TRIAZOLES

作品数：34被引量：49H指数：3
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相关领域：理学化学工程更多>>
相关作者：鲁宽科刘方明陈耀祖更多>>
相关机构：陕西师范大学西北师范大学北京医科大学兰州大学更多>>
相关期刊：《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Science China Chemistry》《International Journal of Organic Chemistry》更多>>
相关基金：国家自然科学基金国家教育部博士点基金重庆市自然科学基金国家重点基础研究发展计划更多>>
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Photocatalytic generation of 1,4-disubstituted 1,2,3-triazoles under metal, oxidant and azide-free conditions
《Green Synthesis and Catalysis》2024年第1期62-67,共6页Changhong Liu Dilshat Abdukerem Wenli Zhu Kun Xia Zechuan Mao Ablimit Abdukader 
The authors acknowledge the financial support from the National Natural Science Foundation of China(Nos.22061040 and 21562039);the Xinjiang Provincial Natural Science Foundation of China(Nos.2022E01069 and 2020D01C024).
Available online A mild and efficient photocatalytic-induced radical method has been developed for[4+1]cycloaddition reaction of 1,4-disubstituted 1,2,3-triazoles with N-tosylhydrazides and primary amines.The reaction...
关键词：PHOTOCATALYTIC TRIAZOLES Cycloaddition reaction Allyl-type radicals 
Controlling antifungal activity with light:Optical regulation of fungal ergosterol biosynthetic pathway with photo-responsive CYP51 inhibitors
《Acta Pharmaceutica Sinica B》2023年第7期3080-3092,共13页Zhuang Li Na Liu Wanzhen Yang Jie Tu Yahui Huang Wei Wang Chunquan Sheng 
supported by the National Natural Science Foundation(81725020,82003591 and 81973175,China);the Innovation Program of Shanghai Municipal Education Commission(2019-01-07-00-07-E00073,China);Science and Technology Commission of Shanghai Municipality(20S11900400,China)。
Invasive fungal infections(IFIs)have been associated with high mortality,highlighting the urgent need for developing novel antifungal strategies.Herein the first light-responsive antifungal agents were designed by opt...
关键词：Antifungal agents Ergosterol biosynthesis TRIAZOLES Photocaged Optical control 
Triazole backbone ligand in an unprecedented efficient manganese catalyst for use in transfer hydrogenation
《Science China Chemistry》2023年第7期2028-2036,共9页Qianqian Liang Chunyan Zhang Fangchao Wang Zhong Luo Wei Yang Guohui Zhang Ding Ding Guoying Zhang 
supported by the National Natural Science Foundation of China(22002067,22202228);the Hundred-Talent Program of the Chinese Academy of Sciences;the Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Shanxi Province(20220052);the Science and Technology Project of Shanxi Province(202103021223457);the State Key Laboratory of Coal Conversion,Institute of Coal Chemistry,Chinese Academy of Sciences(2021BWZ011)
Noble metal catalysts are generally expensive,and thus,abundant 3d metals recently received significant attention as catalysts in catalytic hydrogenation.Mn catalysts are widely applied in transfer hydrogenations,but ...
关键词：manganese catalyst triazoles ligand transfer hydrogenation KETONES alcohols 
[4+1]Annulation of in situ generated azoalkenes with amines:A powerful approach to access 1-substituted 1,2,3-triazoles被引量：1
《Chinese Chemical Letters》2022年第3期1550-1554,共5页Hongwei Wang Yongquan Ning Paramasivam Sivaguru Giuseppe Zanoni Xihe Bi 
supported by the National Natural Science Foundation of China(NSFC,Nos.21871043,21961130376);Department of Science and Technology of Jilin Province(Nos.20180101185JC,20190701012GH,20200801065GH);the Fundamental Research Funds for the Central Universities(Nos.2412019ZD001,2412020ZD003)。
1-Substituted 1,2,3-triazoles represents‘privileged’structural scaffolds of many clinical pharmaceuticals.However,the traditional methods for their preparation mainly rely on thermal[3+2]cycloaddition of potentially...
关键词：[4+1]Annulation Azoalkene Late-stage functionalization 1-Substituted 1 2 3-triazoles 
Rhodium(Ⅱ)-Catalyzed [4+3] Cyclization of Triazoles with Indole Derivatives and Its Application in the Total Synthesis of (±)-Aurantioclavine被引量：1
《Chinese Journal of Chemistry》2021年第5期1145-1152,共8页Shengguo Duan Bing Xue Hui Meng Zihang Ye Ze-Feng Xu Chuan-Ying Li 
the National Natural Science Foundation of China(Nos.21871235,21901230,21801224);the Natural Science Foundation of Zhejiang Province(No.LQ18B020009);the Fundamental Research Funds of Zhejiang Sci-Tech University(2019Y003);the Science Foundation of Zhejiang Sci-Tech University(ZSTU)under Grant No.18062301-Y is gratefully acknowledged.
