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作品数:370被引量:683H指数:12
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相关领域:医药卫生更多>>
相关作者:闫虹程慧芳王学梅李响张义侠更多>>
相关机构:郑州大学中国医科大学附属第一医院石河子大学北京大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国博士后科学基金更多>>
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Utilizing a microfluidic device to enrich and fluorescently detect circulating tumor cells
《Science Bulletin》2017年第7期453-455,共3页Ya-Nan Chang Mingyi Zhang Juan Li Kui Chen Weihong Gu Gengmei Xing 
supported by the National Basic Research Program of China(2015CB932100,2013CB932703);the National Natural Science Foundation of China(11405185)
Circulating tumor cells(CTCs)are cancer cells that have propagated from primary tumor sites,spreading into the bloodstream as the cellular origin of fatal metastasis,and to secondary tumor sites.Capturing and analyzin...
关键词:QDS CELL LINE MCF Utilizing a microfluidic device to enrich and fluorescently detect circulating tumor cells 
A machine learning-based method to detect fluorescent spots and an accelerated, parallel implementation of this method
《Chinese Science Bulletin》2014年第28期3573-3578,共6页Bei Liu Wanjuan Feng Tao Xu Wei Ji 
supported by the National Natural Science Foundation of China(31130065,31100615)
Under most microscopes, the fluorescent signals emitted from biological structures, such as vesicles, as well as the signals from single molecules will appear as small puncta, which contribute to a Gaussian-like distr...
关键词:机器学习算法 荧光 检测 并行实现 基础 斑点 生物结构 NALS 
Ability to detect weak effective seismic signals by utilizing chaotic vibrator system被引量:6
《Chinese Science Bulletin》2006年第24期3010-3017,共8页LI Yue YANG Baojun YUAN Ye ZHAO Xueping LIN Hongbo 
Acknowledgements The work was financially supported by the National Natural Science Foundation of China (Grant Nos. 40374045, 40574051) and the Science and Technology Development Project of Jilin Province (Grant No. 20050526).
Taking the advantage of CVS (Chaotic Vibrator System) sensitivity of large-scale periodic phase-state response to quasi-periodic or periodic signals,a series of numerical experiments were made to understand the abilit...
关键词:地震勘探 地震信号 弱有效信号 信噪比 杂乱震荡器系统 
Using maximum likelihood method to detect adaptive evolution of HCV envelope protein-coding genes
《Chinese Science Bulletin》2006年第18期2236-2242,共7页ZHANG Wenjuan ZHANG Yuan ZHONG Yang 
Nonsynonymous-synonymous substitu- tion rate ratio (dN/dS) is an important measure for evaluating selective pressure based on the pro- tein-coding sequences. Maximum likelihood (ML) method with codon-substitution mode...
关键词:适应进化 阳性选择 氨基酸 肝炎病毒 包膜蛋白 HCV 
F-MSAP:A practical system to detect methylation in chicken genome被引量:11
《Chinese Science Bulletin》2005年第18期2039-2044,共6页XU Qing SUN Dongxiao ZHANG Yuan 
supported by National Natural Scientific Foundation of China(Grant No.30200193);the State Ma-jor Basic Research Development Program(Grant No.GT2000016105).
By replacing radiation with fluorescent system in the technique of methylation sensitive amplified polymor-phism (MSAP) and optimizing reaction conditions, a modi-fied technique to detect DNA methylation called F-MSAP...
关键词:小鸡 基因组 多态现象 DNA 甲基化物 荧光性 
Experimental exploration to thermal infrared imaging for detecting the transient process of solid impact被引量:3
《Chinese Science Bulletin》2001年第10期872-877,共6页Lixin Wu Huanping Wu Guohua Li 
The work was supported by the Doctoral Funds of the Ministry of Education of China (Grant No. 98029007); and the Natural Science Funds of Beijing (Grant No. 8001003).
Based on the analysis and the comparison of stress pattern analysis by thermal emission (SPATE) and remote sensing rock mechanics (RSRM), the idea to detect the transient process of solid impact with thermal infrared ...
关键词:TIR imaging SOLID IMPACT TRANSIENT DETECT REMOTE sensing RSRM. 
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