CYCLOPHILIN

作品数:40被引量:78H指数:5
导出分析报告
相关领域:医药卫生生物学更多>>
相关作者:廖端芳彭金彪武建国郭琰庹勤慧更多>>
相关机构:南华大学南京军区南京总医院中国科学院大学中国科学院更多>>
相关期刊:《中华风湿病学杂志》《Journal of Integrative Plant Biology》《眼科新进展》《中华实验外科杂志》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划国家科技支撑计划国家高技术研究发展计划更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
Nicotinamide mononucleotide protects septic hearts in mice via preventing cyclophilin F modification and lysosomal dysfunction
《Acta Pharmacologica Sinica》2025年第4期976-988,共13页Rui Ni Xiao-yun Ji Ting Cao Xiu-wen Liu Chao Wang Chao Lu Angel Peng Zhu-xu Zhang Guo-Chang Fan Jin Zhang Zhao-liang Su Tian-qing Peng 
supported by the Canadian Institute of Health Research(Grant No.PJT-180304 to TQP);Projects of International Cooperation from Jiangsu,China(Grant No.BZ2024031 to ZLS).
Myocardial dysfunction is a decisive factor of death in septic patients.Cyclophilin F(PPIF)is a major component of the mitochondrial permeability transition pore(mPTP)and acts as a critical mPTP sensitizer triggering ...
关键词:SEPSIS cyclophilin F LPS myocardial dysfunction nicotinamide mononucleotide Mito-TEMPO 
Emerging therapeutic options for non-alcoholic fatty liver disease:A systematic review
《World Journal of Hepatology》2023年第8期1001-1012,共12页Jasmine Tidwell Natalie Balassiano Anjiya Shaikh Mahmoud Nassar 
BACKGROUND Non-alcoholic fatty liver disease(NAFLD)has become a prevalent cause of chronic liver disease and ranks third among the causes of transplantation.In the United States alone,annual medical costs are approxim...
关键词:Non-alcoholic fatty liver disease Non-alcoholic steatohepatitis Cyclophilin inhibitors Fibroblast growth factor 21 analogs Dual peroxisome proliferator-activated receptor agonists Pan peroxisome proliferator-activated receptor agonists 
血清Cyclophilin A对重型颅脑损伤患者的预后价值分析
《中文科技期刊数据库(全文版)医药卫生》2023年第2期158-160,共3页陈太董 
探究血清Cyclophilin A(Cyp A)对重型颅脑损伤患者的预后价值。方法:回顾性分析2020年1月至2022年11月海南省琼海市人民医院神经外科收治的重型颅脑损伤患者的临床资料,根据28d预后分为存活组(104例)与死亡组(31例),采用二元Logistic回...
关键词:血清Cyclophilin A 重型颅脑损伤 预后价值 
Identification,Isolation and Characterization of GaCyPI Gene in Gossypium arboreum under Cotton Leaf Curl Virus Disease Stress
《Phyton-International Journal of Experimental Botany》2021年第6期1613-1632,共20页Zunaira Sher Muhammad Umair Majid Sameera Hassan Fatima Batool Beenish Aftab Bushra Rashid 
Funds are provided by Higher Education Commission(HEC),Pakistan to Dr.Bushra Rashid;Principal Investigator of the Project No.20-3692/NRPU/R&D/HEC/14 to complete this study。
Pakistan is facing the threat of Cotton Leaf Curl Virus(CLCuV)which is transmitted through whitefly to cotton crop.Molecular mechanism of leaf epicuticular wax protects the plants from different pathogens including in...
关键词:COTTON plant wax virus transmission cyclophilin gene family expressed sequence tag 
Caveolin-1结合Cyclophilin A改善大鼠血管平滑肌细胞胆固醇蓄积
《中南医学科学杂志》2020年第3期257-262,268,共7页郭琰 徐琳 马骏 向定成 阮云军 曾娅玲 黄建玉 廖端芳 
国家自然科学基金(编号:61976222);广东省医学科学技术研究基金项目(编号:A2018318);广东省自然科学基金项目(编号:2016A030313755).
观察caveolin-1和cyclophilin A在血管平滑肌细胞荷脂过程中的表达变化及其对细胞内胆固醇蓄积的影响。实验采用Western-blot、免疫荧光法分别定量,定位检测caveolin-1和cyclophilin A蛋白的表达;油红O染色观察细胞内脂滴的形成情况;高...
