funded by the S&T Program of Hebei(No.21323202D);the Natural Science Interdisciplinary Research Program of Hebei University(No.DXK201913);the Natural Sci-ence Foundation of Hebei Province of China(Nos.H2024201028,H2020201029);the Excellent Youth Research Innovation Team of Hebei University(No.QNTD202406);the Hebei University Research and Innovation Team(No.IT2023C1);the Innovation Capacity Improvement Plan of Hebei Province(No.20567605H);the National Training Program of Innovation and Entrepreneurship for Undergraduates(No.DC2024177)。
Chemical investigation of the marine-derived fungus Chaetomium globosum HBU-45 led to the discovery of chaeglobol A(1).Its structure was determined by spectroscopic analysis,computational electronic circular dichroism...
Steroidal drugs have wide indications such as anti-inflammation, anti-tumor, endocrine regulation,fertility management. Phytosterol is the main starting materials for the industrial synthesis of steroid drugs. Microbi...
Financial support was provided by the Science Foundation for Postdoctoral Program of China(Grant No.2003034251);NCET,and the National Natural Science Foundation of China(NNSFC,Grant No.20432030 and 30400586).We thank Professor K.L.Chen for her help of the fungal material collection.
A new abietane diterpene 12-hydroxy-7-oxo-5, 8, 11, 13-tetraene-18, 6-abietanolide, together with a new natural sterol stigmasta-7, 22-diene-3β, 5α 6α-triol have been isolated from the fruiting body of the fungus P...
A new sterol, ergosta-8(9),22-diene-3,5,6,7-tetraol(3β,5α,6β,7α,22E)(A) together with three known sterols: 3β, 5α,6β-trihydroxyergosta-7,22-diene (B), 3β-hydroxy-5α,8α- epidioxyer-gosta-6,22-diene (C) and er...
Two new sterols were isolated from bulbs of Bolbostemma paniculatum (Maxim.) Franquet. Their structures were elucidated as stigmasta-7, 22, 25-triene-3-O-nonadecanoic acid ester (1) and stigmasta-7, 22, 25-triene-3-O-...
We are grateful to the National Natural Science Foundation of China (No. 29932030) and Natural Science Foundation (No. 970154) of Guangdong Province for financial support for this work.
Cholest-5-en-24-oxo-3, 19-diacetate was synthesized starting from stigmasterol 3 via seven step reactions in 21.0% overall yield. It can be served as a key intermediate for the synthesis of many biologically active 1...
From the aerial parts of Clerodendrum colebrookianum Walp., two new C_29 sterols colebrin A and colebrin B, were isolated, along with a known compound, clerosterol. The structures of the new compounds were elucidated ...
24s-Stigmasta 4,25-diene,3 beta,6 beta-diol 1,a new sterol has been isolated from the algae Laurencia majuscula collected from the south China sea. Its structure was elucidated by spectroscopic methods. Compound 1 was...
A novel and unusual sterol with unsaturation in the△^(5(14)) position,5α-cholesta-8(14),24(25)-diene-3β,6α-diol 1,was isolated from the South China Ses sponge Dysidea sp.The structure and relative stereochemistry ...