SESAMIN

作品数：22被引量：44H指数：3
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相关领域：医药卫生更多>>
相关作者：周仁杰吴静雷红刘末鲁曼霞更多>>
相关机构：合肥工业大学南京财经大学韩国中央大学湖南中医药大学更多>>
相关期刊：《Oil Crop Science》《Acta Pharmacologica Sinica》《中草药》《Journal of Integrative Agriculture》更多>>
相关基金：国家自然科学基金安徽省自然科学基金湖南省自然科学基金博士科研启动基金更多>>
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Sesamin is an effective spleen tyrosine kinase inhibitor against IgE-mediated food allergy in computational,cell-based and animal studies
《Food Science and Human Wellness》2025年第2期469-483,共15页Yu Li Xuerui Chen Longhua Xu Xintong Tan Dapeng Li Dongxiao Sun-Waterhouse Feng Li 
Incubation Program of Youth Innovation in Shandong Province;Key Research and Development Program of Shandong Province(2021TZXD007)。
Food allergy has become a global concern.Spleen tyrosine kinase(SYK)inhibitors are promising therapeutics against allergic disorders.In this study,a total of 300 natural phenolic compounds were firstly subjected to vi...
关键词：Food allergy Spleen tyrosine kinase SESAMIN Computational tools RBL-2H3 cells BALB/c mice 
Potential immunomodulatory role of sesamin in combating immune dysregulation associated with COVID-19
《Asian Pacific Journal of Tropical Biomedicine》2021年第10期421-428,共8页Amin F.Majdalawieh Sarah M.Yousef Imad A.Abu-Yousef 
The ongoing outbreak of novel coronavirus disease 2019(COVID-19),caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),has caused an unprecedented global health crisis.Development of a cure for this de...
关键词：SESAMIN SARS-CoV-2 COVID-19 IMMUNOMODULATION ANTI-INFLAMMATORY Cytokine storm Th1/Th2 balance 
HPLC法同时检测16种五加属植物中14种苯丙素类成分被引量：3
《中草药》2020年第14期3791-3796,共6页肖珊 罗姣 许忠 黄完均 肖瑾 鲁曼霞 卢茂芳 刘向前 
湖南省自然科学基金项目(2019JJ40223);湖南省自然科学基金项目(2019JJ50448);湖南省教育厅一般项目(18C0399);湖南中医药大学生物工程重点学科资助(校行科字[2018] 3号)。
目的建立以HPLC法同时检测16种33批五加属植物中紫丁香苷、绿原酸、咖啡酸、对香豆酸、阿魏酸、ethylsyringin、ethylconiferin、(+)-梣皮树脂醇、(±)-松脂素、(±)-丁香脂素、taiwanin C、savinin、helioxanthin、(-)-sesamin 14种苯...
关键词：五加属 苯丙素类 紫丁香苷 绿原酸 咖啡酸 对香豆酸 阿魏酸 ethylsyringin ethylconiferin (+)-梣皮树脂醇 (±)-松脂素 (±)-丁香脂素 taiwanin C savinin helioxanthin (-)-sesamin 
Sesamin alleviates blood-brain barrier disruption in mice with experimental traumatic brain injury被引量：6
《Acta Pharmacologica Sinica》2017年第11期1445-1455,共11页Ying-liang LIU Zhi-ming XU Guo-yuan YANG Dian-xu YANG Jun DING Hao CHEN Fang YUAN Heng-li TIAN 
This work was supported by grants from National Natural Science Foundation of China （No 81471245, 81671207, and 81501657）, and Shanghai Jiao Tong University Medicine-Engineering Research Fund （YG2016QN20）.
Sesamin, a major lignan of sesame oil, was reported to have neuroprotective effects in several brain injury models. However, its protective action in maintaining blood-brain barrier （BBB） integrity has not been stud...
关键词：SESAMIN traumatic brain injury CCl injury bEnd.3 cells oxidative stress apoptosis BBB tight junction proteins 
Inhibition of two stages of melanin synthesis by sesamol,sesamin and sesamolin被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2017年第10期886-895,共10页Montra Srisayam Natthida Weerapreeyakul Kwanjai Kanokmedhakul 
2011 (#542800) and 2012 (#552900), Khon Kaen University Research Funding supported this project
Objective: To investigate the antimelanogenesis properties of three sesame compoundssesamol, sesamin and sesamolin via two stages of melanin synthesis vis-à-vis sunscreen function and enzyme inhibition in melanoma ce...
关键词：SESAMOL SESAMIN SESAMOLIN TYROSINASE TRP-1/TRP-2 Antimelanogenesis 
芝麻素对高糖损伤SH-SY5Y细胞的保护效果及机制被引量：2
《中成药》2016年第8期1678-1683,共6页张慧 宋宇 栗志勇 张婷 
新乡医学院博士科研启动项目(2010)
目的研究芝麻素(sesamin)对高糖所致人神经母细胞瘤(SH-SY5Y)细胞损伤的保护作用及其机制。方法SH-SY5Y细胞接种于含100 mmol/L葡萄糖的培养基并与10、20、40μmol/L芝麻素共同孵育36 h,MTT法测定细胞存活率,比色法测定细胞培养液乳酸...
关键词：芝麻素(sesamin) 高糖 人神经母细胞瘤(SH-SY5Y)细胞 抗氧化 活性氧 NADPH氧化酶 
Sesamin enhances nitric oxide bioactivity in aortas of spontaneously hypertensive rats被引量：1
《中国药理学与毒理学杂志》2015年第S1期38-38,共1页Jie-renYANG XiangKONG WeiLI 
The project supported by the Natural Science Foundation of Anhui Provincial(1308085QH145)
OBJECTIVE To explore the underlying mechanisms involved in the effect of sesamin on aortic NO bioactivity in spontaneously hypertensive rat(SHR).METHODS Sesamin was orally administered for consecutive 8 weeks in SHR.S...
关键词：SESAMIN spontaneously HYPERTENSIVE RAT ENDOTHELIAL 
Effect of Arbuscular Mycorrhizal Fungi and Their Partner Bacteria on the Growth of Sesame Plants and the Concentration of Sesamin in the Seeds
《American Journal of Plant Sciences》2014年第20期3066-3072,共7页Sachie Horii Takaaki Ishii 
Arbuscular mycorrhizal fungi (AMF) can stimulate the plant growth. Pseudomonas sp. (KCIGC01) NBRC109613 isolated from the spores of Glomus clarum IK97, an AMF, is reported to support the plant growth and development a...
关键词：ARBUSCULAR Mycorrhizal Fungi PARTNER BACTERIA SESAMIN SESAMOLIN 
Ameliorating effects of constituents from Cortex Acanthopanacis Radicis on memory impairment in mice induced by scopolamine被引量：2
《Journal of Traditional Chinese Medicine》2014年第1期57-62,共6页Youngjoo Nam Dongung Lee 
OBJECTIVE:To investigate the effects of active constituents extracted from Cortex Acanthopanacis Radicison improving the impaired memory in mice models.METHODS:The mice models of memory impairment were established usi...
关键词：Cortex Acanthopanacis Radicis Stigmas-terol SESAMIN HYPEROSIDE ACETYLCHOLINESTERASE 
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