云南高校图书馆联盟文献共享服务平台- TOCILIZUMAB

TOCILIZUMAB: 作品数：47被引量：164H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：张冬青苗平韩潇周道斌姚健更多>>; 相关机构：上海交通大学北京协和医院天津市儿童医院沈阳医学院沈洲医院更多>>; 相关期刊：《药学进展》《Cardiology Discovery》《World Journal of Clinical Cases》《Infectious Diseases of Poverty》更多>>; 相关基金：国家自然科学基金上海市自然科学基金更多>>

Systemic juvenile idiopathic arthritis–associated lung disease: A retrospective cohort study: 《World Journal of Clinical Pediatrics》2024年第1期73-83,共11页Konstantin E Belozerov Natalia M Solomatina Eugenia A Isupova Alla A Kuznetsova Mikhail M Kostik; Supported by the Ministry of Science and Higher Education of the Russian Federation,No.075-15-2022-301.; BACKGROUND Lung damage in systemic juvenile arthritis(sJIA)is one of the contemporary topics in pediatric rheumatology.Several previous studies showed the severe course and fatal outcomes in some patients.The informat...; 关键词：Systemic juvenile arthritis Interstitial lung disease CANAKINUMAB TOCILIZUMAB INTERLEUKIN-6 INTERLEUKIN-1

Cytokine storm and translating IL-6 biology into effective treatments for CoVID-19: 《Frontiers of Medicine》2023年第6期1080-1095,共16页Tiantian Li Dongsheng Wang Haiming Wei Xiaoling Xu; As of May 3,2023,the Coronavirus disease 2019(COVID-19)pandemic has resulted in more than 760 million confirmed cases and over 6.9 million deaths.Several patients have developed pneumonia,which can deteriorate into ac...; 关键词：SARS-CoV-2 COVID-19 cytokine storm INTERLEUKIN-6 TOCILIZUMAB

Differential Roles of Interleukin-6 in Severe Acute Respiratory Syndrome-Coronavirus-2 Infection and Cardiometabolic Diseases: 《Cardiology Discovery》2023年第3期166-182,共17页Jingjing Ren Xiao-Qi Wang Tetsushi Nakao Peter Libby Guo-Ping Shi; supported by the National Heart,Lung,and Blood Institute (HL151627 and HL157073 to Guo-Ping Shi,HL134892 and HL163099 to Peter Libby);the National Institute of Neurological Disorders and Stroke (AG063839 to Guo-Ping Shi).; Severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2)infection can lead to a cytokine storm,unleashed in part by pyroptosis of virus-infected macrophages and monocytes.Interleukin-6(IL-6)has emerged as a key par...; 关键词：INTERLEUKIN-6 SARS-CoV-2 COVID-19 Metabolic disease Cardiovascular disease TOCILIZUMAB Olamkicept

Tocilizumab下调NF-κB/JNK减轻急性肺、肾损伤的效果与对脓毒症小鼠模型存活率的影响: 《中文科技期刊数据库（全文版）医药卫生》2023年第9期93-96,共4页朱景法黄天宝颜才荣杨少东陈金图; 泉州市科技计划资助:2021N086S。; 研究分析Tocilizumab通过下调NF-κB/JNK减轻急性肺和肾损伤并提高脓毒症小鼠模型的存活率。方法本次研究选择同一实验室的48只雄性C57BL/6小鼠作为此次研究对象,随机分成两组,并运用盲肠扎穿孔法(CLP)建立脓毒血症动物模型,视为CLP组...; 关键词：TOCILIZUMAB NF-κB/JNK 急性肺和肾损伤脓毒症小鼠模型的存活率

Successful treatment of a case of COVID-19 pneumonia following kidney transplantation using paxlovid and tocilizumab: 《World Journal of Clinical Cases》2023年第25期6012-6018,共7页Qian Chen Yu-Lin Niu; Supported by Guiyang Science and Technology Program,No.2019-9-1-39.; BACKGROUND Since its initial detection in 2019,coronavirus disease 2019(COVID-19)pneumonia has rapidly spread throughout the world in a global pandemic.However,reports of COVID-19 pneumonia among patients following ki...; 关键词：Clinical research Kidney transplantation Coronavirus disease 2019 pneumonia Paxlovid TOCILIZUMAB Case report

