GLIOGENESIS

作品数:8被引量:10H指数:2
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相关领域:医药卫生生物学更多>>
相关作者:邱林朱长连王小阳徐发林更多>>
相关机构:郑州大学第三附属医院更多>>
相关期刊:《Neural Regeneration Research》《Neuroscience Bulletin》《Protein & Cell》更多>>
相关基金:国家自然科学基金上海市浦江人才计划项目上海市教育委员会重点学科基金国家教育部博士点基金更多>>
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The Principle of Cortical Development and Evolution
《Neuroscience Bulletin》2025年第3期461-485,共25页Zhengang Yang 
supported by the Ministry of Science and Technology of China(STI2030-2021ZD0202300);the National Natural Science Foundation of China(32070971,32100768,32200776,and 32200792);the Shanghai Municipal Science and Technology Major Project(2018SHZDZX01)。
Human’s robust cognitive abilities,including creativity and language,are made possible,at least in large part,by evolutionary changes made to the cerebral cortex.This paper reviews the biology and evolution of mammal...
关键词:Radial glia Cortical neurogenesis Cortical gliogenesis Cortical expansion Cortical evolution FGFERK signaling SHH signaling BMP7 INTERNEURON Human-specific gene 
BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period
《Protein & Cell》2024年第1期21-35,共15页Zhenmeiyu Li Guoping Liu Lin Yang Mengge Sun Zhuangzhi Zhang Zhejun Xu Yanjing Gao Xin Jiang Zihao Su Xiaosu Li Zhengang Yang 
supported by the Ministry of Science and Technology of China (STI2030-2021ZD0202300);National Natural Science Foundation of China (NSFC 31820103006,32070971,32100768,32200776,and 32200792);Shanghai Municipal Science and Technology Major Project (No.2018SHZDZX01);ZJ Lab,and Shanghai Center for Brain Science and Brain-Inspired Technology.
The seat of human intelligence is the human cerebral cortex,which is responsible for our exceptional cognitive abilities.Identifying principles that lead to the development of the large-sized human cerebral cortex wil...
关键词:radial glia cortical neurogenesis cortical gliogenesis cortical evolution BMP7 SHH 
Interplay of SOX transcription factors and microRNAs in the brain under physiological and pathological conditions被引量:2
《Neural Regeneration Research》2022年第11期2325-2334,共10页Milena Stevanovic Danijela Stanisavljevic Ninkovic Marija Mojsin Danijela Drakulic Marija Schwirtlich 
the Ministry of Education,Science and Technological Development of the Republic of Serbia(Agreement number 451-03-9/2021-14/200042,to MiS,DSN,MM,DD and MaS);the Serbian Academy of Sciences and Arts(Grant number F24,to MiS(PI),MM,DD and MaS)。
Precise tuning of gene expression,accomplished by regulato ry networks of transcription factors,epigenetic modifiers,and microRNAs,is crucial for the proper neural development and function of the brain cells.The SOX t...
关键词:dysregulation of miRNA expression glioblastoma GLIOGENESIS glioma stem cells ischemic stroke neural stem cells neural tissue regeneration neurodegenerative diseases NEURODEVELOPMENT NEUROGENESIS SOX/miRNA interplay traumatic brain injury 
Physiological and pathological effects of amyloid-β species in neural stem cell biology被引量:1
《Neural Regeneration Research》2019年第12期2035-2042,共8页Adela Bernabeu-Zornoza Raquel Coronel Charlotte Palmer María Monteagudo Alberto Zambrano Isabel Liste 
supported by grants from the MICINN-ISCⅢ(PI-10/00291 and MPY1412/09);MINECO(SAF2015-71140-R);Comunidad de Madrid(NEUROSTEMCM consortium; S2010/BMD-2336)(all to IL)
Although amyloid-β peptide is considered neurotoxic, it may mediate several physiological processes during embryonic development and in the adult brain. The pathological function of amyloid-β peptide has been extens...
关键词:amyloid-β peptide  NEURAL stem CELLS NEURAL PROGENITOR CELLS Alzheimer's disease AMYLOID precursor protein toxicity neurogenesis GLIOGENESIS GSK3β 
Unmasking the responses of the stem cells and progenitors in the subventricular zone after neonatal and pediatric brain injuries
《Neural Regeneration Research》2016年第1期45-48,共4页Mariano Guardia Clausi Ekta Kumari Steven W.Levison 
There is great interest in the regenerative potential of the neural stem cells and progenitors that populate the subventricular zone(SVZ). However, a comprehensive understanding of SVZ cell responses to brain injuri...
关键词:CNS regeneration cytokines glial progenitors gliogenesis inflammation cerebral palsy traumatic brain injury stroke 
A Disintegrin and Metalloprotease 10 in neuronal maturation and gliogenesis during cortex development被引量:1
《Neural Regeneration Research》2013年第1期24-30,共7页Zhixing Ma Qingyu Li Zhengyu Zhang Yufang Zheng 
supported by the National Natural Science Foundation of China,No.30800322;Shanghai Pujiang Program,No.08PJ1401300;Shanghai Leading Academic Discipline Project,No.B111;Ministry of Education Research Fund for New Teachers in Doctoral Program of Higher Educational Institutes,No.200802461050;National Basic Research Program of China(973 Program),No.2011CB503703;Ministry of Education Start Fund to Returned Overseas Scholars;Zhuo Xue Program of Fudan University
The multiple-layer structure of the cerebral cortex is important for its functions. Such a structure is generated based on the proliferation and differentiation of neural stem/progenitor cells. Notch functions as a mo...
关键词:neural regeneration neurogenesis ADAM10 A Disintegrin and Metalloprotease NOTCH Notchintracellular domain TujlS100 Nestin cerebral cortex DEVELOPMENT neuronal maturation glialcell grants-supported paper photographs-containing paper neuroregeneration 
Epigenetic control on cell fate choice in neural stem cells被引量:5
《Protein & Cell》2012年第4期278-290,共13页Xiao-Ling Hu Yuping Wang Qin Shen 
supported by grants from the National Natural Science Foundation of China(Grant No.2012CB966701);the Ministry of Science and Technology of the People’s Republic of China.
Derived from neural stem cells(NSCs)and progenitor cells originated from the neuroectoderm,the nervous system presents an unprecedented degree of cellular diversity,interwoven to ensure correct connections for propaga...
关键词:neural stem cells(NSCs) epigenetic regu-lation NEUROGENESIS GLIOGENESIS radial glial cell cerebral cortex subventricular zone(SVZ) DNA methylation histone modification 
Changes of cell proliferation and differentiation in the developing brain of mouse被引量:1
《Neuroscience Bulletin》2007年第1期46-52,共7页邱林 朱长连 王小阳 徐发林 
This work was supported by the grant of National Natural Science Foundation of China (No. 30470598).
Objective To investigate the cell proliferation and differentiation in the developing brain of mouse. Methods C57/BL6 mice were divided into 3 groups at random. Bromodeoxyuridine (BrdU) was injected into the brains ...
关键词:brain development NEUROGENESIS GLIOGENESIS 
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