support of Professor Xuan Zhang’s research group,Laboratory of pharmaceutics,School of Pharmaceutical Sciences,Peking University;Beijing Kaiao Technology Development Co.,Ltd.
In the present study, we developed a novel open-tubular capillary dectrochromatographic method using avidin-phospholipid vesicle complex as the stationary phase for chiral separation of mexiletine hydrochloride. The a...
This research was supported by National Natural Science Foundation of China (NSFC; 81325010, 81421004 and 31371443) and Special Funding Support of Beijing Municipal Administration of Hospitals, Clinical Medicine Development (ZYLX201701).
The clustered, regularly interspaced, short palin- dromic repeats (CRISPR)/CRISPR-associated protein 9 (Casg) system is a versatile tool for genomic engineering in mammalian cells and organisms, enabling the intro...
In this work an impedimetric immunosensor based on affinity immobilization method of a biotin labelled anti-human IgG antibody, used as a model system, was reported. The experimental procedure involves the growth of a...
Supported by the National Natural Science Foundation of China(Nos.91027010, 21073073, 20903043, 20973075), the Research Fund for the Doctoral Program of Higher Education of China(No.20090061120089) and the National Instrumentation Program(NIP) of the Ministry of Science and Technology of China(No.2011YQ03012408).
A surface-enhanced Raman scattering(SERS) optical fiber sensor was prepared by the laser-induced deposition ofAg nanoparticle membrane on a silica optical fiber tip, which was applied to the real time SERS spectral ...
Avidin-liposome complex is a specific chiral selector used to separate the enantiomers of D,L-tryptophan,D,L-phenylthiohydantoin -serine(D,L-PTH-Ser),D,L-phenylthiohydantoin-threonine(D,L-PTH-Thr) and R,S-pioglita...
Supported by the China Postdoctoral Science Foundation, No. 2003033345Medical Sciences and Technology Foundation of Guangdong Province, No.A2000389
AIM: To evaluate the influence of avidin chase on the side effects of radioimmunotherapy (RIT) in nude mice bearing human colon carcinoma and therapeutic outcome.METHODS: Purified anti-CEA monoclonal antibody (McAb)wa...
Project supported by the National Natural Science Foundation of China (No. 20175002).
Study on biotinylation strategies for competitive immunoassay of estradiol (E2) was carried out. Two types of competitive enzyme immunoassay (EIA) with Biotin-Avidin amplification system were established and optimized...
This work was supported by the National Natural Science Foundation of China(Grant Nos.20102007,29725203 and 20072042);the State Key Program of Basic Research of China(Grant No.2002CB512802);the 863 Hi-Tech Program of China(Grant Nos.2002AA233011,2002AA233061,2001AA235051 and 2001AA 235041);Foundation of Shanghai Ministry of Science and Technology,and the Key Program of New Drug Research and Development from the Chinese Academy of Sciences.
Studies of protein-ligand interactions are helpful to elucidating the mechanisms of ligands, providing clues for rational drug design. The currently developed steered molecular dy- namics (SMD) is a complementary appr...
Surface plasmon resonance (SPR) was a sensitive method to study molecular interactions. Based on the specific binding, this paper presented the molecular assembly of protein nucleic acid multilayers on the surface of...