云南高校图书馆联盟文献共享服务平台- PHOSPHATIDYLCHOLINE

PHOSPHATIDYLCHOLINE: 作品数：43被引量：68H指数：4; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：赵南明毛海滨单际修许强阮翔更多>>; 相关机构：中国科学院植物研究所清华大学更多>>; 相关期刊：《Asian Journal of Pharmaceutical Sciences》《Journal of Traditional Chinese Medical Sciences》《Science Bulletin》《Agricultural Biotechnology》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划河北省自然科学基金国家教育部博士点基金更多>>

Dietary Lipid Intervention in the Prevention of Brain Aging: 《Engineering》2024年第6期128-137,共10页Wei Xiong Bing Fang Xiaoyu Wang Ming Zhang Min Du Jiazeng Sun Juan Chen Yixuan Li Changhao Sun Xingen Lei Xue Zhang Fazheng Ren; supported by the National Key Research and Development Program of China(2022YFD2101003);the 111 Project from the Ministry of Education of the People’s Republic of China(B18053).; As people live longer,the burden of aging-related brain diseases,especially dementia,is increasing.Brain aging increases the risk of cognitive impairment,which manifests as a progressive loss of neuron function caused...; 关键词：Brain aging Nutritional intervention PHOSPHOLIPIDS PHOSPHATIDYLCHOLINE PHOSPHATIDYLSERINE PLASMALOGEN

Phosphatidylcholine deficiency increases ferroptosis susceptibility in the Caenorhabditis elegans germline被引量：1: 《Journal of Genetics and Genomics》2023年第5期318-329,共12页Jinglin Zhu Wei Meng Sin Man Lam Guanghou Shui Xun Huang; supported by the National Natural Science Foundation of China and the Ministry of Science and Technology of China (32230044, 91954207, and 2018YFA0506902); Ferroptosis,a regulated and iron-dependent form of cell death characterized by peroxidation of membrane phospholipids,has tremendous potential for the therapy of human diseases.The causal link between phospholipid hom...; 关键词：PHOSPHATIDYLCHOLINE Ferroptosis SPIN-4 STERILITY LYSOSOME

The role of phosphatidylcholine 34:1 in the occurrence,development and treatment of ulcerative colitis被引量：2: 《Acta Pharmaceutica Sinica B》2023年第3期1231-1245,共15页Tengjie Yu Zhihao Zhou Shijia Liu Changjian Li Zhi-Wei Zhang Yong Zhang Wei Jin Keanqi Liu Shuying Mao Lei Zhu Lin Xie Guangji Wang Yan Liang; supported by the Jiangsu Natural Science Funds(BK20211224,China);the Natural Science Foundation of Hebei Province(Nos.H2021302001,H2020208022,H2020208025,C2021418001,H2021208006,China);the CAMS Innovation Fund for Medical Sciences(2021-I2M-5-011,China).; Lipid homeostasis is considered to be related to intestinal metabolic balance,while its role in the pathogenesis and treatment of ulcerative colitis(UC)remains largely unexplored.The present study aimed to identify th...; 关键词：Ulcerative colitis LIPIDOMICS PC34:1 METABONOMICS FUMARATE

Integrative phosphatidylcholine metabolism through phospholipase A_(2)in rats with chronic kidney disease被引量：1: 《Acta Pharmacologica Sinica》2023年第2期393-405,共13页Yan-ni Wang Zhi-hao Zhang Hong-jiao Liu Zhi-yuan Guo Liang Zou Ya-mei Zhang Ying-yong Zhao; supported by the National Natural Science Foundation of China(Nos.81703691,82074002);Shaanxi Key Science and Technology Plan Project(No.2019ZDLSF04-04-02);ShaanXi Science and Technology Innovation Team(No.2019TD-016).; Dysregulation in lipid metabolism is the leading cause of chronic kidney disease(CKD)and also the important risk factors for high morbidity and mortality.Although lipid abnormalities were identified in CKD,integral me...; 关键词：chronic kidney disease LIPIDOMICS phosphatidylcholine metabolism phospholipase A_(2) Rheum officinale

Less is more:seipin,phospholipids,and embryogenesis: 《Life Metabolism》2022年第2期99-100,共2页Bin Liang Jennifer L Watts; In a recent paper published in Life Metabolism,Zhu et al.revealed that mutations that reduce phosphatidylcholine(PC)synthesis rescue embryonic lethality but exacerbate lipid droplet(LD)abnormalities in C.elegans seipi...; 关键词：FORMATION synthesis PHOSPHATIDYLCHOLINE

