LYMPHOMAS

作品数：31被引量：45H指数：3
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相关作者：刘敏陈钢王俊阁艾建伟张春雷更多>>
相关机构：首都医科大学附属北京中医医院大连医科大学附属第二医院北京大学第三医院苏州大学更多>>
相关期刊：《World Journal of Clinical Oncology》《中国口腔颌面外科杂志》《Journal of Cancer Therapy》《World Journal of Dermatology》更多>>
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Discovery of a novel BTK inhibitor S-016 and identification of a new strategy for the treatment of lymphomas including BTK inhibitor-resistant lymphomas
《Acta Pharmacologica Sinica》2024年第10期2163-2173,共11页Pei-ran Song Zhi-peng Wan Ge-ge Huang Zi-lan Song Tao Zhang Lin-jiang Tong Yan Fang Hao-tian Tang Yu Xue Zheng-sheng Zhan Fang Feng Yan Li Wen-hao Shi Yu-qing Huang Yi Chen Wen-hu Duan Jian Ding Ao Zhang Hua Xi 
supported by High-level Innovative Research Institute,Department of Science and Technology of Guangdong Province(2021B0909050003);Zhongshan Municipal Bureau of Science and Technology(2023B2029);the National Natural Science Foundation of China(82273948);the Project of Shanghai Institute of Materia Medica,CAS(SIMM0120231001);State Key Laboratory of Drug Research(SKLDR-2023-TT-01);Institutes for Drug Discovery and Development,CAS(CASIMM0120225003-1 and-2).
Bruton’s tyrosine kinase(BTK)has emerged as a therapeutic target for B-cell malignancies,which is substantiated by the efficacy of various irreversible or reversible BTK inhibitors.However,on-target BTK mutations fac...
关键词：diffuse large B-cell lymphoma BTK inhibitors drug resistance BTK C481F BTK A428D SYHA1813 
Prevalence of malignant neoplasms in celiac disease patients-a nationwide United States population-based study
《World Journal of Clinical Oncology》2024年第8期1048-1060,共13页Maryam Bilal Haider Ali Al Sbihi Sushmitha Nanja Reddy Peter Green 
BACKGROUND Celiac disease(CeD)is an autoimmune disorder triggered by the immune response to gluten in genetically predisposed individuals.Recent research has unveiled a heightened risk of developing specific malignant...
关键词：Celiac disease Malignant neoplasm Autoimmune disorder Hospitalized patients Healthcare utilization Gastrointestinal malignancies LYMPHOMAS EPIDEMIOLOGY 
A retrospective analysis of mature T-and NK-cell lymphomas被引量：2
《Cancer Biology & Medicine》2024年第3期223-229,共7页Junlei Jia Xiaohui Wang Zheng Song Shen Meng Yue Fei Jingwei Yu Xia Liu Xue Han Lanfang Li Lihua Qiu Zhengzi Qian Shiyong Zhou Wenchen Gong Bin Meng Xiubao Ren Xianhuo Wang Huilai Zhang 
supported by the Construction Project of Cancer Precision Diagnosis and Drug Treatment Technology(Grant No. ZLJZZDYYWZL04);the Clinical Oncology Research Fund of CSCO(Grant No. Y-SY2021MS-0240);the Haihe Yingcai(Tianjin)Project(Grant No. TJSJMYXYC-D2-039);the Tianjin Key Medical Discipline(Specialty)Construction Project grant(Grant No. TJYXZDXK-009A);the CACA-BeiGene Lymphoma Research Foundation(Grant No.CORP-117)。
Mature T-and natural killer(NK)-cell lymphomas are heterogeneous groups of malignant lymphoid neoplasms arising from T and NK cells. The incidence of mature T-and NK-cell lymphomas is 2.1 per 100,000 people, according...
关键词：LYMPHOMA NEOPLASMS KILLER 
Composite B-cell and T-cell lymphomas:clinical,pathological,and molecular features of three cases and literature review被引量：3
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2023年第8期711-722,共12页Xueli JIN Hui LIU Jing LI Xibin XIAO Xianggui YUAN Panpan CHEN Boxiao CHEN Yun LIANG Fengbo HUANG 
supported by the Zhejiang Medical Health Science and Technology Project(No.2021KY166);the Natural Science Foundation of Zhejiang Province(No.LQ23H080003),China.
Composite lymphoma(CL)involving B-cell lymphoma and T-cell lymphoma is extremely rare.Herein,we report three such cases using immunohistochemistry,flow cytometry,and the next-generation sequencing(NGS)to identify the ...