关键词:CAVEOLIN-1 CYCLOPHILIN A 血管平滑肌细胞 胆固醇 
北柴胡不同部位柴胡皂苷含量与其关键酶基因表达量的相关性研究被引量:15
《中草药》2019年第10期2433-2441,共9页赵钰 杨林林 韩梅 杨利民 
国家中药材产业技术体系项目(CARS-21)
目的筛选适宜北柴胡Bupleurum chinense表达分析的内参基因,并分析不同部位中柴胡皂苷含量与其关键酶基因表达的关系。方法以北柴胡根、茎、叶、果为实验材料,利用实时荧光定量PCR技术,选取Actin、α-tubublin、β-tubulin、Cyclophilin...
关键词:北柴胡 柴胡皂苷 关键酶基因 ACTIN α-tubublin Β-TUBULIN CYCLOPHILIN EF-1α 
CypA Regulates AIP4-Mediated M1 Ubiquitination of Influenza A Virus被引量:4
《Virologica Sinica》2018年第5期440-448,共9页Madina Mahesutihan Weinan Zheng Liang Cui Yun Li Pengtao Jiao Wenxian Yang Wei Liu Jing Li Wenhui Fan Limin Yang Wenjun Liu Lei Sun 
supported by grants from the National Natural Science Foundation of China (31630079,31672531,31572526,and 31802164);the National Key R&D Program of China (2016YFD0500206,2015BAD11B02);the Strategic Priority Research Program of Chinese Academy of Sciences (XDB29010000);the National Science and Technology Major Project (2018ZX10101004);the Emergency Technology Research Issue on Prevention and Control for Human Infection with A (H7N9) Avian Influenza Virus (10600100000015001206);Wenjun Liu is the principal investigator of the Innovative Research Group of National Natural Science Foundation of China (Grant No.81621091)
Cyclophilin A (CypA) is a peptidyl-prolyl cis/trans isomerase that interacts with the matrix protein (M1) of influenza A virus (IAV) and restricts virus replication by regulating the ubiquitin–proteasome-mediated deg...
关键词:INFLUENZA A virus (IAV) UBIQUITINATION CYCLOPHILIN A (CypA) AIP4 M1 
A zinc finger protein, interacted with cyclophilin,affects root development via IAA pathway in rice被引量:4
《Journal of Integrative Plant Biology》2017年第7期496-505,共10页Peng Cui Hongbo Liu Songlin Ruan Basharat Ali Rafaqat Ali Gill Huasheng Ma Zhifu Zheng Weijun Zhou 
supported by the Special Fund for Agroscientific Research in the Public Interest(201303022);National Natural Science Foundation of China(31301272,31570434);the Fund from Zhejiang A&F University(2013FR022);Zhejiang Provincial Top Key Discipline of Biology and its Open Foundation(2015D19)
The plant hormone auxin plays a crucial role in lateral root development. To better understand the rnolecular mechanisms underlying lateral root formation, an auxin-responsive gene OsCYP2 (Oso2g0121300) was characte...
关键词:IAA of gene ROOT A zinc finger protein ZFP RNAI with 
Correlation of serum cyclophilin A and monocyte chemoattractant protein-1 levels with carotid atherosclerosis in patients with acute cerebral infarction被引量:1
《Journal of Hainan Medical University》2017年第11期150-153,共4页Jun Jia Liang Huang Zhan-Hua Zhang 
Objective:To study the correlation of serum cyclophilin A (CyPA) and monocyte chemoattractant protein-1 (MCP-1) levels with carotid atherosclerosis in patients with acute cerebral infarction.Methods: 106 patients with...
关键词:Acute cerebral INFARCTION CYCLOPHILIN A MONOCYTE CHEMOATTRACTANT protein-1 CAROTID ATHEROSCLEROSIS 
脊椎动物Cyclophilin A肽基脯氨酰顺反异构酶活性及遗传变异分析被引量:3
《遗传》2016年第8期736-745,共10页任丽倩 刘薇 李文博 刘文军 孙蕾 
国家自然科学基金项目(编号:31472178,81271849);国家科技支撑计划项目(编号:2015BAD11B02)资助~~
Cyclophilin A(简称CypA)由PPIA(Peptidylprolyl isomerase A)基因编码,是典型的Cyclophilin家族蛋白,具有肽基脯氨酰顺反异构酶活性,在蛋白质的折叠和转运、信号转导、炎症、免疫调节、细胞凋亡及病毒复制等生物学过程中发挥着重要作...
关键词:脊椎动物 CYCLOPHILIN A 肽基脯氨酰顺反异构酶 分子进化 
检索报告 对象比较 聚类工具 使用帮助 返回顶部