DIHYDROARTEMISININ

作品数：52被引量：162H指数：6
导出分析报告
相关领域：医药卫生更多>>
相关作者：朱安远郭华珍李晓静钟杭景永奎更多>>
相关机构：北京金自天正智能控制股份有限公司中国康复研究中心中国药科大学教育部更多>>
相关期刊：《Science China(Life Sciences)》《Chinese Journal of Integrative Medicine》《Regenerative Biomaterials》《Chinese Journal of Natural Medicines》更多>>
相关基金：国家自然科学基金广东省自然科学基金中国博士后科学基金更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Mitochondria-targeted carrier-free nanoparticles based on dihydroartemisinin against hepatocellular carcinoma被引量：1
《Chinese Chemical Letters》2024年第10期329-333,共5页Zhiyu Yu Xiang Luo Cheng Zhang Xin Lu Xiaohui Li Pan Liao Zhongqiu Liu Rong Zhang Shengtao Wang Zhiqiang Yu Guochao Liao 
funded and supported by the Department of Science and Technology of Guangdong Province(No.2022B1111020005);Key Laboratory of Guangdong Provincial Food and Drug Administration(No.2021ZDB03);the 2020 Guangdong Provincial Science and Technology Innovation Strategy Special Fund(Guangdong-Hong Kong-Macao Joint Lab,No.2020B1212030006);Guangdong Province Universities and Colleges Pearl River Scholar Funded Scheme(No.Guochao Liao,2019);Guangdong Basic and Applied Basic Research Foundation(Nos.2020B1515130005,2022A1515110270,202201011563);The Bureau of Science and Technology of Guangzhou City(No.HMJH_(2)019000)。
Hepatocellular carcinoma is a common and fatal malignancy for which there is no effective systemic therapeutic strategy.Dihydroartemisinin(DHA),a derivative of artemisinin,has been shown to exert anti-tumor effects th...
关键词：Hepatocellular carcinoma Carrier-freenanoparticles DIHYDROARTEMISININ Mitochondria targeting Apoptosis 
MicroRNA-32-5p inhibits metastasis by directly targeting VPS4B and increases sensitivity to dihydroartemisinin in neuroblastoma
《Science of Traditional Chinese Medicine》2024年第3期202-213,共12页Lina Chen Hui Liu Zhongyuan Zheng Shuiqing Qu Yu Zhang Shuoqiu Deng Shuo Shena Tuo Liu Yue Dai Yu Li Honghua Cui Yujie Li 
supported by the Fundamental Research Funds for the Central PublicWelfare Research Institutes(grant ZZ13-YQ-100);the NationalNatural Science Foundation of China(grants 82274181 and 82141001);Innovation Fund of China Academy of Chinese Medical Sciences(grantsCI2021A05106,CI2021A04611,andZZ16-ND-10-01);Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences(CI2021B015,CI2023E001TS12).
Background:Neuroblastoma(NB)is a malignant pediatric tumor requiring new therapies.Accumulating evidence has confirmed that microRNAs play critical roles in NBmetastasis.Dihydroartemisinin(DHA)is capable of inhibiting...
关键词：Neuroblastoma metastasis MiR-32-5p DIHYDROARTEMISININ Vacuolar protein sorting 4B(VPS4B) 
Noscapine shows antimalarial activity against Plasmodium falciparum 3D7,its clinical isolate Pf140/SS,and Plasmodium berghei ANKA
《Asian Pacific Journal of Tropical Biomedicine》2024年第8期350-358,共9页Swaraj Kumar Babu Sameer Maharana Satyaranjan Chhatria Dibya Ranjan Sahoo Ashirbad Nanda Satish Kanhar Prativa KBehera Sanjib Mohanty Pradeep Kumar Naik Praveen Kishore Sahu 
Objective:To evaluate the antimalarial activity of noscapine against Plasmodium falciparum 3D7 strain(Pf3D7),its clinical isolate(Pf140/SS),and Plasmodium berghei ANKA(PbA).Methods:Using ring-stage survival assay,phen...
关键词：MALARIA Plasmodium falciparum Plasmodium berghei NOSCAPINE ANTIMALARIAL DIHYDROARTEMISININ CYTOTOXICITY Falcipain-2 
Histopathological Evaluation of the Cardiotoxicity of Dihydroartemisinin-Piperaquine on Male Albino Rats
《Journal of Biosciences and Medicines》2023年第12期69-76,共8页Ramson Chinemerem Achilefu Ugonma Kendra Jumbo Daniel Chukwudi Oti Christian Kelechi Agwaraonye Ozioma Pricilla Okezie Wendy Chidera Anyanwu 
Problem Statement: Malaria’s global impact necessitates effective treatments, like dihydroartemisinin-piperaquine (DHA/PQP), though safety concerns, notably drug-induced cardiotoxicity (DICT), persist. A knowledge ga...
关键词：Dihydroartemisinin-Piperaquine Histopathological Evaluation Cardiac Muscles Albino Rats 
Low-temperature photothermal-induced alkyl radical release facilitates dihydroartemisinin-triggered“valve-off”starvation therapy
《Asian Journal of Pharmaceutical Sciences》2023年第5期152-163,共12页Xiaomin Su Boshu Ouyang Yao Liu Yang Wang Ruizhe Xu Lili Niu Nannan Li Ce Xu Zanya Sun Huishu Guo Zhiqing Pang Xiangrong Yu 
Funding support was provided by the National Natural Science Foundation of China(grant no.82071915);the Guang Dong Basic and Applied Basic Research Foundation(grant no.2022A1515220015);the Zhuhai City Department of science and technology(grant no.2220004000131)
The high nutrient and energy demand of tumor cells compared to normal cells to sustain rapid proliferation offer a potentially auspicious avenue for implementing starvation therapy.However,conventional starvation ther...
