PHENYLEPHRINE

作品数：29被引量：45H指数：4
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相关领域：医药卫生更多>>
相关作者：郭永娟王锐杨顶建祁元明杨帆更多>>
相关机构：兰州大学国立中兴大学大连医科大学南京医科大学更多>>
相关期刊：《Journal of Diabetes Mellitus》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Pharmacology & Pharmacy》更多>>
相关基金：国家自然科学基金广东省自然科学基金国家重点基础研究发展计划更多>>
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Small molecule QF84139 ameliorates cardiac hypertrophy via activating the AMPK signaling pathway
《Acta Pharmacologica Sinica》2022年第3期588-601,共14页Xu-xia Li Peng Zhang Yang Yang Jing-jing Wang Yan-jun Zheng Ji-liang Tan Shen-yan Liu Yong-ming Yan You-yi Zhang Yong-xian Cheng Huang-tian Yang 
This work was supported by the National Natural Science Foundation of China(81770402,81520108004 to H-tY),Strategic Priority Research Program of the CAS(No.XDA16010201 to HTY);National Key R&D Program of China(2017YFA0103700 to HTY);the research funding from Shanghai Jiao Tong University Affiliated Sixth People’s Hospital to HTY and National Science Fund for Distinguished Young Scholars(81525026 to YXC).
Cardiac hypertrophy is a common adaptive response to a variety of stimuli,but prolonged hypertrophy leads to heart failure.Hence,discovery of agents treating cardiac hypertrophy is urgently needed.In the present study...
关键词：cardiac hypertrophy pyrazine derivative QF84139 PHENYLEPHRINE transverse aortic constriction AMPK signaling pathway 
6-Gingerol protects against cardiac remodeling by inhibiting the p38 mitogen-activated protein kinase pathway被引量：2
《Acta Pharmacologica Sinica》2021年第10期1575-1586,共12页Shu-qing Ma Zhen Guo Fang-yuan Liu Shahzad-Gul Hasan Dan Yang Nan Tang Peng An Ming-yu Wang Hai-ming Wu Zheng Yang Di Fan Qi-zhu Tang 
The present study was supported by grants from the National Natural Science Foundation of China(81900219,81530012,and 81800216);the Fundamental Research Funds for the Central Universities(2042019kf0062 and 2042018kf1032);the Development Center for Medical Science and Technology National Health and Family Planning Commission of China(2016ZX-008-01);the National Key R&D Program of China(2018YFC1311300).
6-Gingerol,a pungent ingredient of ginger,has been reported to possess anti-inflammatory and antioxidant activities,but the effect of 6-gingerol on pressure overload-induced cardiac remodeling remains inconclusive.In ...
关键词：6-GINGEROL pressure overload cardiac remodeling mitogen-activated protein kinase p38 CARDIOMYOCYTES cardiac fibroblasts PHENYLEPHRINE TGF-β 
Perioperative risk factors associated with delayed graft function following deceased donor kidney transplantation:A retrospective,single center study被引量：2
《World Journal of Transplantation》2021年第4期114-128,共15页Nicholas V Mendez Yehuda Raveh Joshua J Livingstone Gaetano Ciancio Giselle Guerra George W Burke III Vadim B Shatz Fouad G Souki Linda J Chen Mahmoud Morsi Jose M Figueiro Tony M Ibrahim Werviston L DeFaria Ramona Nicolau-Raducu 
BACKGROUND There is an abundant need to increase the availability of deceased donor kidney transplantation(DDKT)to address the high incidence of kidney failure.Challenges exist in the utilization of higher risk donor ...
关键词：Delayed graft function OUTCOME Kidney transplant Risk factors PHENYLEPHRINE Mean arterial pressure 
α1-AR overactivation induces cardiac inflammation through NLRP3 inflammasome activation被引量：5
《Acta Pharmacologica Sinica》2020年第3期311-318,共8页Jun-zhou Xin Ji-min Wu Guo-min Hu Hui-jun Gu Ye-nan Feng Shuai-xing Wang Wen-wen Cong Ming-zhe Li Wen-li Xu Yao Song Han Xiao You-yi Zhang Li Wang 
This work was supported by grants from the National Natural Science Foundation of China(81260028 to Li Wang,No.81530009 to You-yi Zhang and No.81670205 to Han Xiao);the Fund for Fostering Young Scholars of Peking University Health Science Center(No.BMU2017PY016 to Han Xiao);the Open Foundation from Beijing Key Laboratory of Hypertension Research(No.2017GXY-KFKT-05 to Han Xiao).
Acute sympathetic stress causes excessive secretion of catecholamines and induces cardiac injuries,which are mainly mediated byβ-adrenergic receptors(β-ARs).However,α1-adrenergic receptors(α1-ARs)are also expresse...
