云南高校图书馆联盟文献共享服务平台- MUCUS

MUCUS: 作品数：85被引量：320H指数：10; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：韩德民王琪张罗林桂芳冯睿智更多>>; 相关机构：浙江师范大学首都医科大学华中科技大学四川大学华西医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金北京市科技新星计划国家重点基础研究发展计划国家高技术研究发展计划更多>>

Dietary oxidized cholesterol causes mucus barrier thinner via decreasing Muc2 expression in the proximal colon and increasing the abundance of mucus-degrading bacteria: 《Food Science and Human Wellness》2025年第4期1251-1263,共13页Chi Yan Shouhe Huang Zixing Chen Huafang Ding Zhenyu Chen; supported by Hong Kong Research Grants Council General Research Fund(CUHK 14102321,14103722 and 14104923)。; Oxidized cholesterol(OXC)is a harmful dietary substance.Although the consumption of OXC has been associated with colonic inflammation,related underlying mechanisms are still limited.We evaluated the influence of dieta...; 关键词：Dietary oxidized cholesterol Gut microbiota Colonic inflammation Mucus barrier Western diets Inflammatory bowel diseases

Dynamic mucus secretion in ventral surfaces of toe pads of the tree frog (Dryophytes japonica): 《Integrative Zoology》2024年第6期1076-1091,共16页Jae-Uk SEOL Jung Su PARK Jae-Hong LIM Hyeon Su HWANG Eun-Bin KIM Seob-Gu KIM Jae-Il PARK Ha-Cheol SUNG Joon Heon KIM Eung-Sam KIM; supported by a National Research Foundation of Korea grant funded by the Korean government(MSIT)(Grant Nos.2022R1A2C1007366 and 2021R1A2C1008787).; The tree frog is a prominent amphibian among terrestrial vertebrates known for its ability to adhere to various surfaces through the capillary forces of water in the microchannels between micropillars on its disc-shap...; 关键词：interference reflection microscopy mucus pore mucus secretion synchrotron X-ray microtomography toe pad tree frog

Mucus provisioning as milk in an amphibian: 《Integrative Zoology》2024年第5期1014-1016,共3页Xiaohan SANG Shichang ZHANG; supported by a grant from the National Natural Science Foundation of China(32370530).; Parental care is a trait that shows tremendous diversity both within and across various animal taxa,constituting a focal point in evolutionary biology and behavioral ecology(Royle et al.2012;Kappeler 2022).It forms an...; 关键词：PROVISION EVOLUTIONARY showing

Functional PEGylated bacteria reinforce the intestinal mucosal barrier by effective mucus-penetration: 《Science Bulletin》2024年第19期2964-2966,共3页Xinyuan Yang Zhonglin Fang Luoran Shang; supported by the National Key Research and Development Program of China(2020YFA0908200);the National Natural Science Foundation of China(32271383).; Recently,the intestinal mucosal barrier has attracted considerable attention from the scientific community.With the in-depth exploration of this barrier,it has become increasingly clear that the mucosal barrier is a c...; 关键词：MUCOSAL INVASION barrier

Inhaled multilevel size-tunable,charge-reversible and mucus-traversing composite microspheres as trojan horse:Enhancing lung deposition and tumor penetration: 《Chinese Chemical Letters》2024年第9期273-278,共6页Lishan Xiong Xinyuan Li Xiaojie Lu Zhendong Zhang Yan Zhang Wen Wu Chenhui Wang; supported by the National Natural Science Foundation of China(No.52273123);the Natural Science Foundation of Chongqing,China(No.CSTB2022NSCQ-MSX0474);the Talent-introduction Program of Chongqing Medical and Pharmaceutical College(No.YGZRC2023103).; Dry powder inhalation represents a promising approach for the treatment of lung cancer,offering several advantages such as enhanced targeting,improved bioavailability,and reduced toxicity.However,traditional dry powde...; 关键词：Pulmonary delivery Size-tunable nanoparticles Charge-reversible nanoparticles Mucus penetration Lung cancer

