supported by generous grants from the National Natural Science Foundation of China(nos.NSFC-21971204,21622203,and 21702161);the Innovation Capability Support Program of Shaanxi Province(no.2020TD-022).
Herein,we report a novel palladium(Pd)-catalyzed asymmetric domino Heck/carbocyclization/Suzuki reaction of N-(2-bromoaryl)-2-naphthylacrylamides.The reaction involves a novel and enantioselective dearomative 1,2-inse...
We are grateful for financial support from the National Natural Science Foundation of China(Nos.21772161 and 21622204);the Natural Science Foundation of Fujian Province of China(No.2019J02001);the President Research Funds from Xiamen University(No.20720180036);NFFTBS(No.J1310024),PCSIRT,and Science&Technology Cooperation Program of Xiamen(No.3502Z20183015).
Summary of main observation and conclusion An efficient copper-catalyzed carbocyclization of silyl enol ether tethered ynamides has been developed,allowing rapid and practical construction of diverse 2-azabicyclo[3.2....
Concise and efficient three-component domino [4+ 1 + 1] carbocyclization to highly substituted fluoren-9-one derivatives promoted by K2CO3 has been developed under microwave irradiation conditions. The direct bis-cy...