关键词：Composite lymphoma B-cell lymphoma T-cell lymphoma 
Long noncoding RNAs (lncRNAs) in human lymphomas被引量：2
《Genes & Diseases》2022年第4期900-914,共15页Ali Gholami Khosro Farhadi Fatemeh Sayyadipour Masoud Soleimani Fakhredin Saba 
Lymphomas are a diverse group of haematologic malignancies, which occur in infection-fighting cells of the lymphatic system. Long non-coding RNAs (lncRNAs) are non-coding RNAs, which have recently received significant...
关键词：APOPTOSIS Long non-coding RNA LYMPHOMA PROGNOSIS PROLIFERATION 
Classification and Diagnosis of Lymphoma’s Histopathological Images Using Transfer Learning
《Computer Systems Science & Engineering》2022年第2期629-644,共16页Schahrazad Soltane Sameer Alsharif Salwa M.Serag Eldin 
Current cancer diagnosis procedure requires expert knowledge and is time-consuming,which raises the need to build an accurate diagnosis support system for lymphoma identification and classification.Many studies have s...
关键词：CLASSIFICATION confusion matrices deep learning k-fold cross validation lymphoma diagnosis residual neural network transfer learning 
Impact of the microenvironment on the pathogenesis of mucosaassociated lymphoid tissue lymphomas被引量：2
《World Journal of Gastrointestinal Oncology》2022年第1期153-162,共10页Barbara Uhl Katharina T Prochazka Karoline Fechter Katrin Pansy Hildegard T Greinix Peter Neumeister Alexander JA Deutsch 
Approximately 8%of all non-Hodgkin lymphomas are extranodal marginal zone B cell lymphomas of mucosa-associated lymphoid tissue(MALT),also known as MALT lymphomas.These arise at a wide range of different extranodal si...
关键词：Mucosa-associated lymphoid tissue lymphoma Tumor microenvironment MICROENVIRONMENT Helicobacter pylori Activated immune cells 
Mechanisms of resistance to FGFR1 inhibitors in FGFR1-driven leukemias and lymphomas:implications for optimized treatment被引量：3
《Cancer Drug Resistance》2021年第3期607-619,共13页John K.Cowell Tianxiang Hu 
This work was supported by a grant from the National Institutes of Health,CA076167。
Myeloid and lymphoid neoplasms with eosinophilia and FGFR1 rearrangements(MLN-eo FGFR1)disease is derived from a pluripotent hematopoietic stem cell and has a complex presentation with a myeloproliferative disorder wi...
关键词：MLN-eo FGFR1 LYMPHOMAS FGFR1 MUTATIONS PTEN PUMA mouse models 
Identification of Hub Genes and Key Pathways Associated with Peripheral T-cell Lymphoma被引量：1
《Current Medical Science》2020年第5期885-899,共15页Hai-xia GAO Meng-bo WANG Si-jing LI Jing NIU Jing XUE Jun LI Xin-xia LI 
The study was supported by grants from the National Natural Science Foundation of China(No.81660036);the Project of the Bingtuan Science and Technology(No.2019DB012).
Peripheral T-cell lymphoma(PTCL)is a very aggressive and heterogeneous hematological malignancy and has no effective targeted therapy.The molecular pathogenesis of PTCL remains unknown.In this study,we chose the gene ...
关键词：peripheral Tcell lymphomas bioinformatic analysis protein-protein interaction hub genes pathwayg 
Liquid biopsy in lymphomas: a potential tool for refining diagnosis and disease monitoring
《Journal of Cancer Metastasis and Treatment》2019年第9期20-27,共8页Riccardo Moia Chiara Favini Silvia Rasi Clara Deambrogi Valentina Ferri Mattia Schipani Sruthi Sagiraju Abdurraouf Mokhtar Mahmoud Ahad Ahmed Kodipad Ramesh Adhinaveni Andrea Patriarca Luca Nassi Gianluca Gaidano 
Work by the authors described in this review has been supported by Molecular bases of disease dissemination in lymphoid malignancies to optimize curative therapeutic strategies,(5 ′ 1000 21198);Associazione Italiana per la Ricerca sul Cancro Foundation Milan, Italy;Progetto Ricerca Finalizzata RF-2011-02349712, Ministero della Salute, Rome, Italy;PRIN 2015ZMRFEA_004, MIUR, Rome, Italy;AGING Project - Department of Excellence - DIMET, Università del Piemonte Orientale, Novara, Italy
Liquid biopsy consists in a simple blood sampling that allows to analyze cell free DNA (cfDNA), containing specific genomic clues released by the tumor into the bloodstream. In this review, we shall focus on the analy...
关键词：Liquid biopsy LYMPHOMA precision medicine 
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