supported by the National Key R&D Program of China(Grant No.2018YFA0107601).
Gonadal somatic cells are the main players in gonad development and are important for sex determination and germ cell development.Here,using a time-series single-cell RNA sequencing(scRNA-seq)strategy,we analyzed feta...
supported by National Key Research&Development Project grant(2016YFC0501805);Qinghai Department of Science and Technology grants(2017-NK-154 and 2016-ZJ-917Q);a STS grant from Chinese Academy of Sciences(KFJ-STS-QYZD-113);supported by the CAS“100 Talents” and Qinghai “1000 Talents” programs;funded by CAS “Light of West China Foundation”
Background:Spermatogenesis is a cellular differentiation process that includes three major events:mitosis of spermatogonia,meiosis of spermatocytes and spermiogenesis.Steady-state spermatogenesis relies on functions o...
Neonatal gonocytes are precursors of spermatogonial stem cells. Preserving their integrity by elimination of damaged germ cells may be crucial to avoid the transmission of genetic alterations to progeny. Using 7-irrad...
Aim: Although epidermal growth factor receptors are expressed in the testes, whether they signal through epidermal growth factor receptor pathway substrate 8 (Eps8) is unknown. Here we evaluated the expression pattern...