关键词：α1-adrenergic RECEPTOR CARDIAC INFLAMMATION NOD-like RECEPTOR protein 3 INFLAMMASOME caspase-1 interleukin-18 PHENYLEPHRINE PRAZOSIN 
Bolus norepinephrine and phenylephrine for maternal hypotension during elective cesarean section with spinal anesthesia:a randomized,double-blinded study被引量：10
《Chinese Medical Journal》2020年第5期509-516,共8页Xian Wang Mao Mao Su-Su Zhang Zhao-Hui Wang Shi-Qin Xu Xiao-Feng Shen 
Background:In recent years,norepinephrine has attracted increasing attention for the management of maternal hypotension during elective cesarean section with spinal anesthesia.Intermittent bolus is a widely used admin...
关键词：NOREPINEPHRINE PHENYLEPHRINE Cardiac output CESAREAN section 
Effects of ephedrine, phenylephrine and norepinephrine prevent hypotension after spinal anesthesia in cesarean section and comparison of effects on newborns
《Journal of Hainan Medical University》2019年第3期65-68,共4页Li-Xia Huang Shao-Nong Huang Ze-Wei Wu 
Objective: To compare the preventive effect of ephedrine, phenylephrine and norepinephrine on hypotension after lumbar anesthesia in cesarean section and their effects on newborns. Methods: 25 cesarean section women i...
关键词：EPHEDRINE PHENYLEPHRINE NOREPINEPHRINE Cesarean section HYPOTENSION AFTER spinal anesthesia Newborn 
Differential effects of short- and long-term bupivacaine treatment on α1-adrenoceptor-mediated contraction of isolated rat aorta rings and the reversal effect of lipid emulsion被引量：1
《Acta Pharmacologica Sinica》2015年第8期976-986,共11页Hao GUO He-feiZHANG Wen-qi XU Qian DU Jing ZHAO Lei-ming REN 
Aim： Arterial function is significantly influenced by bupivacaine at both clinically relevant concentrations and toxic concentrations, but the underlying mechanisms are not fully understood. In the present study we i...
关键词：BUPIVACAINE aortic rings α1-adrenoceptors PHENYLEPHRINE VASOCONSTRICTION ACETYLCHOLINE VASODILATION lipids emulsions local anesthetics 
Recombinant streptokinase vs phenylephrine-based suppositories in acute hemorrhoids, randomized, controlled trial(THERESA-3)被引量：4
《World Journal of Gastroenterology》2014年第6期1594-1601,共8页Francisco Hernández-Bernal Georgina Castellanos-Sierra Carmen M Valenzuela-Silva Karem M Catasús-lvarez Roselin Valle-Cabrera Ana Aguilera-Barreto Pedro A López-Saura 
Supported by Heber Biotec,Havana(products,reagents) and the Ministry of Public Health of Cuba(hospital facilities and general medical care of the patients)
AIM: To compare the efficacy and safety of recombinant streptokinase (rSK) and phenylephrine-based suppositories in acute hemorrhoidal disease.
关键词：STREPTOKINASE SUPPOSITORY PHENYLEPHRINE THROMBOLYSIS HEMORRHOIDS Randomized clinical trial 
Effect of administration of phenylephrine immediately after low dose insemination on pregnancy rates in mares
《Open Journal of Obstetrics and Gynecology》2013年第10期722-726,共5页Theresa Beachler Renan Sper C. Scott Bailey James Shewmaker C. Nick Buchanan Anne Josson-Schramme Michael Whitacre 
There is considerable pressure on equine veterinarians to achieve good pregnancy rates with very small doses of semen. Phenylephrine administration in the rabbit increased numbers of oviductal, uterine, and cervical s...
关键词：Artificial INSEMINATION Low DOSE INSEMINATION EQUINE PHENYLEPHRINE 
Antioxidant Protective Effects of the Resveratrol on the Cardiac and Vascular Tissues from Renal Hypertensive Rats
《Open Journal of Medicinal Chemistry》2012年第3期61-71,共11页Joyce Cristina de Oliveira Carla Renata Kitanish Antonietto Angélica Cristina Scalabrini Talita Sanches Marinho Larissa Pernomian JoséWilson NCorrêa Carolina Baraldi Araujo Restini 
Background: Accumulating reactive oxygen species (ROS) is involved in cellular signaling and function disturbances due to the oxidative stress, which contributes to several diseases. The consequences of ROS activity r...
关键词：HYPERTENSION AORTA Superoxide RESVERATROL PHENYLEPHRINE Reactive Species of Oxygen(ROS) 
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