PRAZOSIN

作品数：17被引量：16H指数：2
导出分析报告
相关领域：医药卫生更多>>
相关作者：李森王丽华涂植光张亚松张玲更多>>
相关机构：同济大学重庆医科大学东南大学南通医学院更多>>
相关期刊：《Acta Pharmacologica Sinica》《Pharmacology & Pharmacy》《Neural Regeneration Research》《胃肠病学》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划陕西省教育厅科研计划项目更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-10
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
The Presence of Phases and the Inability of the Classical Compartment Models to Provide Pharmacokinetic Parameters of Physiological Significance for Lipophilic Drugs
《Journal of Biosciences and Medicines》2022年第4期1-13,共13页Michalakis Savva 
The first biphasic open one-compartment pharmacokinetic model is described. Its analytical solutions to drug concentration were developed from parameters of an open two-compartment pharmacokinetic model. The model is ...
关键词：Lipophilic Drugs Pharmacokinetic Compartment Model Apparent Volume of Distribution Clearance PRAZOSIN DOXAZOSIN DIGOXIN PINDOLOL 
A Reevaluation of Prazosin Pharmacokinetics in a Two-Compartment Model, the Apparent Volume of Distribution and Comparative Simulations in the One-Compartment Model被引量：2
《Journal of Biosciences and Medicines》2022年第1期108-140,共33页Michalakis Savva Xudong Yuan 
Published clinical data of Prazosin were reevaluated pharmacokinetically using explicit solutions to drug concentration as a function of total time for IV bolus injection, intermittent intravenous infusion and oral ro...
关键词：PRAZOSIN PHARMACOKINETICS Intravenous Bolus Intermittent Infusion Oral Dose Multiple Doses Compartment Model Apparent Volume of Distribution 
α1-AR overactivation induces cardiac inflammation through NLRP3 inflammasome activation被引量：5
《Acta Pharmacologica Sinica》2020年第3期311-318,共8页Jun-zhou Xin Ji-min Wu Guo-min Hu Hui-jun Gu Ye-nan Feng Shuai-xing Wang Wen-wen Cong Ming-zhe Li Wen-li Xu Yao Song Han Xiao You-yi Zhang Li Wang 
This work was supported by grants from the National Natural Science Foundation of China(81260028 to Li Wang,No.81530009 to You-yi Zhang and No.81670205 to Han Xiao);the Fund for Fostering Young Scholars of Peking University Health Science Center(No.BMU2017PY016 to Han Xiao);the Open Foundation from Beijing Key Laboratory of Hypertension Research(No.2017GXY-KFKT-05 to Han Xiao).
Acute sympathetic stress causes excessive secretion of catecholamines and induces cardiac injuries,which are mainly mediated byβ-adrenergic receptors(β-ARs).However,α1-adrenergic receptors(α1-ARs)are also expresse...
关键词：α1-adrenergic RECEPTOR CARDIAC INFLAMMATION NOD-like RECEPTOR protein 3 INFLAMMASOME caspase-1 interleukin-18 PHENYLEPHRINE PRAZOSIN 
The fate of prazosin and levonorgestrel after electrochemical degradation process: Monitoring by-products using LC-TOF/MS被引量：1
《Journal of Environmental Sciences》2018年第12期134-146,共13页Fouad Fadhil Al-Qaim Zainab Haider Mussa Ali Yuzir Jalifah Latip Mohamed Rozali Othman 
Universiti Kebangsaan Malaysia for the scholarship of Z. H. Mussa (matric No. p69014)
Prazosin（PRZ） and levonorgestrel（LNG） are widely used as an anti-disease drugs due to their biological activity in the human body. The frequent detection of these compounds in water samples requires alternative te...
关键词：PRAZOSIN LEVONORGESTREL Electrochemical degradation Solid phase extraction Chlorinated by-products TOXICITY 
Primary prevention of posttraumatic stress disorder: drugs and implications被引量：1
《Military Medical Research》2015年第3期156-162,共7页Joachim C Burbiel 
Because posttraumatic stress disorder(PTSD) is a highly debilitating condition, prevention is an important research topic. This article reviews possible prevention approaches that involve the administration of drugs b...
