supported by the National Key Research and Development Program(2022YFC2402900);the Key Research and Development Program of Hainan Province(ZDYF2024SHFZ128);the Science and Technology Innovation Program of Hunan Province(2022RC1213),China.
Objective:Drug-loaded mucoadhesive silk fibroin(SF)microneedle patch can overcome the limitations of low bioavailability and significant pain associated with traditional treatment methods,such as topical application o...
National Research Foundation of Korea,Grant/Award Numbers:2023-00208913,RS-2023-00208262。
Colorectal cancer is one of the most common cancers,and current treatment options include surgery,chemotherapy,and radiation therapy.Most patients undergo surgery,which often requires extensive resection of the colon ...
The authors regret that there was a picture error in Fig.8.In Fig.8B,a copy mistake of H&E photographs was made when combining the images of different groups.The revisions do not affect any results and conclusions of ...
supported by the International Postdoctoral Exchange Fellowship Program(Grant No.20190060)。
Mucins are vital components contributing to the unique lubrication properties of human whole saliva.For patients receiving medication and or treatment such as diabetes or radiotherapy,xerostomia(dry mouth)is a common ...
supported by the National Natural Science Foundation of China(No.81903811);China Postdoctoral Science Foundation(No.2021M690488);National TCM Multidisciplinary Interdisciplinary Innovation Team Project:Multidisciplinary Evaluation of Southwest Characteristic TCM Resources Multidisciplinary Interdisciplinary Innovation Team(No.ZYYCXTD-D-202209)。
Although multitudinous nanoscale drug-delivery systems(DDSs)have been recommended to improve anti-ulcerative colitis(UC)outcomes,to enhance the mucoadhesion of nanosystems on the colon and specifically release the loa...
This research work deals with formulation and evaluation of nanosized Tiagabine loaded bio-flexy films consisting of Cocos nucifera biopolymer(isolated from coconut kernels).Prepared formulations were administered thr...
financially supported by National Science and Technology Major Project of China(Grant Nos.2018ZX09721003 and 2018ZX09711001)
Efficient mucosal delivery remains a major challenge for the reason of the respiratory tract mucus act as a formidable barrier to nanocarriers by trapping and clearing foreign particulates. The surface property of nan...
The study was financially supported by the National Natural Science Foundation of China(Grant Nos.51973216,51873207,51833010,and 51803006);the Science and Technology Development Program of Jilin Province(Grant No.20200404182YY);the Youth Innovation Promotion Association of Chinese Academy of Sciences(Grant No.2019005).
Intravesical chemotherapy has been recommended after the gold standard of transurethral resection of the bladder tumor to prevent bladder cancer(BC)from local recurrence in the clinic.However,due to rapid urine excret...
Cashew gum is a branched chain heteropolysaccharide extracted from the cashew tree (Anacardium occidentale L.).Purified cashew gum (PCG) is free of plant contaminants and is highly soluble.Several studies have indicat...
A sericin/alginate blend was successfully applied as a matrix for incorporation of ibuprofen.This provided a sustained release formulation,which could improve the therapeutic efficacy of ibuprofen and patient adherenc...