PEGylated bacteria restore intestinal mucosal barrier: 《Acta Pharmaceutica Sinica B》2024年第9期4186-4188,共3页Menghang Zu Xue Xia Bo Xiao; the National Natural Science Foundation of China(82072060).; The mucosal barrier of the gastrointestinal tract(GIT)is crucial for the overall health of the body.Its disruption permits the infiltration of intestinal microorganisms into the underlying mucosa,resulting in infectio...; 关键词：PEGYLATION Probiotic Mucus penetration Colonic mucosal barrier COLITIS Diabetes

Abelmoschus manihot polysaccharide fortifies intestinal mucus barrier to alleviate intestinal inflammation by modulating Akkermansia muciniphila abundance被引量：1: 《Acta Pharmaceutica Sinica B》2024年第9期3901-3915,共15页Yumeng Wang Chengxi Li Jianping Li Shu Zhang Qinyu Zhang Jinao Duan Jianming Guo; the National Natural Science Foundation of China(82074136);High level key discipline construction project of the National Administration of Traditional Chinese Medicine-Resource Chemistry of Chinese Medicinal Materials(No.zyyzdxk-2023083,China).; The intestinal mucus barrier is an important line of defense against gut pathogens.Damage to this barrier brings bacteria into close contact with the epithelium,leading to intestinal inflammation.Therefore,its restora...; 关键词：Plant polysaccharide Abelmoschus manihot Intestinal inflammation Mucus barrier Interleukin 10 Gut microbiota A.muciniphila Mucin 2

Damage on intestinal barrier function and microbial detoxification of deoxynivalenol:A review: 《Journal of Integrative Agriculture》2024年第8期2507-2524,共18页Jia Chen Xinran Zhang Ziqi He Dongwei Xiong Miao Long; funded by the National Natural Science Foundation of China(32273074,31972746,31872538 and 31772809);the Basic Scientific Research Project of Liaoning Provincial Department of Education,China(LJKZ0632)。; Deoxynivalenol(DON)is a mycotoxin that is produced by various species of Fusarium and is ubiquitous in food and feed.At low concentrations,it can cause metabolic disorders in animals and humans and,at high concentrati...; 关键词：deoxynivalenol(DON) intestinal barrier function mucus barrier immune function flora composition biological detoxification

The crucial role of fish mucus in regulating progeny inflammation and microbial homeostasis: 《Water Biology and Security》2024年第2期31-45,共15页Zi-Xuan Wang Hao-Yue Xu Qiu-Lu He Yong-Yao Yu Zhen Xu; supported by grants from the National Natural Science Foundation of China(32225050,32073001)to Z.X.; Maternal immunity plays a vital role in protecting offspring from pathogen invasion,and it is present in nearly all vertebrates.As the most ancient vertebrates,teleost fish continuously secrete a substantial amount of...; 关键词：MUCUS Maternal immunity Inflammatory response Dextran sulfate sodium(DSS) ZEBRAFISH

Worm-like micelles facilitate the intestinal mucus diffusion and drug accumulation for enhancing colorectal cancer therapy被引量：1: 《Chinese Chemical Letters》2024年第6期427-432,共6页Yihan Zhou Duo Gao Yaying Wang Li Liang Qingyu Zhang Wenwen Han Jie Wang Chunliu Zhu Xinxin Zhang Yong Gan; the financial support from the National Natural Science Foundation of China(Nos.82003678,82222066,82025032);Chinese Pharmacopoeia Commission(No.2021Y30)。; Local delivery of nanoparticles holds promise for colorectal cancer(CRC)therapy.However,the presence of the mucus layer on the epithelium poses a significant challenge to drug delivery,thereby adversely affecting trea...; 关键词：Worm-like micelles Mucus penetration Shape dependent Transmucosal delivery Colorectal cancer

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