supported by the National Natural Science Foundation of China,Nos.32100899(to KZL),31830035(to FQX),31771156(to FQX),21921004(to FQX);the National Science and Technology Innovation 2030,No.2021ZD0201003(to FQX);the Key-Area Research and Development Program of Guangdong Province,No.2018B030331001(to FQX);the Strategic Priority Research Program of the Chinese Academy of Sciences,No.XDB32030200(to FQX);the Shenzhen Key Laboratory of Viral Vectors for Biomedicine,No.ZDSYS20200811142401005(to FQX)。
Analyzing the structure and function of the brain's neural network is critical for identifying the working principles of the brain and the mechanisms of brain diseases.Recombinant rabies viral vectors allow for the re...
supported by the National Natural Science Foundation of China,No.81870655(to MBY)。
Successful establishment of reconnection between retinal ganglion cells and retinorecipient regions in the brain is critical to optic nerve regeneration.However,morphological assessments of retinorecipient regions are...
This work was supported by the Spanish Ministry of Economy and Competitiveness,Instituto de Salud Carlos III,Fondo Europeo de Desarrollo Regional“Una manera de hacer Europa”(PI19/00071 to MAB,PID2019-106498GB-I00,RD16/0008/0026 and RD16/0008/0016 to MVS);by the Fundación Seneca,Agencia de Ciencia y Tecnologia Region de Murcia(19881/GERM/15,to MVS).
Techniques to label the neuroretina and the retinal pigment epithelium(RPE)have been the topic of many studies for years.The reliability and reproducibility of these techniques are essential to investigate retinal alt...
supported by the Medical Sciences Foundation of China,No.14CXZ007
Signals from lumbar primary afferent fibers are important for modulating locomotion of the hind-limbs.However,silver impregnation techniques,autoradiography,wheat germ agglutinin-horseradish peroxidase and cholera tox...
supported by a grant from the National Basic Research Program of China(973 Program);No.2011CB707506;the Seed Fund from the Peking University Third Hospital of China,No.YZZ08-9-13;the Linghu Fund from the Peking University Third Hospital of China,No.64508-01
Axonal tracing is useful for detecting optic nerve injury and regeneration,but many commonly used methods cannot be used to observe axoplasmic flow and synaptic transmission in vivo.Manganese(Mn^2+)-enhanced magnet...
supported by a grants from the National Program on Key Basic Research Project(973 Program),No.2014CB542200;the Innovative Research Team by the Ministry of Education,No.IRT1201;the National Natural Science Foundation of China,No.31271284,31171150,81171146,30971526,31040043,31371210,81372044,31471144;the Beijing Municipal Natural Science Foundation of China,No.7142164
The purpose of this study was to investigate the effect of four fluorescent dyes, True Blue(TB), Fluoro-Gold(FG), Fluoro-Ruby(FR), and 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate(Di I...
Totally three articles focusing on magnetic resonance diffusion tensor imaging and diffusion tensor imaging evaluation of ischemic and hemorrhagic stroke, deep brain tumors and healthy corticospinal tract state are pu...
Hunan Province Science and Technology Department Plan,No.2009JT3051
We investigated regeneration of the corticospinal tract and rearrangement of corticospinal nerves after spinal cord injury by biotinylated dextran amine (BDA) nerve tract tracing after neural stem cell transplantati...
the National Natural Science Foundation of China, No. 31070941; 20831006; 30770679
Using neural pathway tracing and immunohistochemical technique, the striato-direct pathway (BDA3 kDa injected into the rat lateral globus pallidus) and striato-indirect pathway (BDA3 kDa injected into the substanti...
This study analyzed migration characteristics of neural stem cells (NSCs) in vitro and in vivo, as well as exogenous gene expression in the brain following transfection of NSCs with an enhanced green fluorescent pro...