supported from the Program of National Natural Science Foundation of China(82272279,82072169).
During skin aging,the degeneration of epidermal stem cells(EpiSCs)leads to diminished wound healing capabilities and epidermal disintegration.This study tackles this issue through a comprehensive analysis combining tr...
supported by the National Natural Science Foundation of China(No.31772643);the Special Research Funding for Discipline Construction in Sichuan Agricultural University(No.03570126)
In the present study,the chronic heat stress(CHS)broiler model was developed to investigate the potential protection mechanism of organic selenium(selenomethionine,SeMet)on CHS-induced skeletal muscle growth retardati...
Osteoporosis is a typical physiological disease,the main symptoms of which are brittle fracture,bone pain and easily deformed.As an individual ages,the prevalence of osteoporosis increases year by year.In the present ...
Selenium is a trace element in animal nutrition provided through forage. Vegetation should accumulate adequate levels to meet this livestock requirement. This study assessed southeastern Missouri soils for their selen...
Background: Irritable bowel syndrome (IBS) is a common disorder impairing patient’s quality of life. Currently, there is no effective treatment for this syndrome. Coltect is a dietary supplement containing curcumin, ...
funded by CalFed Project number SP2006-035;University of Wisconsin, Milwaukee (#150-25-3150PRJ93WQ)
An 8-week feeding trial was conducted to investigate the responses of juvenile white sturgeon(Acipenser transmontanus) to elevated dietary selenium(Se) based on the determination of the RNA/DNA ratio in muscle, heat s...
Supported by The Health Research Council of New Zealand
AIM: To prospectively determine the safety and tolerability of oral L-selenomethionine(SLM) with concurrent chemoradiation(CCRT) for Stage Ⅲ non-small cell lung cancer(NSCLC) and estimate if the incidence and/or seve...
Supported by A grant from the Health Research Council of New Zealand(in part)
AIM: To investigate whether selenomethionine(SLM) reduces mucositis incidence in patients with head and neck squamous cell cancer(HNSCC) undergoing concurrent chemoradiation(CRT).METHODS: In this multi-institutional, ...
supported by NOVUS Intl.(MO.USA);The authors are grateful to the company for supplying fund and DL-SeMet samples
Background: This study was designed to evaluate the efficacy of DL-selenomethionine (DL^SeMet) supplementation on growth performance, antioxidant status, plasma selenium (Se) concentration, and immune function of...
Acknowledgements We thank Prof. Jianping Ding at Institute of Biochemistry and Cell Biology (SIBCB), Shanghai Institutes for Biological Sciences (SIBS), Chinese Academy of Sciences (CAS) for the guidance of the project. We are grateful to the staff members at the Shanghai Synchrotron Radiation Facility and the Research Center for Structural Biology of SIBCB, SIBS, CAS for technical supports in diffraction data collection and helpful discussion.This work was supported by the National Natural Science Foundation of China (30972965 and 30800171) and the State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences.
Human transducin-like enhancer of split 1 (TLE1) plays crucial roles in a number of developmental processes and is involved in pathogenesis of malignancy tumors. The N-terminal glutamine-rich domain (Q domain) of ...