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相关机构：中国计量科学研究院威斯康星大学麦迪逊分校中国医学科学院中国协和医科大学中华人民共和国公安部更多>>
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Assessment of superior mesenteric vascular flow quantitation in children using four-dimensional flow magnetic resonance imaging:A feasibility study
《World Journal of Radiology》2025年第2期21-27,共7页Kantheera Leesmidt Parmede Vakil Sofia Verstraete Amanda R Liu Rachelle Durand Jesse Courtier 
BACKGROUND Four-dimensional(4D)flow magnetic resonance imaging(MRI)is used as a noninvasive modality for assessing hemodynamic information with neurovascular and body applications.The application of 4D flow MRI for as...
关键词：Four-dimensional flow magnetic resonance imaging Superior mesenteric artery Superior mesenteric vein Bowel disease Mesenteric vessel flow analysis 
Biases inα-synuclein immuno-quantitation:a core problem for basic and ancillary studies of Parkinson’s disease and multiple system atrophy
《Translational Neurodegeneration》2024年第1期874-878,共5页Florent Laferrière Ludivine Sabatier Stéphane Claverol Francesca De Giorgi François Ichas 
support from the French Agence Nationale de la Recherche(ANR),under grant ANR-22-CE16-0002(project ASAPS);supported by the Center of Excellence in Neurodegeneration(CoEN)Bordeaux Initiative for Neurodegenerative Disorders(BIND)reference CHUBX 2022/07,by the MSA Coalition Global Seed Grant reference MSAC-2022-12-005(project FibrilloScreen).
Parkinson’s disease(PD)and multiple system atrophy(MSA)are distinct neurodegenerative disorders sharing the accumulation of pathological alpha-synuclein(α-syn)amyloids in neurons or glial cells.Amyloidogenesis arise...
关键词：ATROPHY AMYLOID aggregation 
A Two-color Single-molecule Sequencing Platform and Its Clinical Applications
《Genomics, Proteomics & Bioinformatics》2024年第1期169-175,共7页Fang Chen Bin Liu Meirong Chen Zefei Jiang Zhiliang Zhou Ping Wu Meng Zhang Huan Jin Linsen Li Liuyan Lu Huan Shang Lei Liu Weiyue Chen Jianfeng Xu Ruitao Sun Guangming Wang Jiao Zheng Jifang Qi Bo Yang Lidong Zeng Yan Li Hui Lv Nannan Zhao Wen Wang Jinsen Cai Yongfeng Liu Weiwei Luo Juan Zhang Yanhua Zhang Jicai Fan Haitao Dan Xuesen He Wei Huang Lei Sun Qin Yan 
DNA sequencers have become increasingly important research and diagnostic tools over the past 20 years.In this study,we developed a single-molecule desktop sequencer,GenoCare 1600(GenoCare),which utilizes amplificatio...
关键词：GenoCare Single-molecule sequencing SARS-CoV-2 Microbial quantitation Variant detection 
A compact liquid chromatography-mass spectrometry instrument for the quantitation of immunosuppressants被引量：1
《Chinese Chemical Letters》2023年第4期469-473,共5页Hao Gu Guoxin Dai Siyu Liu Yanbing Zhai Qian Xu Hongqiang Wu Wei Xu 
supported by the National Key Research and Development Program of China (No. 2020YFF01014502);the National Natural Science of Foundation of China (Nos. 21922401,201827810)。
Liquid chromatography tandem mass spectrometry(LC-MS/MS) plays an important role in clinical diagnostics. Although LC-MS/MS is superior in terms of accurately quantifying molecules in complex matrices,instrument footp...
关键词：Mass spectrometry INSTRUMENTATION LC-MS IMMUNOSUPPRESSANTS 
Recursive Zero-COVID model and quantitation of control efforts of the Omicron epidemic in Jilin province
《Infectious Disease Modelling》2023年第1期11-26,共16页Xinmiao Rong Huidi Chu Liu Yang Shaosi Tan Chao Yang Pei Yuan Yi Tan Linhua Zhou Yawen Liu Qing Zhen Shishen Wang Meng Fan Huaiping Zhu 
the National Natural Science Foundation of China,China(12101157,12126206);Natural Science Foundation of Jilin Province,China(20210101482JC);Natural Science Foundation of Heilongjiang Province,China(LH2021A003).
