PHARMACOKINETIC

作品数:198被引量:425H指数:10
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相关作者:程远国王艺林玮玮王琰肇丽梅更多>>
相关机构:军事医学科学院山东大学河北医科大学首都医科大学附属北京天坛医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金河北省自然科学基金更多>>
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  • 期刊=Journal of Biosciences and Medicinesx
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Bioequivalence of Two Formulations of Metformin Hydrochloride 1000 mg XR Tablets, Fasting Condition in Healthy Adults Subjects
《Journal of Biosciences and Medicines》2024年第12期411-423,共13页Evelyn Pena Alfredo Inatti Anyoly Taly José Chacón Xenon Serrano-Martin 
Background: This study aimed to evaluate the bioequivalence of the two formulations of metformin 1000 mg XR tablets in healthy male volunteers under fasting conditions. Methods: This was a randomized, single-dose, ope...
关键词:BIOEQUIVALENCE METFORMIN PHARMACOKINETIC 
A Bioequivalence Study of Empagliflozin/Metformin Fixed-Dose Combination in Healthy Subjects under Fasting Conditions
《Journal of Biosciences and Medicines》2024年第9期235-250,共16页Evelyn Pena Alfredo Inatti Anyoly Taly José Chacón Xenon Serrano-Martin 
Background: This study evaluated the bioequivalence of empagliflozin 12.5 mg/metformin 1000 mg tablets compared to Synjardy® (Empagliflozin 12.5 mg/metformin 1000 mg) tablets in healthy male subjects under fasting con...
关键词:BIOEQUIVALENCE Fix Dose Combinations PHARMACOKINETIC Empagliflozin 
Pharmacokinetic Comparison and Bioequivalence Evaluation of Two 20-mg Vonoprazan Fumarate Tablets in Bangladeshi Healthy Male Subjects
《Journal of Biosciences and Medicines》2024年第8期230-243,共14页Md. Alimur Reza Uttom Kumar Bhowmik Sabrina Akter Tushi Nayan Ghosh Nithon Chandra Sahana Md. Ashraful Islam Nafisa Ahamed Arifa Akram 
Background: Vonoprazan fumarate, a novel potassium-competitive acid blocker, outperforms traditional proton pump inhibitors in acid suppression and can be effectively combined with antibiotics to eradicate Helicobacte...
关键词:BIOEQUIVALENCE Vonoprazan Pharmacokinetics 
The Presence of Phases and the Inability of the Classical Compartment Models to Provide Pharmacokinetic Parameters of Physiological Significance for Lipophilic Drugs
《Journal of Biosciences and Medicines》2022年第4期1-13,共13页Michalakis Savva 
The first biphasic open one-compartment pharmacokinetic model is described. Its analytical solutions to drug concentration were developed from parameters of an open two-compartment pharmacokinetic model. The model is ...
关键词:Lipophilic Drugs Pharmacokinetic Compartment Model Apparent Volume of Distribution Clearance PRAZOSIN DOXAZOSIN DIGOXIN PINDOLOL 
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