supported by the AMS Funding Project(No.ZZB2023C7010).
Glial fibrillary acidic protein(GFAP)is one of the discriminative biomarkers for diagnosing traumatic brain injury(TBI),and accurate determination of GFAP is clinically significant.In this study,a novel fluorescence i...
supported financially by the National Natural Science Foundation of China(NSFC,Nos.62071119 and 62075098);the National Key Research and Development Program of China(Nos.2017YFA0205301 and 2018YFC1602905)。
The extracellular vesicles show great potential as a noninvasive biomarker for the early detection of cancer.Hence,there is an urgent requirement to create biosensors that are time-saving,simple,and easily scalable in...
the National Natural Science Foundation of China(Nos.22177089,21721005,92153303,22037004,22177088);the Fundamental Research Funds for the Central Universities(2042021kf0211);Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University(Grant No.ZNJC202309).
DNA 5-formylcytosine(5fC)is a prominent epigenetic modification within biological systems.Recent investigations have shed light on its pivotal role in governing cell fate,gene expression,and disease pathways.However,o...
the National Natural Science Foundation of China(Nos.22177089,21721005,92153303,22037004,22177088);the Fundamental Research Funds for the Central Universities(2042023kf0204);Translational Medicine and Interdisciplinary Research Joint Fund of Zhongnan Hospital of Wuhan University(Grant No.ZNJC202309).
Comprehensive Summary Currently,CRISPR/Cas9 technology has found widespread applications across various domains.However,the utility of CRISPR/Cas9 is encumbered by issues pertaining to its reliability and safety,prima...
New reagents for immunofluorescence analysis of carbazole series containing fluorinated β-dicarbonyl fragments and carboxylic substituent groups separated by spacers of different lengths from the light-gathering carb...
the National Natural Science Foundation of China(Nos.22076221,21876208);the Program for Innovative Research Team of Science and Technology in the University of Henan Province(No.21IRTSTHN005);the Hunan Provincial Science and Technology Plan Project,China(No.2019TP1001)。
We propose a concept for ligase detection by conversion of aggregation-based homogeneous analysis into surface-tethered electrochemical assay through streptavidin(SA)-biotin interaction.Sortase A(Srt A)served as the m...
Supported by Cultivation Fund of National Natural Science Foundation of China Project(202114);Major Program at School Level(201711).
[Objectives]To explore the expression of interleukin 34(IL-34)in gastric adenocarcinoma tissues and its relationship with apoptosis of gastric adenocarcinoma cells.[Methods]60 cases of surgically resected human gastri...
the National Natural Science Foundation of China(21405012 and 81761148028);the Science and Technology Commission of Shanghai Municipality(19XD1400100 and 20DZ2254900);the Shanghai Education Commission through the Shanghai Leading Talents Program,and the 111 Project(BP0719035).
Detection of circulating tumor cells(CTCs)plays an important role in early diagnosis of cancer and personalized therapy.However,isolated CTCs,especially those captured by positive sorting methods,are difficult to cult...
Supported by the National Natural Science Foundation of China(No.21505101);the Natural Science Foundation of Zhejiang Province,China(No.LQ16B050003).
Natural and syntlietic nanopores are increasingly popular tools in biosensors. In this work, the DNA supersandwich structure, which was made from two specially designed probes has been used to be fabricated in solid n...
the Deanship of Scientific Research at King Khalid university for funding this work through research group(R.G.P.1/26/40).
The aim of the current research was to clone and to characterize the partial 66 kDa streptavidin-binding peptide(SBP)found in the germinated embryos of Pisum sativum L.var.Alaska.The pea(P.sativum var.Alaska)embryos p...