Reduced phosphatidylcholine synthesis suppresses the embryonic lethality of seipin deficiency被引量：1: 《Life Metabolism》2022年第2期175-189,共15页Jinglin Zhu Sin Man Lam Leilei Yang Jingjing Liang Mei Ding Guanghou Shui Xun Huang; supported by the National Natural Science Foundation of China(9195420001);the Ministry of Science and Technology of China(2018YFA0506902).; Seipin plays a vital role in lipid droplet homeostasis,and its deficiency causes congenital generalized lipodystrophy type II in humans.It is not known whether the physiological defects are all caused by cellular lipi...; 关键词：seipin PHOSPHATIDYLCHOLINE EMBRYOGENESIS lipid droplet

Role of semi-purified andrographolide from Andrographis paniculata extract as nano-phytovesicular carrier for enhancing oral absorption and hypoglycemic activity被引量：1: 《Chinese Herbal Medicines》2020年第2期142-155,共14页Vinod Kumar Verma Md.Kamaruz Zaman Shekhar Verma Santosh Kumar Verma Khomendra Kumar Sarwa; financial support through UGC-JRF in Engineering and Technology(Vide-F No.10-01/2008 SA-I)。; Objective:Andrographis paniculata is a well-known medicinal plant in Southeast Asia,India and China.The plant contains andrographolide(AN),a very important phytochemical used in various health problems.However,AN is l...; 关键词：Andrographis paniculata(Burm.f.)Nees ANDROGRAPHOLIDE hypoglycemic activity liquid dispersion nano-phyto vesicle soya phosphatidylcholine

Enhanced water solubility, antioxidant activity, and oral absorption of hesperetin by D-α-tocopheryl polyethylene glycol 1000 succinate and phosphatidylcholine被引量：2: 《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2019年第3期273-281,共9页Su-fang GU Li-ying WANG Ying-jie TIAN Zhu-xian ZHOU Jian-bin TANG Xiang-rui LIU Hai-ping JIANG You-qing SHEN; Project supported by the National Natural Science Foundation of China(Nos.51773176,51522304,and U1501243);the Natural Science Foundation of Zhejiang Province(No.LY17H300002),China; Hesperetin,an abundant bioactive component of citrus fruits,is poorly water-soluble,resulting in low oral bioavailability.We developed new formulations to improve the water solubility,antioxidant activity,and oral abs...; 关键词：HESPERETIN D-α-Tocopheryl polyethylene glycol 1000 succinate(TPGS) PHOSPHATIDYLCHOLINE Antioxidant activity Oral absorption

Formulation of self-nanoemulsifying drug delivery systems containing monoacyl phosphatidylcholine and Kolliphor^(■) RH40 using experimental design被引量：1: 《Asian Journal of Pharmaceutical Sciences》2018年第6期536-545,共10页Thuy Tran Thomas Rades Anette Müllertz; Financial support from the University of Copenhagen and the Phospholipid Research Center(Heidelberg,Germany)is kindly acknowledged; The development of self-nanoemulsifying drug delivery systems(SNEDDS) to enhance the oral bioavailability of lipophilic drugs is usually based on traditional one-factor-at-a-time approaches. These approaches may be in...; 关键词：Monoacyl phosphatidylcholine Self-nanoemulsifying drug delivery systems D-optimal design Polyoxyl 40 hydrogenated castor oil Kolliphor^(■)(RH40) Droplet size Cryogenic transmission electron MICROSCOPY

Moderating effect of synthesized docosahexaenoic acid-enriched phosphatidylcholine on production of Th1 and Th2 cytokine in lipopolysaccharide-induced inflammation被引量：2: 《Asian Pacific Journal of Tropical Biomedicine》2018年第7期340-344,共5页M.Choi JY.Baek I.Park SY.Lim; supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Science,ICT and Future Planning(NRF-2017R1A2B4005915); Objective: To evaluate effects of docosahexaenoic acid-enriched phosphatidylcholine(DHAPC) on cytokine production induced by lipopolysaccharide(LPS). Methods: The culture supernatants of splenocytes exposed to DHA-PC ...; 关键词：Docosahexaenoic acid PHOSPHATIDYLCHOLINE Cytokines INTERLEUKIN-2 INTERLEUKIN-6 Interleukin-12/IL-23(p40)

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