MONOOXYGENASE

作品数：53被引量：68H指数：4
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相关领域：生物学农业科学更多>>
相关作者：李淑媛李华高广猷朱静雯蒋璐更多>>
相关机构：大连医科大学上海医科大学遵义医学院江苏省农业科学院更多>>
相关期刊：《Chinese Medical Journal》《Food Science and Human Wellness》《Systems Microbiology and Biomanufacturing》《Chinese Herbal Medicines》更多>>
相关基金：国家自然科学基金北京市自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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Cyt02 encodes cytochrome P450 monooxygenase,increasing rice(Oryza sativa L.)resistance to sheath blight被引量：1
《The Crop Journal》2025年第1期92-103,共12页Tengda Zheng Xiaolin Wang Yuewen He Deqiang Li Andrews Danso Ofori Xing Xiang Abdul Ghani Kandhro Xiaoqun Yi Fu Huang Jianqing Zhu Ping Li Aiping Zheng 
supported by the Sichuan Province International Science and Technology Innovation Cooperation(2024YFHZ0299);the Project of Science and Technology Department of Sichuan Province(2022YFH0031);Chengdu Science and Technology Bureau(2024-YF05-02168-SN).
Rice sheath blight(RSB)is a major destructive disease impeding rice production.Identifying key germplasm resources with increased resistance remains a challenge.However,the mechanisms underlying disease resistance are...
关键词：RICE Sheath blight Cytochrome P450 monooxygenase Metabolomics analysis Functional analysis 
Full biosynthetic pathway of pyrrolobenzoxazines
《Chinese Chemical Letters》2025年第1期433-436,共4页Kunya Wang Bingyu Liu Daojiang Yan Jian Bai Haibo Yu Youcai Hu 
supported financially by the National Natural Science Foundation of China(Nos.22107122 and 82225042);the CAMS Innovation Fund for Medical Sciences(CIFMS,No.2021I2M-1-029)。
Pyrrolobenzoxazines are a rare terpene-amino acid family of natural products with potent biological activities.Here,we reported the full biosynthetic pathway of paeciloxazine(1),a typical pyrrolobenzoxazine,with signi...
关键词：Pyrrolobenzoxazines Paeciloxazine BIOSYNTHESIS P450 monooxygenase Antiepileptic activity 
Establishing Modular Cell-Free Expression System for the Biosynthesis of Bicyclomycin from a Chemically Synthesized Cyclodipeptide
《Chinese Journal of Chemistry》2024年第4期384-390,共7页Yi-Pei Liu Yu-Heng Zhao Wen-Qi Zhang Lian Wu Linjuan Huang Gong-Li Tang Jun-Bin He 
supported in part by grants from the National Key Research and Development Program of China(2022YFC2303100);the National Natural Science Foundation of China(22207117).
Cell-free expression systems have emerged as a versatile and powerful platform for metabolic engineering,biosynthesis and synthetic biology studies.Nevertheless,successful examples of the synthesis of complex natural ...
关键词：Natural products Bicyclomycin BIOSYNTHESIS Iron-andα-ketoglutarate-dependent dioxygenases Cytochrome P450 monooxygenase Cell-freeprotein synthesis Enzyme catalysis 
Regioselective and enantioselective propargylic hydroxylations catalyzed by P450tol monooxygenases
《Bioresources and Bioprocessing》2024年第1期855-863,共9页Xu Deng Cheng-Cheng Song Wen-Jing Gu Yu-Jie Wang Lu Feng Xiao-Jian Zhou Ming-Qiang Zhou Wei-Cheng Yuan Yong-Zheng Chen 
financial support from the National Natural Science Foundation of China(No.32271537 and 22061049);the Science and Technology Department of Guizhou province(QKHJCZK2021-036 and QKHRCPTGCC-2023-003);the Science and Technology Department of Zunyi(ZSKRPT-2020-5,ZSKH-2018-3,ZSKRPT-2021-5);Zunyi Medical University(QKH-2018-5772-014).
Regioselective and enantioselective hydroxylation of propargylic C-H bonds are useful reactions but often lack appropriate catalysts.Here a green and efficient asymmetric hydroxylation of primary and secondary C-H bon...
关键词：BIOCATALYSIS HYDROXYLATION P450 monooxygenase Propargylic alcohols ENANTIOSELECTIVITY 
Development of a microbial dewaxing agent using three spore forming bacteria
《Bioresources and Bioprocessing》2024年第1期1063-1075,共13页Xiaoyan Guo Xutao Zhao Lizhu Li Haibo Jin Jianjun Wang 
the financial support from Scientific Research Program of Beijing Municipal Commission of Education(KM202110017009,granted to Xiaoyan Guo);Undergraduates Research Training Program of Beijing Institute of Petrochemical Technology(2022J00178,granted to Lizhu Li)。
Microbial enhanced oil recovery(MEOR)is a cost effective and efficient method for recovering residual oil.However,the presence of wax(paraffin)in residual oil can substantially reduce the efficiency of MEOR.Therefore,...
