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PLURIPOTENT: 作品数：144被引量：456H指数：9; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：朱露露石德顺李兰玉黄奔刘治威更多>>; 相关机构：中国科学院上海生命科学研究院广西大学内蒙古医科大学《科技导报》编辑部更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划广东省自然科学基金更多>>

TGF-β signaling pathway in induced pluripotent stem cells reprogramming: 《Chinese Medical Journal》2024年第18期2263-2265,共3页Weiwen Fan Heling Yuan Le Chang Qiang Li Jing Gao Lihua Ma Lvzhe Chen Ying Dai Xinghua Pan Xiangqing Zhu; supported by grants from the Key Projects in Yunnan Province(No.202301AY070001-034);the Project of the Yunnan Provincial Department of Education(No.2023Y0827); To the Editor:The discovery of the induced pluripotent stem cells(iPSCs)by Takahashi and Yamanaka in 2006 was hailed as a major breakthrough in stem cell research.And a large number of experimental studies have proven...; 关键词：programming. PROGRAMMING PLURIPOTENT

Correction to:Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells: 《Protein & Cell》2024年第5期393-393,共1页; This is a correction to:Chen Ling,Zunpeng Liu,Moshi Song,Weiqi Zhang,Si Wang,Xiaoqian Liu,Shuai Ma,Shuhui Sun,Lina Fu,Qun Chu,Juan Carlos Izpisua Belmonte,Zhaoxia Wang,Jing Qu,Yun Yuan,Guang-Hui Liu,Modeling CADASIL v...; 关键词：CADASIL PATIENT PLURIPOTENT

Distinct enhancer-promoter modes determine Sox2 regulation in mouse pluripotent cells: 《Genes & Diseases》2024年第1期26-29,共4页Lei Huang Xiusheng Zhu Qing Li Dashuai Kong Qitong Huang Jing Luo Siyuan Kong Yanling Peng Yubo Zhang; supported by the National Key Research and Development Program of China(No.2018YFA0903201);the National Natural Science Foundation of China(No.32202653 and 31970592);the Agricultural Science and Technology Innovation Program(33-AGIS-07);the China Postdoctoral Science Foundation(No.BX2021367 and 2021M703543);the Guangdong Basic and Applied Basic ResearchFoundation(No.2022A1515010766);the Shenzhen Science and Technology Program(No.KCXFZ2020122-1173205015 and RCBS20210609104512021).; Sox2 is a key transfer factor for maintaining pluripotency and self-renewal in embryonic stem cells(ESCs),1 though the mechanism of its transcriptional regulation in ESCs has not been fully addressed.Distal enhancer-p...; 关键词：SOX2 REGULATION DISTAL

A rational consideration of the genomic instability of human-induced pluripotent stem cells for clinical applications被引量：2: 《Science China(Life Sciences)》2023年第9期2198-2200,共3页Hang Zhang Zi-Bing Jin; Induced pluripotent stem cells (i PSCs) have gained popularity in regenerative medicine because of their ability to replicate and differentiate into multiple cell types, which has provided researchers with a powerful ...; 关键词：PLURIPOTENT DISEASES RATIONAL

Bionic Microbubble Neutrophil Composite for InflammationResponsive Atherosclerotic Vulnerable Plaque Pluripotent Intervention被引量：2: 《Research》2022年第3期105-115,共11页Fangfang Liu Yang Mao Jiaqi Yan Yu Sun Zhihua Xie Fei Li Fei Yan Hongbo Zhang Pengfei Zhang; the National Natural Science Foundation of China(nos.82071939,82030051,81571689,and 81871472);Research Fellow(grant no.328933),Solutions for Health Profile(336355);InFLAMES Flagship(337531)projects from Academy of Finland,as well as the Finland China Food and Health International Pilot Project funded by the Finnish Ministry of Education and Culture;grant from Shenzhen Basic Research Program(no.JCYJ20200109114825064).; Rupture or erosion of inflammatory atherosclerotic vulnerable plaque is essential to acute coronary events,while the target intervene of vulnerable plaque is very challenging,due to the relatively small volume,high he...; 关键词：BUBBLE holds utilize

Blockading a new NSCLC immunosuppressive target by pluripotent autologous tumor vaccines magnifies sequential immunotherapy被引量：3: 《Bioactive Materials》2022年第7期223-238,共16页Hong Wu Hongyan Li Yiqiang Liu Jingchen Liang Qianshi Liu Zhigang Xu Zhongzhu Chen Xia Zhang Kun Zhang Chuan Xu; This work was supported by the National Natural Science Foundation of China(82022033,81873048,81771836 and 82004006);Sichuan Provincial Science Fund for applied basic research of China(2020YJ0108);Sichuan Provincial Science Fund for Distinguished Young Scholars of China(2020JDJQ0065).; The presence of multiple immunosuppressive targets and insufficient activation and infiltration of cytotoxic T lymphocytes(CTLs)allow tumor cells to escape immune surveillance and disable anti-PD-1/PD-L1 immunotherapy...; 关键词：Autologous tumor vaccines(ATVs) Sequential immunotherapy Immunosuppressive microenvironment Tumor tropism Immune escape target

Islet organoid as a promising model for diabetes被引量：7: 《Protein & Cell》2022年第4期239-257,共19页Xiaofei Zhang Zhuo Ma Eli Song Tao Xu; This work was supported by grants from the Ministry of Science and Technology of the People’s Republic of China(2018YFA0507101,2016YFA0500203);the National Natural Science Foundation of China(31770900,31730054);the Beijing Natural Science Foundation(5212016);the Youth Innovation Promotion Association of the Chinese Academy of Sciences(2011087).; Studies on diabetes have long been hampered by a lack of authentic disease models that,ideally,should be unlimited and able to recapitulate the abnormalities involved in the development,structure,and function of human...; 关键词：islet organoid DIABETES pluripotent/adult stem cell pancreaticβcell disease model

In memory of Hal E.Broxmeyer,a pluripotent scientist,pioneer,and mentor: 《Blood Science》2022年第1期1-4,共4页Linzhao Cheng Bin Guo Xinxin Huang Tao Cheng; With great sadness,we residing in China heard the news that Professor Hal E.Broxmeyer passed away on December 8,2021,due to complications of thyroid cancer.He was 77.We regret that we could not say goodbye in person t...; 关键词：hundreds YOUNGER CONTINUE

Insight into generation of induced mesenchymal stem cells from induced pluripotent cells被引量：1: 《World Journal of Stem Cells》2022年第1期142-145,共4页Mahmood S Choudhery Ruhma Mahmood; Mesenchymal stem cells(MSCs)have the potential for use in cell-based regenerative therapies.Currently,hundreds of clinical trials are using MSCs for the treatment of various diseases.However,MSCs are low in number in ...; 关键词：Induced mesenchymal stem cells Induced pluripotent stem cells Regenerative potential PLURIPOTENT MULTIPOTENT Clinical studies

Perspective: Is It Time to Rename MSC (Mesenchymal Stem Cells/Medicinal Signaling Cells) with a Name that Reflects Their Combined <i>In Vivo </i>Functions and Their <i>In Vitro </i>Abilities?—Possibly “Pluripotent Mesenchymal Regulatory Cells (PMRC)”: 《Journal of Biomedical Science and Engineering》2021年第8期317-324,共8页David A. Hart; Over 30 years ago, it was reported by Caplan that cells could be found in various adult tissues and fluids of a variety of species that could be induced in vitro to progress towards lineages such as chondroge...; 关键词：Mesenchymal Stem Cells Medicinal Signaling Cells Pluripotent Cells Pluripotent Mesenchymal Regulatory Cells

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