Background: Elastomeric pumps (elastic balls into which analgesics or antibiotics can be inserted) push medicines through a catheter to a nerve or blood vessel. Since elastomeric pumps are small and need no power sour...
National Natural Science Youth Fund,Grant/Award Number:82202326;Natural Science Foundation of Shanghai Municipality,Grant/Award Number:21ZR1405300;National Natural Science Foundation of China Youth Fund,Grant/Award Number:52322213;Shanghai Rising-Star Program,Grant/Award Number:21QA1400900;National Funds for General Projects,Grant/Award Number:52272269;Innovation Program of Shanghai Municipal Education Commission,Grant/Award Number:2023ZKZD01;Key Program of National Natural Science Foundation of China,Grant/Award Number:22235004。
Chronic pain is a major cause of suffering that often accompanies diseases and therapies,affecting approximately 20%of individuals at some point in their lives.However,current treatment modalities,such as anesthetic a...
grants from the National Natural Science Foundation of China(31720103908 and31530028);the National Key Technology Support Program of the Ministry of Science and Technology of China(2017YFA0701300)
Investigation of pain requires measurements of nociceptive sensitivity and other pain-related behaviors.Recent studies have indicated the superiority of gait analysis over traditional evaluations(e.g., skin sensitivit...
The Nav1.7 channel represents a promising target for pain relief. In the recent decades, a number of Nav1.7 channel inhibitors have been developed. According to the effects on channel kinetics, these inhibitors could ...
OBJECTIVE: The main objectives of this study were to qualitatively evaluate the profile of phytochemical constituents present in methanolic extract of Microcos paniculata bark(BME) and fruit(FME), as well as to e...
This work was supported financially and inspired scientifically by Prof.Yongxian Cheng of State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences,and Prof.Baomin Fan of Key Laboratory of Chemistry in Ethnic Medicinal Resources,State Ethnic Affairs Commission&Ministry of Education,Yunnan University of Nationalities.
We report the first total synthesis of four possible absolute configurations and four other regional isomers of a naturally occurring alkaloid crotonine,which was isolated from Croton tiglium L.(Euphoriaceae)without e...
Supported by the Administration of Traditional Chinese Medicine of Guangdong Province,China (No. 2010431)
OBJECTIVE:To observe the curative effect of an acupoint application with a Dingqi analgesic patch on moderate to severe pain caused by liver cancer.METHODS:Forty patients with moderate to severe pain caused by liver c...
The analgesic effect of Semen Coicis was observed with the sequential trial in 26 cases of severe functional dysmenorrhea. The results showed that the markedly effective rate was 90%, which was much better than th...