关键词：Alkane monooxygenase Microbial enhanced oil recovery Microbial wax removal agent SURFACTIN 
The function of steroid terminal monooxygenase in cholesterol or phytosterol degradation by the Mycobacterium neoaurum NRRL B‑3805
《Systems Microbiology and Biomanufacturing》2023年第4期585-592,共8页Xuemei Li Rui Zhang Jianjiong Li Jinhui Feng Qiaqing Wu Dunming Zhu Yanhe Ma 
supported by the National Key R and D Program of China(NO.2019YFA0905300);National Natural Science Foundation of China(No.32171477);Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(No.TSBICIP-KJGG-001 and TSBICIP-PTJJ-007).
Cholesterol and phytosterols can be served as the substrates for Actinobacteria to produce the precursors used in the synthesis of steroidal medicines.Cytochrome P450s from CYP125 and CYP142 families initiates the met...
关键词：Sterol degradation Mycobacterium neoaurum Steroid C26/C27 monooxygenase Cytochrome CYP125s and CYP142s 
Biosynthesis of trialkyl-substituted aromatic polyketide NFAT-133 involves unusual P450 monooxygenase-mediating aromatization and a putative metallo-beta-lactamase fold hydrolase
《Synthetic and Systems Biotechnology》2023年第3期349-356,共8页Ming Yang Wanlu Li Lin Zhou Xiao Lin Wenyu Zhang Yaoyao Shen Hai Deng Hou-wen Lin Yongjun Zhou 
the National Natural Science Foundation of China(Nos.32070070,32211530074 and 31929001);the innovative research team of high-level local universities in Shanghai.H.D.thanks Royal Society-NSFC international exchange grant(IEC\NSFC\211349).
The bacterial trialkyl-substituted aromatic polyketides are structurally featured with the unusual aromatic core in the middle of polyketide chain such as TM-123(1),veramycin A(2),NFAT-133(3)and benwamycin I(4),which ...
关键词：Thioesterase Metallo hydrolase METALLO-BETA-LACTAMASE Aromatic polyketide Polyketide synthase P450 monooxygenase 
Characterization of the P450 Monooxygenase LobP1 as C-32 Hydroxylase in Lobophorin Biosynthesis
《Chinese Journal of Chemistry》2023年第12期1478-1484,共7页Bin Tan Qingbo Zhang Ji Xiao Chengshan Yuan Yuchan Chen Siqiang Chen Weimin Zhang Yiguang Zhu Changsheng Zhang 
supported in part by the National Natural Science Foundation of China(22193072 and 32100045);the Key Science and Technology Project of Hainan Province(ZDKJ202018);MOST(2018YFA0901903);K.C.WongEducationnFoundation(GJTD-2020-12);the Guangdong Provincial Special Fund for Marine Economic Development Project(GDNRC[2021]48);the Science and Technology Planning Project of Guangzhou(202102020471);Rising Star Foundation of the South China Sea Institute of Oceanology(NHXX2018SW0201)。
Lobophorins(LOBs)belong to a large family of spirotetronate antibiotics with antibacterial and antitumor activities.In this study,we demonstrated the function of LobP1,a P450 monooxygenase encoded in the LOB biosynthe...
关键词：Lobophorins BIOSYNTHESIS Post modifications P450 monooxygenase HYDROXYLATION Enzymes Biological activity Structure elucidation 
Kynurenine pathway of tryptophan metabolism in pathophysiology and therapy of major depressive disorder被引量：1
《World Journal of Psychiatry》2023年第4期141-148,共8页Abdulla A-B Badawy Shazia Dawood Samina Bano 
Serotonin deficiency in major depressive disorder(MDD)has formed the basis of antidepressant drug development and was originally attributed to induction of the major tryptophan(Trp)-degrading enzyme,liver Trp 2,3-diox...
关键词：Major depressive disorder Indoleamine 2 3-dioxygenase Kynurenine monooxygenase Proinflammatory cytokines Serotonin deficiency Tryptophan 2 3-dioxygenase 
Recent advances in the efficient degradation of lignocellulosic metabolic networks by lytic polysaccharide monooxygenase
《Acta Biochimica et Biophysica Sinica》2023年第4期529-539,共11页Xinran Yu Yue Zhao Junhong Yu Lushan Wang 
the grants from the Key Research and Development Program of Shandong Province(No.2021CXGC010803);Open Research Fund of State Key Laboratory of Biological Fermentation Engineering of Beer(No.2450021011).
Along with long-term evolution,the plant cell wall generates lignocellulose and other anti-degradation barriers to confront hydrolysis by fungi.Lytic polysaccharide monooxygenase(LPMO)is a newly defined oxidase in lig...
关键词：phylogenetic classification redox partner cosubstrate structural proteomics metabolic network 
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