关键词：Posttraumatic stress disorder Prevention Pre-treatment PROPRANOLOL PRAZOSIN KETAMINE MORPHINE ANISOMYCIN Osanetant 
Insights into cardio-oncology:Polypharmacology of quinazoline-based α1-adrenoceptor antagonists
《World Journal of Cardiology》2015年第5期238-242,共5页Salvatore Patanè 
New uses of cardiovascular drugs with proven experience are emerging,including for treating cancer.Quinazoline is a compound made up of two fused six member simple aromatic rings,benzene and pyrimidine rings,with seve...
关键词：Cardio-oncology Multidrug resistance PRAZOSIN TERAZOSIN Doxazosin 
Prazosin:a potential new management tool for iatrogenic autonomic dysreflexia in individuals with spinal cord injury?被引量：1
《Neural Regeneration Research》2015年第4期557-558,共2页Mei M.Z.Zheng Aaron A.Phillips Stacy L.Elliott Andrei V.Krassioukov 
AAP is supported by the Heart and Stroke Foundation of Canada;the Michael Smith Foundation for Health Research;AVK is supported by the Paralyzed Veterans of America;the Craig Neilson Foundation;the Canadian Institute of Health Research;the Heart and Stroke Foundation of Canada
Spinal cord injury （SCI） is a devastating condition that not only results in a loss of motor functions but also severe autonomic dysfunctions （Krassioukov and Claydon, 2006）. Autonomic dysreflexia （AD） is a life...
关键词：PRAZOSIN SCI AD DBP 
Activity Induced by a Naphthalene-Prazosin Derivative on Ischemia/Reperfusion Injury in Rats
《Pharmacology & Pharmacy》2014年第12期1130-1142,共13页Betty Sarabia-Alcocer Lauro Figueroa-Valverde Francisco Díaz-Cedillo Lenin Hau-Heredia Marcela Rosas-Nexticapa Elodia García-Cervera Eduardo Pool-Gómez Rolando García-Martínez Braulio Zepeda-Acosta 
In this study, a new naphthalene-prazosin derivative (compound 5) was synthetized with the objective of evaluating its activity on ischemia/reperfusion injury. The Langendorff technique was used to evaluate the effect...
关键词：PRAZOSIN LEFT VENTRICULAR Pressure NIFEDIPINE NAPHTHALENE 
Method for quantification of prazosin in dog plasma and its application to pharmacokinetic study
《Journal of Southeast University(English Edition)》2011年第2期217-221,共5页张妮萍 余书勤 王辉 申艳艳 徐师 张玲 许茜 
Pre-Research Foundation for the National Natural Science Foundation of Southeast University(No.9225000007);Suzhou Science and Technology Development Projects(No.YJS0948)
A simple and sensitive high performance liquid chromatography method using fluorescence detection （HPLC- FLD） and a one-step single solvent extraction for the determination of prazosin（PZS） in dog plasma is develo...
关键词：prazosin （ PZS ） PZS-sulfobutyl ether beta-cyclodextrin （PZS-SBE-[3-CD） inclusion complex tablets highperformance liquid chromatography （HPLC） pharmacokinetics 
Internalization and distribution of three α_1-adrenoceptor subtypes in HEK293A cells before and after agonist stimulation
《Acta Pharmacologica Sinica》2007年第3期359-366,共8页Shu-yi WANG Yao SONG Ming XU Qi-hua HE Qi-de HAN You-yi ZHANG 
Project supported by the National Key Basic Research Program of the People's Republic of China(No G2000056906);the National Natural Science Foundation of China(No 30490172,30171083).
Aim： To examine the subcellular distribution of the 3 α1-adrenoceptor （α1-AR） subtypes and their internalization and trafficking upon agonist stimulation in human embryonic kidney 293A cells. Methods： Confocal r...
关键词：ADRENOCEPTOR agonist stimulation confocalimage enzyme-linked immunosorbent assay [3H]-prazosin binding assay INTERNALIZATION subcellular distribution subtype 
全选清除导出
共2页<12>
检索报告 对象比较 聚类工具 使用帮助 返回顶部