supported by the grant to Chunyu Zeng from the National Key R&D Program of China(2022YFA1104500);the National Natural Science Foundation of China(82200307);the grant to Chunyu Zeng from the National Natural Science Foundation of China(81930008).
The formation of new and functional cardiomyocytes requires a 3-step process:dedifferentiation,proliferation,and redifferentiation,but the critical genes required for efficient dedifferentiation,proliferation,and redi...
supported by grants from the Training Program of the Major Research Plan of the National Natural Science Foundation of China (91857110);the National Key Research and Development Programme of China (2018YFA0800403 and 2016YFC1305303);the National Natural Science Foundation of China (81670740);the National Natural Science Fund for Excellent Young Scholars of China (81722012);the Zhejiang Provincial Natural Science Foundation of China (LZ21H070001);the Innovative Institute of Basic Medical Sciences of Zhejiang University, and the Fundamental Research Funds for the Central Universities, the Construction Fund of Medical Key Disciplines of Hangzhou (No. OO20200055);the Hangzhou Science and Technology Bureau (20150733Q13 and ZD20200129);the support from K.C. Wong Education Foundation
Type 2 diabetes(T2D)is caused by insulin resistance and insufficient insulin secretion.Evidence has increasingly indicated that pancreaticβ-cell dysfunction is the primary determinant of T2D disease progression and r...
supported by grants from the National Natural Science Foundation of China(81972503 and 82103656).
Anaplastic thyroid cancer(ATC)is a rare but highly lethal disease.ATCs are resistant to standard therapies and are extremely difficult to manage.The stepwise cell dedifferentiation results in the impairment of the iod...
Spathoglottis plicata Blume. is a horticulturally important vulnerable ground orchid with beautiful flowers blooming round the year. Highfrequency protocorm-like body(PLB) formation was established via callus culture ...
Supported by China Hunan Provincial Science&Technology Department(2012NK3118)~~
Based on selecting MS minimal medium, through changing the concentrations and additive amounts of two plant growth regulators of NAA and BA, the redifferentiation experiments of plant morphology on callus and embryos ...
Supported by Grants from the"Associazione Italiana Ricerche sul Cancro"
Studies on rodents and humans demonstrate an inherited predisposition to hepatocellular carcinoma (HCC). Analysis of the molecular alterations involved in the acquisition of a phenotype resistant or susceptible to h...
the Ministry of Science and Technology of China(2007CB948200);the National Natural Science Foundation of China(30770217)
Plant mature cells have the capability to reverse their state of differentiation and produce new organs under cultured conditions. Two phases, dedifferenUation and redifferentiation, are commonly characterized during ...
Objective To find out the mechanisms of redifferentiation and reversion of malignant human gastric cancer cells induced by ascorbic acid. Methods Human gastric cancer cells grown in the laboratory were used. The Trypa...
In vitro regeneration systems of Atrichum mosses, Atrichurn undulatum (Hedw.) P. Beauv. and A. undulatum var. minus (Hedw.) Par. were established. After one month, soft, friable and green calli were induced successful...
Objective To explore the effects and mechanisms of ascorbic acid (AA) and sodium selenite (SS) on growth inhibition and redifferentiation in human gastric cancer cells. Methods In the present study, trypan blue dye...