Since the beginning of March 2022,the epidemic due to the Omicron variant has developed rapidly in Jilin Province.To figure out the key controlling factors and validate the model to show the success of the Zero-COVID ...
关键词：Omicron variant Recursive Zero-COVID Model Elimination of cases at the community level Basic reproduction number Control reproduction number Quantitation of control efforts 
LC-MS/MS method for the quantitation of serum tocilizumab in rheumatoid arthritis patients using rapid tryptic digestion without IgG purification被引量：1
《Journal of Pharmaceutical Analysis》2022年第6期852-859,共8页Takashi Mochizuki Kaito Shibata Takafumi Naito Kumiko Shimoyama Noriyoshi Ogawa Masato Maekawa Junichi Kawakami 
supported by the Japan Society for the Promotion of Science KAKENHI(Grant No.:JP19H00349).
The quantitation of serum tocilizumab using liquid chromatography tandem-mass spectrometry(LC-MS/MS)method has not been widely applied in clinical settings because of its time-consuming and costly sample pretreatments...
关键词：TOCILIZUMAB LC-MS/MS Immobilized trypsin IgG purification Proteomics Rheumatoid arthritis 
Development of a surface plasmon resonance biosensor for accurate and sensitive quantitation of small molecules in blood samples
《Journal of Pharmaceutical Analysis》2022年第6期929-936,共8页Minyu Qi Diya Lv Ying Zhang Dongyao Wang Xiaofei Chen Zhenyu Zhu Zhanying Hong Yifeng Chai Hai Zhang Yan Cao 
sponsored by the National Natural Science Foundation of China(Grant No.:82174092);Science and Technology Commission of Shanghai Municipality(Grant No.:21ZR1483000);Shanghai Pujiang Program(Grant No.:21PJD083).
Therapeutic drug monitoring(TDM)has played an important role in clinical medicine for precise dosing.Currently,chromatographic technology and immunoassay detection are widely used in TDM and have met most of the needs...
关键词：Surface plasmon resonance UPLC-UV CHLORAMPHENICOL Methodological verification 
Upconversion FRET quantitation:the role of donor photoexcitation mode and compositional architecture on the decay and intensity based responses被引量：3
《Light(Science & Applications)》2022年第10期2321-2334,共14页Agata Mkotulska Aleksandra Pilch-WrÓbel Satu Lahtinen Tero Soukka Artur Bednarkiewicz 
This researchwas funded in part by National Science Centre,Poland Grant No.2021/41/N/ST5/02753.Fo。
Lanthanide-doped colloidal nanoparticles capable of photon upconversion(UC)offer long luminescence lifetimes,narrowband absorption and emission spectra,and efficient anti-Stokes emission.These features are highly adva...
关键词：excitation DONOR DECAY 
Simple Quantitation of Flucytosine in Low Volume Serum Samples and Evaluation of Common Endogenous Interferences by HPLC-UV
《American Journal of Analytical Chemistry》2022年第9期289-299,共11页Abdul Rafiq Khan Ali Alothaim Waleed Tamimi Majid Alshaibani Souad Marwan Al Enazi Syed Muhammad Saad Khalid Mohammed Khan 
5-Fluorocytosine (5-FC) is used for the treatment of several infections. It is extremely important to monitor blood level concentration for maximum activity to avoid its side effects. A simple, faster, and more accura...
关键词：5-FLUOROCYTOSINE Serum Sample HPLC-UV Method Quantification Validation 
Validation of Two Real-Time PCR Approaches for the Relative Quantitation of Pork and Horse DNA in Food Samples被引量：1
《Food and Nutrition Sciences》2022年第4期387-403,共17页Malcolm Burns Gavin Nixon 
Two real-time PCR methods for the relative quantitation of DNA from meat species in food samples are described: these methods are applicable for horse in processed beef meat products, and pork in raw/processed beef me...
关键词：Food Authenticity Food Adulteration Meat Speciation Meat Quantitation Real-Time PCR 
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