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COFACTOR: 作品数：50被引量：72H指数：4; 导出分析报告; 相关领域：生物学医药卫生更多>>; 相关作者：焦士会刘林初芹钱丽颖王祥民更多>>; 相关机构：北京奶牛中心新疆维吾尔自治区畜牧总站中国农业大学新疆农业大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金广东省自然科学基金制浆造纸工程国家重点实验室开放基金国家现代农业产业技术体系建设项目更多>>

Peptide bridging for cofactor channeling in fusion enzyme lowers cofactor input by two orders of magnitude: 《Chinese Journal of Catalysis》2025年第4期390-403,共14页Zehui Guo Yan Sun; 国家重点研发计划(2018YFA0900702).; Biocatalysis with nicotinamide adenine dinucleotide phosphate(NADP)-dependent oxidoreductases faces a challenge in improving the efficiency of the costly cofactor utilization.Although enzyme fusion can offer cofactor ...; 关键词：Peptide bridge Fusion enzyme NADP(H)-dependent oxidoreductases Cofactor channeling Cofactor regeneration

Enhanced cofactor recycling and accelerated reaction rate via liquid-liquid phase separation in dual-enzyme condensates: 《Chinese Journal of Catalysis》2025年第2期135-148,共14页Jiaxu Liu Jiaxin Chen Xiaoyan Zhang Daidi Fan Yunpeng Bai; 国家重点研发计划(2023YFA0913600);国家自然科学基金(22378120,22078096)。; Enzyme catalysis is a promising way to produce chiral products in a green and sustainable way.However,the high cost of cofactors and their relatively low recycling efficiency hinder the widespread application of enzym...; 关键词：Cofactor recycling CONDENSATE Proximity effect Intrinsically disordered region Enzyme catalysis

Extensions of the Graham-Hoffman-Hosoya Type Theorems for the Exponential Distance Matrices and q-Distance Matrices: 《Journal of Mathematical Research with Applications》2024年第6期723-734,共12页Jie WANG; Let G be a strongly connected directed weighted graph with vertex set{v_(1),v_(2),...,v_(n)},in which each edge e is assigned with an arbitrary nonzero weight w(e).For any two vertices v_i,v_(j )of G,the distance d_(i...; 关键词：distance matrices exponential distance matrices q-distance matrices determinants COFACTORS cofactor sums

Double-stranded DNA-nucleic acid dye complex-sensitized biocatalytic photosynthesis:Base pairing-switched regeneration of nicotinamide cofactor: 《Journal of Energy Chemistry》2024年第7期618-624,共7页Zhen Dong Yanying Wang Dan Li Peng Wu; the financial support from the National Natural Science Foundation of China (22274102 and 22325403);the Fundamental Research Funds from Sichuan University (2022SCUNL104);the Open Research Fund of School of Chemistry and Chemical Engineering,Henan Normal University(2022A02); Photo-biocatalysis,the combination of photosensitization and biocatalysis,is an emerging solution for sunlight-based renewable energy.It is thus important to develop light antennas with both good light har-vesting and...; 关键词：PHOTOSYNTHESIS DSDNA SYBRGreenI TICT 2-phenylpropanol

Engineering of cofactor preference and catalytic activity of methanol dehydrogenase by growth-coupled directed evolution被引量：2: 《Green Carbon》2024年第2期242-251,共10页Jinxing Yang Liwen Fan Guimin Cheng Tao Cai Jibin Sun Ping Zheng Shuang Li Yu Wang; supported by the Strategic Priority Research Program of the Chinese Academy of Sciences(XDC0110201);the National Key R&D Program of China(2018YFA0901500);the National Natural Science Foundation of China(32070083 and 32222004);the Innovation Fund of Haihe Laboratory of Synthetic Biology(22HHSWSS00017);the Youth Innovation Promotion Association of Chinese Academy of Sciences(2021177);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-008).; Methanol,produced from carbon dioxide,natural gas,and biomass,has drawn increasing attention as a promising green carbon feedstock for biomanufacturing due to its sustainable and energy-rich properties.Nicotinamide ad...; 关键词：Growth-coupled screening Methanol dehydrogenase Cofactor engineering Directed evolution C1 bioconversion

