MUCOADHESIVE

作品数:24被引量:42H指数:3
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相关领域:医药卫生化学工程更多>>
相关期刊:《Journal of Biomedical Research》《Journal of Physical Science and Application》《Asian Journal of Pharmaceutical Sciences》《中南大学学报(医学版)》更多>>
相关基金:国家自然科学基金中国博士后科学基金国家重点基础研究发展计划更多>>
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Pre-assembled nanospheres in mucoadhesive microneedle patch for sustained release of triamcinolone in the treatment of oral submucous fibrosis
《中南大学学报(医学版)》2024年第8期1245-1260,共16页CHENG Xian YANG Yanqing HUANG Junming GUO Qiuyun ZHU Wei LONG Dingpei ZHOU Yueying FENG Hui WANG Jie LI Yusi ZHOU Jian LIU Yanping LIU Ousheng 
supported by the National Key Research and Development Program(2022YFC2402900);the Key Research and Development Program of Hainan Province(ZDYF2024SHFZ128);the Science and Technology Innovation Program of Hunan Province(2022RC1213),China.
Objective:Drug-loaded mucoadhesive silk fibroin(SF)microneedle patch can overcome the limitations of low bioavailability and significant pain associated with traditional treatment methods,such as topical application o...
关键词:oral disease oral mucosal disease oral submucous fibrosis mucoadhesive microneedle patch 
Mucoadhesive and antifouling Janus polysaccharide film for prevention of colorectal cancer recurrence post-surgery
《BMEMat(BioMedical Engineering Materials)》2024年第2期134-144,共11页Jaebeom Lee Hee Seung Seo Chun Gwon Park Mikyung Shin 
National Research Foundation of Korea,Grant/Award Numbers:2023-00208913,RS-2023-00208262。
Colorectal cancer is one of the most common cancers,and current treatment options include surgery,chemotherapy,and radiation therapy.Most patients undergo surgery,which often requires extensive resection of the colon ...
关键词:ANTIFOULING colon cancer MUCOADHESIVE polysaccharide film 
Author correction to‘Amino-functionalized poloxamer 407 with both mucoadhesive and thermosensitive properties:Preparation,characterization and application in vaginal drug delivery system'[Acta Pharm Sin B 7(2017)593-602]
《Acta Pharmaceutica Sinica B》2023年第9期3961-3962,共2页Li-qian Ci Zhi-gang Huang Yu Liu Zhe-peng Liu Gang Wei Wei-yue Lu 
The authors regret that there was a picture error in Fig.8.In Fig.8B,a copy mistake of H&E photographs was made when combining the images of different groups.The revisions do not affect any results and conclusions of ...
关键词:application CORRECTION system 
Stable oral lubrication enhancer obtained from thiolated polyethylene glycol and mucin
《Friction》2023年第4期617-634,共18页Xiaoyan HE Pravin SMART Mohamad TAUFIQURRAKHMAN Chun WANG Michael BRYANT 
supported by the International Postdoctoral Exchange Fellowship Program(Grant No.20190060)。
Mucins are vital components contributing to the unique lubrication properties of human whole saliva.For patients receiving medication and or treatment such as diabetes or radiotherapy,xerostomia(dry mouth)is a common ...
关键词:LUBRICATION MUCIN polyethylene glycol MUCOADHESIVE CHEMISORPTION 
Oral colon-targeted mucoadhesive micelles with enzyme-responsive controlled release of curcumin for ulcerative colitis therapy被引量:3
《Chinese Chemical Letters》2022年第11期4924-4929,共6页Chen Zhang Jiaxin Li Meng Xiao Di Wang Yan Qu Liang Zou Chuan Zheng Jinming Zhang 
supported by the National Natural Science Foundation of China(No.81903811);China Postdoctoral Science Foundation(No.2021M690488);National TCM Multidisciplinary Interdisciplinary Innovation Team Project:Multidisciplinary Evaluation of Southwest Characteristic TCM Resources Multidisciplinary Interdisciplinary Innovation Team(No.ZYYCXTD-D-202209)。
Although multitudinous nanoscale drug-delivery systems(DDSs)have been recommended to improve anti-ulcerative colitis(UC)outcomes,to enhance the mucoadhesion of nanosystems on the colon and specifically release the loa...
