INTEROCEPTION

作品数：7被引量：12H指数：2
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Skeletal interoception and prospective application in biomaterials for bone regeneration
《Bone Research》2025年第1期1-14,共14页Long Bai Jilong Li Guangfeng Li Dongyang Zhou Jiacan Su Changsheng Liu 
National Natural Science Foundation of China(82230071,82172098);Integrated Project of Major Research Plan of National Natural Science Foundation of China(92249303);Shanghai Committee of Science and Technology(23141900600,Laboratory Animal Research Project);Shanghai Clinical Research Plan of SHDC2023CRT01;Young Elite Scientist Sponsorship Program by China Association for Science and Technology(YESS20230049)。
Accumulating research has shed light on the significance of skeletal interoception,in maintaining physiological and metabolic homeostasis related to bone health.This review provides a comprehensive analysis of how ske...
关键词：HOMEOSTASIS BIOMATERIALS utilize 
Skeletal interoception in osteoarthritis
《Bone Research》2024年第2期241-254,共14页Dinglong Yang Jiawen Xu Ke Xu Peng Xu 
supported by the National Natural Science Foundation of China(82072432).
The interoception maintains proper physiological conditions and metabolic homeostasis by releasing regulatory signals after perceving changes in the internal state of the organism.Among its various forms,skeletal inte...
关键词：HOMEOSTASIS INFLAMMATION RELEASING 
Brain regulates weight bearing bone through PGE2 skeletal interoception: implication of ankle osteoarthritis and pain被引量：2
《Bone Research》2024年第1期107-121,共15页Feng Gao Qimiao Hu Wenwei Chen Jilong Li Cheng Qi Yiwen Yan Cheng Qian Mei Wan James Ficke Junying Zheng Xu Cao 
This research was supported by NIH National Institute on Aging under Award Number R01 AG076783,R01 AG068997 and P01 AG066603(to X.C.).
Bone is a mechanosensitive tissue and undergoes constant remodeling to adapt to the mechanical loading environment.However,it is unclear whether the signals of bone cells in response to mechanical stress are processed...
关键词：PAIN ELEVATED PGE2 
PGE2/EP4 skeleton interoception activity reduces vertebral endplate porosity and spinal pain with low-dose celecoxib被引量：6
《Bone Research》2021年第3期396-409,共14页Peng Xue Shenyu Wang Xiao Lyu Mei Wan Xialin Li Lei Ma Neil CFord Yukun Li Yun Guan Wenyuan Ding Xu Cao 
supported by National Institute on Aging of the National Institutes of Health under Award Number R01 AG068997 and P01 AG066603(to X.C.).
Skeletal interoception regulates bone homeostasis through the prostaglandin E2(PGE2)concentration in bone.Vertebral endplates undergo ossification and become highly porous during intervertebral disc degeneration and a...
关键词：pain DOSAGE IMPAIRED 
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