supported by the Key Project of Tianjin Natural Science Foundation (No.21JCZDJC01080);the Tianjin Key Medical Discipline (Specialty) (TJYXZDX K-029A);the Academic Backbone of “Clinical Talent Training and Climbing Plan” of Tianjin Medical University and the Tianjin Health Research Project;Science and Technology Development Fund of Nanjing Medical University (NMUB20210180)。
BACKGROUND Chronic renal failure(CRF) patients are predisposed to arrhythmias, while the detailed mechanisms are unclear. We hypothesized the chronic inflammatory state of CRF patients may lead to cardiac sympathetic ...
Supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT),No.NRF-2021R1F1A1064566.
BACKGROUND Inflammatory bowel disease(IBD)is a chronic inflammatory condition of the gastrointestinal tract,with tumor necrosis factor(TNF)-αplaying a key role in its pathogenesis.Etanercept,a decoy receptor for TNF,...
A simple and rapid HPTLC analytical method has been developed and validated for the determination of Etanercept and Filgrastim in pure form and in marketed formulation. Both the drugs were chromatographed on silica ge...
To the Editor:Axial spondyloarthritis(axSpA)is a chronic and progressive disease affecting the spine and sacroiliac(SI)joints,causing inflammatory back pain,stiffness,and inducing new bone formation(syndesmophytes and...
Thanks to Peking University Hong Kong University of Science and Technology Medical Center for providing the research instruments and workplace.
BACKGROUND Cartilage tissue engineering is a promising strategy for treating cartilage damage.Matrix formation by adipose-derived stem cells(ADSCs),which are one type of seed cell used for cartilage tissue engineering...
Supported by National Natural Science Foundation of China,No.81701600.
BACKGROUND Ankylosing spondylitis(AS)is an autoimmune disease characterized by sacroiliitis and spondylitis,with a few hematological abnormalities.Myelodysplastic syndromes(MDS)are a heterogeneous group of hematopoiet...
The research work was carried out using Ultraviolet (UV)—visible spectroscopy and Reverse Phase-Ultra Fast Liquid Chromatography (RP-UFLC) for establishing novel methods for the analysis and quantification of Biosimi...
Psoriasis is a chronic, immune-mediated, inflammatory disease with a high prevalence in the general population (2%). The anti-tumor necrosis factor receptor etanercept is Food and Drug Administration (FDA) approved fo...
Supported by National Natural Science Foundation of China(No.81270999);the Key Project of Miaopu of Fujian Medical University(No.2015MP004);the Qihang Funds of Fujian Medical University(No.2018QH1063)
AIM: To evaluate the effects of etanercept on the expression of Fas, tumor necrosis factor-alpha(TNF-α) and caspase-8 in the early stage of the apoptotic pathway in diabetic rats, and to explore the therapeutic effec...
Supported by National Natural Science Foundation of China (No.91442124; No.81670865)
AIM: To evaluate the safety and efficacy of intravitreal etanercept in the inhibiting of proliferative vitreoretinopathy(PVR) in a model of penetrating ocular injury. METHODS: Penetrating ocular injury on the retina o...