CONDUIT

作品数：112被引量：275H指数：8
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A novel flexible nerve guidance conduit promotes nerve regeneration while providing excellent mechanical properties
《Neural Regeneration Research》2025年第7期2084-2094,共11页Tong Li Quhan Cheng Jingai Zhang Boxin Liu Yu Shi Haoxue Wang Lijie Huang Su Zhang Ruixin Zhang Song Wang Guangxu Lu Peifu Tang Zhongyang Liu Kai Wang 
supported by the National Natural Science Foundation of China,No.82202718;the Natural Science Foundation of Beijing,No.L212050;the China Postdoctoral Science Foundation,Nos.2019M664007,2021T140793(all to ZL)。
Autografting is the gold standard for surgical repair of nerve defects>5 mm in length;however,autografting is associated with potential complications at the nerve donor site.As an alternative,nerve guidance conduits m...
关键词：aligned fibers anti-kinking helical fibers nerve guidance conduit nerve regeneration peripheral nerve injury topological guidance 
A semi-analytical model of the velocity profile for a conduit-multilayer matrix system
《Journal of Rock Mechanics and Geotechnical Engineering》2025年第2期915-930,共16页Shuai Zhang Xiaoli Liu Enzhi Wang 
financially supported by the National Natural Science Foundation of China(Grant Nos.52079068,52090081);the State Key Laboratory of Hydroscience and Engineering(Grant No.2021-KY-04).
The flow field characteristics of the conduit-matrix system(CMS)have consistently been a primary area of interest to researchers.However,under the long-term influence of water flow,the hydraulic conductivity of the ma...
关键词：Flow field characteristics Velocity profile Conduit aperture Stress jumping Conduit-matrix system(CMS) 
Enhancement of anti-PD-L1 antibody plus anlotinib efficacy due to downregulation of PD-L1 in the micro-conduit endothelium within the tumor:a randomized double-blind trial
《Cancer Biology & Medicine》2024年第10期951-962,共12页Cuicui Zhang Tianqing Chu Qiming Wang Ying Cheng Yongxiang Zhang Ruili Wang Leilei Ma Chaonan Qian Baohui Han Kai Li 
Objective:The possible enhancing effect of anlotinib on programmed death receptor ligand(PD-L1)antibody and the efficacy-predicting power of PD-L1 in micro-conduit endothelium,including lymphatic endothelial cells(LEC...
关键词：PD-L1 lymphatic endothelial cell blood endothelial cell anlotinib progression-free survival 
Human umbilical cord mesenchymal stem cell-derived exosomes loaded into a composite conduit promote functional recovery after peripheral nerve injury in rats被引量：4
《Neural Regeneration Research》2024年第4期900-907,共8页Haoshuai Tang Junjin Li Hongda Wang Jie Ren Han Ding Jun Shang Min Wang Zhijian Wei Shiqing Feng 
supported by the National Key Research and Development Project of Stem Cell and Transformation Research,No.2019YFA0112100(to SF);the National Natural Science Foundation of China No.81930070(to SF);Multi-fund Investment Key Projects,No.21JCZDJC01100(to ZW);the Tianjin Science and Technology Planning Project,No.22JRRCRC00010(to SF)。
Complete transverse injury of peripheral nerves is challenging to treat.Exosomes secreted by human umbilical cord mesenchymal stem cells are considered to play an important role in intercellular communication and regu...
关键词：axon growth collagen EXOSOME human umbilical cord mesenchymal stem cells hyaluronic acid muscular atrophy nerve guidance conduits peripheral nerve regeneration 
An unusual cause of cyanosis after intra-extra cardiac Fontan procedure: anastomotic leakage between conduit and inferior vena cava
《World Journal of Pediatric Surgery》2023年第4期282-284,共3页Jiajun Xu Weize Xu Jin Yu Shanshan Shi Qiang Shu Zhuo Shi 
funded by Young Doctor Research Project of Zhejang University(grant number:2021FzZX005-06).
A child aged 7 years was admitted to our hospital nearly 5 years after an intra-extra cardiac Fontan operation due to aggravated cyanosis.He was diagnosed with pulmonary atresia(PA),atrial septal defect,patent ductus ...
关键词：admitted CARDIAC SEPTAL 
Air bubble breakup in shear water flows generated by a plug conduit:An experimental investigation
《Journal of Hydrodynamics》2023年第6期1077-1088,共12页Han Wu Mao-lin Zhou Wei-lin Xu Wang-ru Wei Jian-bo Li 
supported by the National Natural Science Foundation of China(Grant Nos.52192673,51979182).
