FAPESP-2015/26215–9 and CAPES-33002010047P6 to TM.FAPESP-2011/03226–4 to MB;funding bodies had no participation on the study,collection,analysis,interpretation of data nor in writing the manuscript
Background: Insufficient production of anti-luteolytic signals by the pre-attachment embryo is considered a major cause of pregnancy failure in cattle.We tested the hypothesis that transfer of multiple blastocysts(n =...
funded by Fundao de Amparo à Pesquisa do Estado de So Paulo (FAPESP)
Background: Estradiol (E2) is required for luteolysis in cows and its injection stimulates prostaglandin F2α (PGF2α) release. The main goal of our study was to investigate the ability of endometrial explants an...
The recent progress in the studies on the role of local and directed fibrinolysis controlled by plasminogen activators (PAs) and regulated by their inhibitors (PAIs) in reproduction is summarized. Hormone-induced coor...
This minireview summarized our recent studies on the role of plasminogen activator (PA) and inhibitor type-1 (PAI-1) in luteolysis. We have demonstrated that (1) both tissue type and urokinase type plasminogen activat...
Task Foroe for Post-ovulatory Method; Special Programme of Research Development;Research Training in Human Reproduction of the World Health Organization;State Family Planning Commission
Two types of plasminogen activators, tissue type (tPA) and urokinase type(uPA),and a plasminogen activator inhibitor (PAI-1) have been identified in ovariangranulosa cells (GC) of both rat and rhesus monkey. Interacti...
Project supported by HRP,WHO,The State Family Planning commission State Key Laboratory of Reproductive Biology.
It is here reported for the first time that luteal cells are capable of secreting plasminogen activators(PA),(both tissue-type,tPA,and urokinase-type,uPA),and plasminogen activator inhibitor type-1(PAl-1).Using organ...