BIOTIN

作品数:67被引量:71H指数:5
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Streptavidin-Biotin Complexes as Tools for Modulating an Important DNA Episgenetic Modification
《Chinese Journal of Chemistry》2024年第18期2166-2172,共7页Yongjie Liu Xinyan Xu Xingyu Liu Wei Xiong Qianqian Qi Yuanyuan Zhang Jinxuan Hou Tian Tian Xiang Zhoua 
the National Natural Science Foundation of China(Nos.22177089,21721005,92153303,22037004,22177088);the Fundamental Research Funds for the Central Universities(2042021kf0211);Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University(Grant No.ZNJC202309).
DNA 5-formylcytosine(5fC)is a prominent epigenetic modification within biological systems.Recent investigations have shed light on its pivotal role in governing cell fate,gene expression,and disease pathways.However,o...
关键词:Epigenetic modification BIOTIN STREPTAVIDIN SELECTIVITY REGULATION 
Semi-synthesis of biotin-bearing activity-based ubiquitin probes through sequential enzymatic ligation,N-S acyl transfer and aminolysis reaction
《Chinese Chemical Letters》2023年第6期362-365,共4页Yu Wang Qiong Xia Xiao Hua Yanyan Guo Jing Shi Yi-Ming Li 
supported by the National Key R&D Program of China(No.2017YFA0505400);the National Natural Science Foundation of China(Nos.21877024,21972214 and 22277020)。
Activity-based Ubiquitin probes(Ub-ABPs)carrying a reporter group have emerged as effective tools for the investigation of deubiquitinating enzymes(DUBs),such as studying the molecular mechanism of DUBs,profiling new ...
关键词:UBIQUITINATION Deubiquitinating enzyme Activity-based ubiquitin probes Biotin tag Protein semi-synthesis 
Intracellular Self-assembly of TPE-biotin Nanoparticles Enables Aggregation-Induced Emission Fluorescence for Cancer-Targeted Imaging
《Chinese Journal of Chemical Physics》2018年第6期851-856,734,共7页Yi-fei Xu Jin-hui Jiang 
supported by Anhui Scientific and Technological Project(No.1704a0802164);the Natural Science Foundation of the Anhui Higher Education Institutions of China(No.KJ2018A0192)
Fluorogens with aggregation-induced emission (AIE) characteristics have recently been widely applied for studying biological events, and fluorogens with “smart” properties are especially desirable. Herein, we ration...
关键词:TETRAPHENYLETHYLENE BIOTIN SELF-ASSEMBLY Aggregation-induced emission 
Development of BCPDA-Eu^3+-BAS Labeled Hepatitis B Surface Antibodies被引量:4
《Chemical Research in Chinese Universities》2018年第1期24-27,共4页TAN Wenjia SUN Zhixia XUAN Lili LI Junling XIE Wenbing HE Chengyan PAN Lihua 
Supported by the National Natural Science Foundation of China(No. 81572082) and the Natural Science Foundation of Jilin Province, China(Nos.2011713, 20150414015GH, 20150204010YY).
The effect of the chelating agent 4,7-bis(chlorosulfophenyl)-1,10-phenanthroline-2,9-dicarboxylic acid (BCPDA) labeled hepatitis B surface antibodies(HBsAb) on time-resolved fluoroimmunoassays(TRFIA) was inves...
关键词:Time-resolved fluorescence immunoassay BIOTIN STREPTAVIDIN 
A Convenient "Turn On-off" Phosphorescent Nanosensor for Detection of Biotin Based on Quantum Dots/CTAB
《Chemical Research in Chinese Universities》2016年第6期917-923,共7页FANG Xiaoxing ZHENG Ji YAN Guiqin 
A switchable room-temperature phosphorescence(RTP) nanosensor based on an MPA-capped Mn-dopedZnS QDs/CTAB composite system(MPA=3-mercaptopropionic acid; CTAB=cetyltrimethyl ammonium bromide;QDs=quantum dots) was e...
关键词:BIOTIN NANOSENSOR Quantum dot Room-temperature PHOSPHORESCENCE 
Binding of Streptavidin to Surface-attached Biotin with Different Spacer Thicknesses
《Journal of Wuhan University of Technology(Materials Science)》2015年第6期1304-1309,共6页李易非 张海宁 
The specific binding of receptor to ligand covalently attached to surface with different surface densities was studied using streptavidin-biotin model pair. Biotinylated substrates with different spacer thicknesses as...
关键词:specifi c interaction biotin streptavidin polymer monolayer spacer thickness 
Synthesis of Biotinylated Galiellalactone Analogues
《International Journal of Organic Chemistry》2014年第4期225-235,共11页Zilma Escobar Martin Johansson Anders Bjartell Rebecka Hellsten Olov Sterner 
Two biotinylated derivatives of the fungal metabolite galiellalactone (1) were synthesized in order to facilitate the investigation of the molecular mechanism of action of the galiellalactonoids. Galiellalactone is a ...
关键词:STAT3 Galiellalactone BIOTIN SYNTHESIS 
Label-free Detection of Biotin Using Nanoporous TiO2/DNA Thin-film Coated Wavelength Interrogated Surface Plasmon Resonance Sensors被引量:4
《Chemical Research in Chinese Universities》2014年第1期157-162,共6页LI Qiushun HE Hao WANG Junnan ZHENG Hui SHI Jianguo LI Mingyu DONG Wenfei QI Zhimei 
Supported by the National Natural Science Foundation of China(Nos.91123029, 61077066, 61340032), the National High Technology Research and Development Program of China(No.2012AA063302) and the Natural Science Foundation of Shandong Province, China(No.ZR2012CM029).
The sensing sensitivity of the wavelength interrogated surface plasmon resonance(WISPR) biosensor could be improved by self-assembly of nanoporous thin-film of TiO2 nanoparticles/DNA(TiO2/DNA)n(n is the number of...
关键词:Nanoporous film Sensing sensitivity BIOTIN Wavelength interrogated surface plasmon resonance 
Different Biotinylation Strategies for Competitive Immunoassay of Estradiol
《Chinese Journal of Chemistry》2004年第7期708-713,共6页赵金富 王永成 李元宗 常文保 
Project supported by the National Natural Science Foundation of China (No. 20175002).
Study on biotinylation strategies for competitive immunoassay of estradiol (E2) was carried out. Two types of competitive enzyme immunoassay (EIA) with Biotin-Avidin amplification system were established and optimized...
关键词:ESTRADIOL SERUM EIA BIOTIN AVIDIN 
Amplified DNA Detection Sensitivity Using Streptavidin-Biotinylated Protein Complex: Characterization by Electrochemical Impedance Spectroscopy
《Chinese Journal of Chemistry》2003年第10期1344-1348,共5页程志亮 杨帆 黄海珍 杨秀荣 
ProjectsupportedbytheNationalNaturalScienceFoundationofChina (No .2 0 0 75 0 2 7)
Thiol terminated oligonucleotide was immobilized to gold surface by self assembly method. A novel amplification strategy was introduced for improving the sensitivity of DNA hybridization using biotin labeled protein...
关键词:DNA hybridization AMPLIFICATION biotin streptavidin electrochemical impedance spectroscopy 
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