关键词:CURCUMIN Enzyme-responsive Micelles MUCOADHESION Ulcerative colitis 
Preparation and evaluation of mucoadhesive bio-flexy films from Cocos nucifera biopolymer using Tiagabine moiety
《Precision Medicine Research》2021年第4期4-15,共12页Sugandha Varshney N.V.Satheesh Madhav 
This research work deals with formulation and evaluation of nanosized Tiagabine loaded bio-flexy films consisting of Cocos nucifera biopolymer(isolated from coconut kernels).Prepared formulations were administered thr...
关键词:Nanosized Tiagabine Soft palatal delivery MUCOADHESIVE Cocos nucifera BIOPOLYMER Bio-flexy films 
Comparative study of mucoadhesive and mucus-penetrative nanoparticles based on phospholipid complex to overcome the mucus barrier for inhaled delivery of baicalein被引量:1
《Acta Pharmaceutica Sinica B》2020年第8期1576-1585,共10页Wujun Dong Jun Ye Junzhuo Zhou Weijue Wang Hongliang Wang Xu Zheng Yanfang Yang Xuejun Xia Yuling Liu 
financially supported by National Science and Technology Major Project of China(Grant Nos.2018ZX09721003 and 2018ZX09711001)
Efficient mucosal delivery remains a major challenge for the reason of the respiratory tract mucus act as a formidable barrier to nanocarriers by trapping and clearing foreign particulates. The surface property of nan...
关键词:sustained MUCUS BARRIER 
Synergistically Enhanced Mucoadhesive and Penetrable Polypeptide Nanogel for Efficient Drug Delivery to Orthotopic Bladder Cancer被引量:10
《Research》2020年第1期1659-1672,共14页Hui Guo Faping Li Heping Qiu Weiguo Xu Pengqiang Li Yuchuan Hou Jianxun Ding Xuesi Chen 
The study was financially supported by the National Natural Science Foundation of China(Grant Nos.51973216,51873207,51833010,and 51803006);the Science and Technology Development Program of Jilin Province(Grant No.20200404182YY);the Youth Innovation Promotion Association of Chinese Academy of Sciences(Grant No.2019005).
Intravesical chemotherapy has been recommended after the gold standard of transurethral resection of the bladder tumor to prevent bladder cancer(BC)from local recurrence in the clinic.However,due to rapid urine excret...
关键词:BLADDER CHEMOTHERAPY DISULFIDE 
Pre-formulation Study for Preparation of Mucoadhesive Buccal Tablets Containing Nystatin and Cashew Gum by Direct Compression
《Journal of Physical Science and Application》2019年第1期1-14,共14页Ana Paula de SáPinto Abrahao Magalhaes Flávia Almada do Carmo Claudia Regina Elias Mansur 
Cashew gum is a branched chain heteropolysaccharide extracted from the cashew tree (Anacardium occidentale L.).Purified cashew gum (PCG) is free of plant contaminants and is highly soluble.Several studies have indicat...
关键词:Purified cashew gum NYSTATIN mucoadhesive buccal tablets 
Development of mucoadhesive sericin/alginate particles loaded with ibuprofen for sustained drug delivery
《Particuology》2018年第6期65-73,共9页Emanuelle D.Freitas Jacyara M.M.Vidart Edson A.Silva Meuris G.C.da Silva Melissa G.A.Vieira 
A sericin/alginate blend was successfully applied as a matrix for incorporation of ibuprofen.This provided a sustained release formulation,which could improve the therapeutic efficacy of ibuprofen and patient adherenc...
关键词:SERICIN ALGINATE IBUPROFEN SUSTAINED DRUG release 
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