Copper-radical oxidases: A diverse group of biocatalysts with distinct properties and a broad range of biotechnological applications: 《Engineering Microbiology》2022年第3期23-36,共14页Katja Koschorreck Saadet Alpdagtas Vlada B.Urlacher; This work was supported by the Ministry of Innovation,Science and Research the state of North Rhine-Westphalia,Germany within the framework of the NRW-Strategieprojekt BioSC(No.313/323-400-00213);together with the“European Regional Development Fund(EFRE)”,Project“Clus-ter Industrial Biotechnology(CLIB)Kompetenzzentrum Biotechnologie(CKB)”(34.EFRE-0300095/1703FI04);Financial support by the Scien-tific and Technological Research Council of Turkey(TUBITAK)2219-International Research Fellowship Programme for Saadet Alpdagtas is gratefully acknowledged.; Copper-radical oxidases(CROs)catalyze the two-electron oxidation of a large number of primary alcohols includ-ing carbohydrates,polyols and benzylic alcohols as well as aldehydes and𝛼-hydroxy-carbonyl compounds while...; 关键词：Copper-radical oxidases Galactose oxidase Glyoxal oxidase Cysteine-tyrosyl radical cofactor Carbohydrates Alcohols Aldehydes

Improved L -phenylglycine synthesis by introducing an engineered cofactor self-sufficient system: 《Synthetic and Systems Biotechnology》2022年第1期513-521,共9页Pengchao Wang Xiwen Zhang Yucheng Tao Xubing Lv Shengjie Cheng Chengwei Liu; the National Natural Science Foundation of China(Project No.31900064);as well as the Natural Science Foundation of Heilongjiang Province of China(Project No.LH2019C012)。; L-phenylglycine(L-phg)is a valuable non-proteinogenic amino acid used as a precursor to β-lactam antibiotics,antitumor agent taxol and many other pharmaceuticals.L-phg synthesis through microbial bioconversion allows...; 关键词：L-phenylglycine Whole-cell biocatalyst Self-sufficient Protein scaffold Hydroxymandelate synthase

Modules for in vitro metabolic engineering:Pathway assembly for biobased production of value-added chemicals被引量：5: 《Synthetic and Systems Biotechnology》2017年第2期65-74,共10页Hironori Taniguchi Kenji Okano Kohsuke Honda; Research in our laboratory was supported in part by the Japan Science and Technology Agency(PRESTO,CREST,and A-STEP programs)and the Japan Society for the Promotion of Science(KAKENHI program).; Bio-based chemical production has drawn attention regarding the realization of a sustainable society.In vitro metabolic engineering is one of the methods used for the bio-based production of value-added chemicals.This...; 关键词：In vitro metabolic engineering Module GLYCOLYSIS Pentose phosphate pathway Cofactor management

Conformational conversion of prion protein in prion diseases被引量：3: 《Acta Biochimica et Biophysica Sinica》2013年第6期465-476,共12页Zheng Zhou Gengfu Xiao; Funding This work was supported by the grants from the National Natural Science Foundation of China （No. 30970150 and No. 31170156）.; Prion diseases are a group of infectious fatal neurodegenerative diseases. The conformational conversion of a cellular prion protein （PrPc） into an abnormal misfolded isoform （PrPso） is the key event in prion dise...; 关键词：prion disease prion protein conformationalconversion COFACTOR

Bivariate Splines and Golden Section Based on Theory of Elasticity: 《Journal of Mathematical Research and Exposition》2011年第1期1-11,共11页Ren Hong WANG Jin Cai CHANG; Supported by the National Natural Science Foundation of China (Grant Nos. 60533060;60373093;10726068);the Natural Science Foundation of Hebei Province (Grant Nos. A2009000735;A2010000908);Research Projectof Hebei Educational Committee (Grant No.2009448);Shanghai Key Laboratory for Contemporary AppliedMathamtics (Grant No.09FG067); Splines are important in both mathematics and mechanics. We investigate the relationships between bivariate splines and mechanics in this paper. The mechanical meanings of some univariate splines were viewed based on ...; 关键词：multivariate spline smoothing cofactor conformality condition bending of thin plate golden section.

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