GONOCYTE

作品数:4被引量:11H指数:3
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Dissecting Human Gonadal Cell Lineage Specification and Sex Determination Using A Single-cell RNA-seq Approach被引量:3
《Genomics, Proteomics & Bioinformatics》2022年第2期223-245,共23页Rui Wang Xixi Liu Li Li Ming Yang Jun Yong Fan Zhai Lu Wen Liying Yan Jie Qiao Fuchou Tang 
supported by the National Key R&D Program of China(Grant No.2018YFA0107601).
Gonadal somatic cells are the main players in gonad development and are important for sex determination and germ cell development.Here,using a time-series single-cell RNA sequencing(scRNA-seq)strategy,we analyzed feta...
关键词:Human gonad scRNA-seq Turner syndrome Leydig-Sertoli cell-cell interaction Gonocyte-tospermatogonium transition 
Gene expression dynamics during the gonocyte to spermatogonia transition and spermatogenesis in the domestic yak被引量:4
《Journal of Animal Science and Biotechnology》2019年第4期907-918,共12页Guowen Wang Yongchang Li Qilin Yang Shangrong Xu Shike Ma Rongge Yan Ruina Zhang Gongxue Jia Deqiang Ai Qi’en Yang 
supported by National Key Research&Development Project grant(2016YFC0501805);Qinghai Department of Science and Technology grants(2017-NK-154 and 2016-ZJ-917Q);a STS grant from Chinese Academy of Sciences(KFJ-STS-QYZD-113);supported by the CAS“100 Talents” and Qinghai “1000 Talents” programs;funded by CAS “Light of West China Foundation”
Background:Spermatogenesis is a cellular differentiation process that includes three major events:mitosis of spermatogonia,meiosis of spermatocytes and spermiogenesis.Steady-state spermatogenesis relies on functions o...
关键词:GONOCYTE MEIOSIS SPERMATOGENESIS SPERMATOGONIA TRANSCRIPTOME 
A critical role of PUMA in maintenance of genomic integrity of murine spermatogonial stem cell precursors after genotoxic stress被引量:4
《Cell Research》2009年第8期1018-1030,共13页Anne Forand 
Neonatal gonocytes are precursors of spermatogonial stem cells. Preserving their integrity by elimination of damaged germ cells may be crucial to avoid the transmission of genetic alterations to progeny. Using 7-irrad...
关键词:cell death GONOCYTE PUMA apoptosis CASPASE radiation 
Epidermal growth factor receptor pathway substrate 8 (Eps8) expression in maturing testis
《Asian Journal of Andrology》2004年第3期195-203,共9页Alain Wunsch Kai Strothmann Manuela Simoni Jorg Gromoll Eberhard Nieschlag C.Marc Luetjens 
Aim: Although epidermal growth factor receptors are expressed in the testes, whether they signal through epidermal growth factor receptor pathway substrate 8 (Eps8) is unknown. Here we evaluated the expression pattern...
关键词:gene expression ISOFORM Sertoli cell GONOCYTE 
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