PHOSPHATIDYLCHOLINES

作品数:8被引量:2H指数:1
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相关领域:医药卫生化学工程更多>>
相关作者:缪长虹孙波更多>>
相关机构:复旦大学更多>>
相关期刊:《Acta Pharmacologica Sinica》《Signal Transduction and Targeted Therapy》《American Journal of Molecular Biology》《Journal of Integrative Agriculture》更多>>
相关基金:国家自然科学基金更多>>
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AKT2^(S128)/CCTα^(S315/319/323)-positive cancer-associated fibroblasts (CAFs) mediate focal adhesion kinase (FAK) inhibitors resistance via secreting phosphatidylcholines (PCs)
《Signal Transduction and Targeted Therapy》2024年第2期782-796,共15页Jie Chen Lingyuan Zhang Yuheng Zhu Di Zhao Jing Zhang Yanmeng Zhu Jingyuan Pang Yuanfan Xiao Qingnan Wu Yan Wang Qimin Zhan 
supported by the National Natural Science Foundation of China(81988101,81830086,and 81972243);CAMS Innovation Fund for Medical Sciences(2019-I2M-5-081);Suzhou Top-Notch Talent Groups(ZXD2022003);Major Program of Shenzhen Bay Laboratory(S201101004);Guangdong Basic and Applied Basic Research Foundation(2019B030302012);the Fund of“San-ming”Project of Medicine in Shenzhen(No.SZSM201812088).
Abnormal metabolism is regarded as an oncogenic hallmark related to tumor progression and therapeutic resistance.Present study employed multi-omics,including phosphoproteomics,untargeted metabolomics and lipidomics,to...
关键词:CAFs metabolism RESISTANCE 
Rapid semi-quantification of triacylglycerols,phosphatidylcholines,and free fatty acids in the rice bran of one grain
《Journal of Integrative Agriculture》2018年第5期977-981,共5页Junko Nagamoto Ai Sawazaki Motonori Miyago Bungo Shirouchi Mitsukazu Sakata TONG Litao Toshihiro Kumamaru Masao Sato 
supported by the Ministry of Agriculture, Forestry and Fisheries, MAFF, Tokyo, Japan (27001B)
We developed a microplate assay method for determining the contents of triacylglycerols(TAGs), phosphatidylcholines(PCs), and free fatty acids(FFAs) in the rice bran of one grain using enzymatic reactions. In th...
关键词:rice bran triacylglycerols phosphatidylcholines free fatty acids surfactants 
Enhanced Ionization of Phosphatidylcholines during MALDI Mass Spectrometry Using DCTB as Matrix
《Chinese Journal of Chemistry》2012年第9期2091-2096,共6页张莹 陆豪杰 
Phosphatidylcholines (PCs) are the most abundant phospholipids constituents of the cellular membrane, which exhibit a variety of biological functions. The distinct critical roles in cellular function make their anal...
关键词:PHOSPHATIDYLCHOLINES MATRIX MALDI-MS DCTB 
Oxidized phospholipids modify plasminogen and apolipoprotein(a): Implications for vascular disease
《American Journal of Molecular Biology》2012年第2期110-112,共3页Angelo M. Scanu Diana M. Stafforini Celina Edelstein 
Whereas the close structural homology between human plasminogen and apolipoprotein(a) has been known for a number of years only recent studies have revealed that both proteins carry linked oxidized phospholipids that ...
关键词:PLASMINOGEN Apolipoprotein(a) Lipoprotein(a) OXIDIZED PHOSPHOLIPIDS OXIDIZED PHOSPHATIDYLCHOLINES 
Detection of Six Kinds of Antiphospholipid Antibodies in the Serum of Healthy Volunteers
《Chinese Medical Sciences Journal》2004年第2期149-149,共1页ZheGuo Yu-mingZhao Ya-kunWang SarabadaniRahim Hong-duoChen 
关键词:Adult Antibodies  Anticardiolipin Antibodies  Antiphospholipid AUTOANTIBODIES Female Humans Male Middle Aged Phosphatidic Acids PHOSPHATIDYLCHOLINES PHOSPHATIDYLETHANOLAMINES Phosphatidylinositols Phosphatidylserines Reference Values 
Study on the Aggregation and Deaggregation Behaviors of Phosphatidylcholines被引量:1
《Chinese Journal of Chemistry》2003年第7期731-738,共8页计国桢 龙亚秋 蒋锡夔 
National Natural Science Foundation of China(No.29392201).
Phosphatidylcholines and their analogs, the functional building block of the membrane, are recently found to mediate multiple physiological processes and exhibit a broad range of desirable pharmacological effects, whi...
关键词:PHOSPHATIDYLCHOLINE hydrophobic lipophilic interac-tions (HLI) AGGREGATION DEAGGREGATION 
Pharmacodynamics and pharmacokinetics of inhaled nitric oxide in dogs with septic acute respiratory distress syndrome被引量:1
《Acta Pharmacologica Sinica》2002年第3期278-284,共7页缪长虹 孙波 蒋豪 薛张纲 Robert LINDWALL 
Project supported in Part by grants from China Medical Board of New York (95-620). Shanghai Education and Development Foundation (95SG010). and Shanghai Bareau of Health (97BR023. 99ZY1001).
To evaluate pharmacodynamics and pharmaco-kinetics of inhaled nitric oxide (iNO) in dogs with acute respiratory distress syndrome (ARDS). METHODS; ARDS, induced after iv injection of endotoxin, was evidenced by reduct...
关键词:adult respiratory distress syndrome nitric oxide PHOSPHATIDYLCHOLINES pulmonary surfactants respiratory insufficiency respiratory therapy 
Kinetic studies on the aggregation behavior of phosphatidylcholines and their analogs
《Chinese Journal of Chemistry》1998年第3期250-257,共8页计国桢 龙亚秋 蒋锡夔 
Project supported by the National Natural Science Foundation of China.
Phosphatidylcholines (Ln's) and their neutral analogs 1,2-diacyl-sn-glycerol-3-phosphoric acid bromoethyl esters (Pn's) have been found to exhibit different aggregation behaviors brought about by hydrophobic-lipophili...
关键词:Kinetic probe PHOSPHATIDYLCHOLINE hydrophobic-lipophilic interactions aggregating tendency 
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