An efficient rhodium(Ⅱ)-catalyzed[4+3]cyclization reaction of 1-sulfonyl-1,2-3-triazoles and indoles was developed.Azepino[5,4,3-ccflindoles,which are widely distributed in ergot alkaloids with various biological act...
关键词：TRIAZOLES RHODIUM ALKALOIDS CYCLIZATION Aurantioclavine 
Rh-Catalyzed Formal[3+2]Cyclization for the Synthesis of 5-Aryl-2-(quinolin-2-yl)oxazoles and Its Applications in Metal lons Probes被引量：1
《Chinese Journal of Chemistry》2021年第3期621-626,共6页Tongtong Zhou Xinwei He Youpeng Zuo Yuhao Wu Wangcheng Hu Shiwen Zhang Jiahui Duan Yongjia Shang 
the National Natural Sci-ence Foundation of China(No.21772001);the Anhui Provincial Natural Science Foundation(No.1808085MB41);the Cultiva-tion Project for University Outstanding Talents of Anhui Province(2019).
Main observation and conclusion A facile and efficient strategy for the synthesis of 5-aryl-2-(quinolin-2-yl)oxazoles via rhodium-catalyzed formal[3+2]cyclization of 4-aryl-1-tosyl-1H-1,2,3-triazoles with quinoline-2-...
关键词：2-(Quinolin-2-yl)oxazoles CYCLIZATION Metal ions probes CARBENE TRIAZOLES 
Cis-2-dodecenoic Acid Mediates Its Synergistic Effect with Triazoles by Interfering with Efflux Pumps in Fluconazole-resistant Candida albicans被引量：3
《Biomedical and Environmental Sciences》2019年第3期199-209,共11页YANG Dong Liang HU Yan Ling YIN Zi Xin ZENG Gui Sheng LI Dan ZHANG Yu Qian XU Zhen Hua GUAN Xiao Ming WENG Li Xing WANG Lian Hui 
financially supported by the National Natural Science Foundation of China [81273409];the Program for Changjiang Scholars and Innovative Research Team in University [IRT_15R37];the Ministry of Science and Technology of China [2017YFA0205301]
Objective To evaluate the synergy of the Burkholderia signaling molecule cis-2-dodecenoic acid(BDSF) and fluconazole(FLU) or itraconazole(ITRA) against two azole-resistant C. albicans clinical isolates in vitro and in...
关键词：C. ALBICANS Cis-2-dodecenoic acid azole-resistant Combination MDR1 CDR1 
Some New Heterocycles from the Reaction of 4-Carboxaldehyde-2-Phenyl-2H-1,2,3-Triazole Malononitrile
《Natural Science》2017年第12期406-411,共6页Mohamed A. El Sekily Sohayla H. Mancy A. M. El-Ghanam G. A. Leon 
Reaction of 4-carboxaldehyde-2-phenyl-2H-1,2,3-triazole 1 with malononitrile in presence of piperidine afforded the triazolomalonitrile 2 which on treatment with hydrazine hydrate, gave 3-amino-5-(2-phenyl-2H-1,2,3-tr...
关键词：TRIAZOLES Triazole MALONONITRILE PYRAZOLE ISOXAZOLE 
Self-healing hyperbranched polytriazoles prepared by metal-free click polymerization of propiolate and azide monomers被引量：1
《Science China Chemistry》2016年第12期1554-1560,共7页Xin Wang Rongrong Hu Zujin Zhao Anjun Qin Ben Zhong Tang 
supported by the National Natural Science Foundation of China(21525417,21490571,21222402);the key project of the Ministry of Science and Technology of China(2013CB834702);the National Program for Support of Top-Notch Young Professionals,the Fundamental Research Funds for the Central Universities(2015ZY013);the Innovation and Technology Commission of Hong Kong(ITC-CNERC14SC01);support from Guangdong Innovative Research Team Program(201101C0105067115)
The last decade has witnessed the quick develop of self-healing materials. As a newborn strategy, the alternative of irreversible covalent bond formation is, however, to be further developed. In this paper, self-heali...
关键词：SELF-HEALING hyperbranched polytriazole metal-free click polymerization film 
Azo-bridged triazoles: Green energetic materials被引量：5
《Defence Technology（防务技术）》2016年第1期1-15,共15页Lemi TüRKER 
In this short review, excerpts from the literature of azo-bridged triazoles(mainly 1,2,4-triazoles), some of their derivatives(chloromethyl,dinitro and trinitro pyrazole substituted ones, etc.) and some of their salts...
关键词：Azo-bridged TRIAZOLES Energetic materials High nitrogen compounds 
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