关键词：Starvation therapy Alkyl radicals Hydrogel Ink Low-temperature photothermal 
一种兼具程序性缓释双氢青蒿素和Fe^(2+)自供应能力的智能纳米药物用于肿瘤协同治疗
《Science China Materials》2023年第10期4071-4078,共8页赵莹 王樱蕙 曹悦 周仕杰 刘洋 牛瑞 徐博 张松涛 王大广 宋术岩 张洪杰 
supported by the National Key Research and Development Program of China(2020YFA0712102);the National Natural Science Foundation of China(52022094,22020102003,and 52072142);the Program of Science and Technology Development Plan of Jilin Province of China(20210101111JC and 20230508071RC);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2019232)。
双氢青蒿素(DHA)作为一种新型的抗癌药物引起了全世界的广泛关注.然而,DHA的固有缺陷降低了其在血液系统中的运输效率,而肿瘤细胞中铁含量不足进一步导致疗效不佳.因此,构建一个可同时负载DHA和Fe^(3+)并在肿瘤微环境中特异性释放出DHA...
关键词：DIHYDROARTEMISININ self-supply Fe^(2+) Ca^(2+)overloading synergistic therapy 
Dihydroartemisinin ameliorates innate inflammatory response induced by Streptococcus suis-derived muramidase-released protein via inactivation of TLR4-dependent NF-kB signaling
《Journal of Pharmaceutical Analysis》2023年第10期1183-1194,共12页Yun Ji Kaiji Sun Ying Yang Zhenlong Wu 
supported by the National Key R&D Program of China(Grant Nos.:2022YFF1100104 and 2022YFF1100102);the National Natural Science Foundation of China(Grant Nos.:31625025,32172749,and 32202701);the 2115 Talent Development Program of China Agricultural University(Grant No.:00109016);the Zhengzhou 1125 Talent Program,China(Grant No.:2016XT016).
Muramidase-released protein(MRP)is now being recognized as a critical indicator of the virulence and pathogenicity of Streptococcus suis(S.suis).However,the identification of viable therapeutics for S.suis infection w...
关键词：DIHYDROARTEMISININ Inflammation Muramidase-released protein Streptococcus suis Toll-like receptor 4 
Dihydroartemisinin inhibits plasmid transfer in drug-resistant Escherichia coli via limiting energy supply
《Zoological Research》2023年第5期894-904,共11页Xue-Yang Wang Huang-Wei Song Tian Yi Ying-Bo Shen Chong-Shan Dai Cheng-Tao Sun De-Jun Liu Jian-Zhong Shen Cong-Ming Wu Yang Wang 
supported in part by grants from the Laboratory of Lingnan Modern Agriculture Project (NT2021006);National Key Research and Development Program of China (2022YFD1800400)。
Conjugative transfer of antibiotic resistance genes(ARGs)by plasmids is an important route for ARG dissemination.An increasing number of antibiotic and nonantibiotic compounds have been reported to aid the spread of A...
关键词：DIHYDROARTEMISININ PLASMID mcr-1 bla_(NDM-5) Conjugation inhibitors TCA cycle 
Dihydroartemisinin attenuates ischemia/reperfusion-induced renal tubular senescence by activating autophagy被引量：2
《Chinese Journal of Natural Medicines》2023年第9期682-693,共12页LIU Huiling HUANG Zhou JIANG Hong SU Ke SI Zilin WU Wenhui WANG Hanyu LI Dongxue TAN Ninghua ZHANG Zhihao 
the National Natural Science Foundation of China(No.81700559);the Natural Science Foundation of Hubei Province(No.2021CFB360);the Program for Jiangsu Province Innovative Research Team.
Acute kidney injury(AKI)is an important factor for the occurrence and development of CKD.The protective effect of dihydroartemisinin on AKI and and reported mechanism have not been reported.In this study,we used two a...
关键词：AKI DIHYDROARTEMISININ Renal tubular senescence Fibrosis AUTOPHAGY 
Dihydroartemisinin increased the abundance of Akkermansia muciniphila by YAP1 depression that sensitizes hepatocellular carcinoma to anti-PD-1 immunotherapy
《Frontiers of Medicine》2023年第4期729-746,共18页Zhiqin Zhang Xinli Shi Jingmin Ji Yinglin Guo Qing Peng Liyuan Hao Yu Xue Yiwei Liu Caige Li Junlan Lu Kun Yu 
the National Natural Science Foundation of China(No.81873112);Science and Technology Project of Hebei Education Department(No.ZD2022120)for the economic support.
The effect of anti-programmed cell death 1(anti-PD-1)immunotherapy is limited in patients with hepatocellular carcinoma(HCC).Yes-associated protein 1(YAP1)expression increased in liver tumor cells in early HCC,and Akk...
关键词：hepatocellular carcinoma YAP1 Akkermansia muciniphila anti-PD-1 DIHYDROARTEMISININ bile acid 
全选清除导出
共6页<123456>
检索报告 对象比较 聚类工具 使用帮助 返回顶部