Successful treatment of granulomatosis with polyangiitis using tocilizumab combined with glucocorticoids:A case report: 《World Journal of Clinical Cases》2023年第5期1144-1151,共8页Peng-Fang Tang Long-Chuan Xu Wen-Ting Hong Hong-Ying Shi; BACKGROUND Tocilizumab is a humanized monoclonal antibody against the interleukin-6(IL-6)receptor that is commonly used to treat large vessel vasculitis and antineutrophil cytoplasmic antibody-related small vessel vas...; 关键词：TOCILIZUMAB Granulomatosis with polyangiitis Antineutrophil cytoplasmic antibody Case report

Extreme Hyperferritinemia in a Filipino Male Patient with Adult Onset Still’s Disease: A Case Report: 《Open Journal of Rheumatology and Autoimmune Diseases》2022年第4期119-127,共9页Denise Joy Emmanuelle Lopez Karla Sofia Reyes Aileen U. Agbanlog; Background: Elevated serum ferritin is more commonly due to reactive causes such as infection, hepatic disorders, rheumatologic conditions, and malignancy than true iron overload. Extreme hyperferritinemia (>10,000 ng...; 关键词：Still’s Disease HYPERFERRITINEMIA AUTOIMMUNE TOCILIZUMAB Case Report

LC-MS/MS method for the quantitation of serum tocilizumab in rheumatoid arthritis patients using rapid tryptic digestion without IgG purification被引量：1: 《Journal of Pharmaceutical Analysis》2022年第6期852-859,共8页Takashi Mochizuki Kaito Shibata Takafumi Naito Kumiko Shimoyama Noriyoshi Ogawa Masato Maekawa Junichi Kawakami; supported by the Japan Society for the Promotion of Science KAKENHI(Grant No.:JP19H00349).; The quantitation of serum tocilizumab using liquid chromatography tandem-mass spectrometry(LC-MS/MS)method has not been widely applied in clinical settings because of its time-consuming and costly sample pretreatments...; 关键词：TOCILIZUMAB LC-MS/MS Immobilized trypsin IgG purification Proteomics Rheumatoid arthritis

Considerations for management of patients with diabetes mellitus and acute COVID-19: 《World Journal of Diabetes》2022年第10期802-808,共7页Efterpi Mougakou Maria Kyziroglou Alexandra Tsankof Evangelos Cholongitas Konstantinos Tziomalos; Diabetes mellitus(DM)is an independent risk factor for admission to intensive care unit and death in patients with coronavirus disease 2019(COVID-19).On the other hand,medications used in the management of COVID-19 ar...; 关键词：Diabetes mellitus COVID-19 INSULIN Antidiabetic agents DEXAMETHASONE TOCILIZUMAB Remdesivir

Tocilizumab in severe COVID-19-A randomized,double-blind,placebo-controlled trial: 《Infectious Medicine》2022年第2期88-94,共7页Muhammad Irfan Malik Sardar Al Fareed Zafar Fabiha Qayyum Muna Malik Muhammad Sohaib Asghar Muhammad Junaid Tahir Ammarah Arshad Fatima Khalil Hafiza Shafia Naz Mudassar Aslam Jodat Saleem Abdul Aziz Mustafa Usman Azhar Muhammad Naqash Zohaib Yousaf; was obtained from the research ethical committee of Lahore General Hospital,hav-ing approval number 00-144-20(ClinicalTrials.gov ID:NCT04560205)。; Background:The therapeutic effectiveness of interleukin-6 receptor inhibitor in critically ill hospitalized patients with coronavirus disease 2019(COVID-19)is uncertain.Methods:To evaluate the efficacy and safety of t...; 关键词：INFLAMMATORY INFECTIOUS IMMUNOSUPPRESSION COVID-19 Therapy Trial

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