In the context of a sudden contraction plug conduit,the near-wall area experiences a significant shearing effect of water flow,however,the extent to which this shearing effect occurs in bubble-water flow and the relat...
关键词：Air-water flows bubble properties air diffusion process plug conduits experimental study 
Li-Mg-Si bioceramics provide a dynamic immuno-modulatory and repair-supportive microenvironment for peripheral nerve regeneration被引量：3
《Bioactive Materials》2023年第10期227-242,共16页Yiting Sun Hongjian Zhang Yu Zhang Zheqi Liu Dongming He Wanlin Xu Siyi Li Chenping Zhang Zhen Zhang 
supported by a grant from the National Natural Science Foundation of China(81900968);Shanghai Sailing Program(20YF1409900);Shanghai Anticancer Association EYAS PROJECT(SACA-CY21A01 and SACA-CY22A01).
Biomaterials can modulate the local immune and repair-supportive microenvironments to promote peripheral nerve regeneration. Inorganic bioceramics have been widely used for regulating tissue regeneration and local imm...
关键词：Peripheral nerve regeneration BIOCERAMICS Immuno-modulation microenvironment MACROPHAGE Nerve guidance conduit 
Explosion Event of Cavitation in Intact Xylem Conduit
《Journal of Applied Mathematics and Physics》2023年第10期2803-2315,共13页Xingyue Li Fanyi Shen Tiqiao Xiao Yanling Xue Li Zhang Rongfu Gao Qian Zhang 
Cavitation in plant conduits only involves two processes of air bubbles: the gradual expansion and elongation, and the explosion event. An explosion event of cavitation, which can only occur in intact conduit at water...
关键词：Synchrotron X-Ray Phase Contrast Microscopy Explosion Event CAVITATION Intact Conduit 
Chitosan conduits enriched with fibrin-collagen hydrogel with or without adipose-derived mesenchymal stem cells for the repair of 15-mm-long sciatic nerve defect被引量：2
《Neural Regeneration Research》2023年第6期1378-1385,共8页Marwa El Soury óscar Darío García-García Isabella Tarulli Jesús Chato-Astrain Isabelle Perroteau Stefano Geuna Stefania Raimondo Giovanna Gambarotia Víctor Carriel 
funded by the Spanish “Plan Nacional de Investigación Científica, Desarrollo e Innovación Tecnológica, Ministerio de Economía y Competitividad (Instituto de Salud Carlos Ⅲ),grants Nos. FIS PI14-1343, FIS PI17-0393, and FIS PI20-0318 co-financed by the “Fondo Europeo de Desarrollo Regional ERDF-FEDER European Union”;grant No. P18-RT-5059 by “Plan Andaluz de Investigación, Desarrollo e Innovación (PAIDI 2020),Consejería de Transformación Económica, Industria, Conocimiento y Universidades, Junta de Andalucía, España”;grant No. A-CTS-498-UGR18 by “Programa Operativo FEDER Andalucía 2014–2020, Universidad de Granada, Junta de Andalucía, España”, co-funded by ERDF-FEDER, the European Union (all to VC)
Hollow conduits of natural or synthetic origins have shown acceptable regeneration results in short nerve gap repair;however,results are still not comparable with the current gold standard technique“autografts”.Holl...
关键词：adipose-derived stem cells chitosan conduit fibrin and collagen hydrogel nerve regeneration nerve repair neuregulin 1 peripheral nerve sciatic nerve 
Spinal cord conduits for spinal cord injury regeneration被引量：1
《Engineered Regeneration》2023年第1期68-80,共13页Yanyu Ma Quanchi Chen Wenhan Li Haiwen Su Song Li Yitong Zhu Jie Zhou Zhenhua Feng Zhen Liu Saihu Mao Yong Qiu Huan Wang Zezhang Zhu 
supported by National Natural Science Foundation of China (81972029;82102637);China Post-doctoral Science Foundation (2021M701675);Jiangsu Province 333 Talent Grant (2016-III-0114);Jiangsu commission of health (K2019009);Guangdong Basic and Applied Basic Research Foundation (2019A1515111155);the Shenzhen Fundamental Research Program (JCYJ20190808120405672);Public Health and Welfare Research Project of Futian District of Shenzhen (FTWS2022013).
Spinal cord injury(SCI),which causes irreversible damage in both sensory and motor function,is considered an insurmountable challenge in the field of medicine.The previous researchers have developed many kinds of biom...
关键词：Spinal cord injury Neuron regeneration Hydrogel Spinal cord conduit Tissue engineering 
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