quinazolin-4(1H)-one N-heterocyclic carbene CARBONYL o-aminonitrile fused pyrimidinone

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

PYRIMIDINONE

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

PYRIMIDINONE

检索结果分析

下载全文

用户登录

高级检索检索式检索