PROSTANOIDS

作品数:4被引量:11H指数:2
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Pharmacological evaluation of a novel enhydrazone ester (CEE-1) as a dual inhibitor of the release of pro-inflammatory cytokines and prostanoids from human monocytes
《Advances in Bioscience and Biotechnology》2013年第8期54-63,共10页Charles I. Ezeamuzie Hanan Zamil Hawraa Al-Baghli Ivan O. Edafiogho 
CEE-1 (ethyl 4-phenylhydrazinocyclohex-3-en-2-oxo-6-phenyl-1-oate)—a novel enhydrazone ester, was tested in vitro for anti-inflammatory activity against the release of pro-inflammatory cytokine and prostanoid from li...
关键词:Enhydrazone ESTER PROSTAGLANDIN E2 MONOCYTE Anti-Inflammatory Tumor NECROSIS FACTOR-ALPHA Cytokines 
Differential Effects of Angiotensin II on Intra-Renal Hemodynamics in Rats;Contribution of Prostanoids, NO and K<sup>+</sup>Channels
《Pharmacology & Pharmacy》2012年第4期388-396,共9页Ighodaro Igbe Eric.K.I. Omogbai Adebayo.O. Oyekan 
Many agents are known to cause qualitative and quantitative differences in intrarenal blood flow. This study tested the hypothesis that angiotensin II (AII) evokes a differential effect on cortical (CBF) and medullary...
关键词:ANGIOTENSIN II HEMODYNAMICS MEDULLARY Blood Flow AT2 Receptors PROSTANOIDS 
COX-mediated endothelium-dependent contractions: from the past to recent discoveries被引量:6
《Acta Pharmacologica Sinica》2010年第9期1095-1102,共8页Michael Sze-Ka WONG Paul Michel VANHOUTTE 
Endothelial cells release various substances to control the tone of the underlying vascular smooth muscle. Nitric oxide (NO) is the best defined endothelium-derived relaxing factor (EDRF). Endothelial cells can al...
关键词:CYCLOOXYGENASE EDCF ENDOTHELIUM gap junctions phospholipase A2 PROSTANOIDS reactive oxygen species TP-receptors 
Is COX-2 a perpetrator or a protector? Selective COX-2 inhibitors remain controversial^1被引量:5
《Acta Pharmacologica Sinica》2005年第8期926-933,共8页Cheng LUO Ming-liang HE Lars BOHLIN 
Aim: COX-2(cyclooxygenase-2) has sparked a surge in pharmaceutical interest since its discovery at the beginning of the 1990s. Several COX-2 selective inhibitors that avoid gastrointestinal side effects have been s...
关键词:COX-2 inhibitor nonsteroidal anti-inflammatory drug PROSTANOIDS cardiovascular disease 
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