National Institutes of Health(NIH):National Heart,Lung,and Blood Institute(NHLBI:R01-HL164772,R01-HL159062,R01-HL146691,T32-HL144456);National Institute of Diabetes and Digestive and Kidney Diseases(NIDDK:R01-DK123259,R01-DK033823);National Center for Advancing Translational Sciences(NCATS:UL1-TR002556-06,UM1-TR004400)(to Gaetano Santulli);Diabetes Action Research and Education Foundation(to Gaetano Santulli);Monique Weill-Caulier and Irma T.Hirschl Trusts(to Gaetano Santulli).
Diabetic cardiomyopathy is a disorder of the cardiac muscle that affects patients with diabetes.The exact mechanisms underlying diabetic cardiomyopathy are mostly unknown,but several factors have been implicated in th...
supported by the Key Science and Technology Research of Henan Province,No.222102310351(to JW);Luoyang 2022 Medical and Health Guiding Science and Technology Plan Project,No.2022057Y(to JY);Henan Medical Science and Technology Research Program Province-Ministry Co-sponsorship,No.SBGJ202002099(to JY)。
Endoplasmic reticulum stress and mitochondrial dysfunction play important roles in Parkinson s disease,but the regulato ry mechanism remains elusive.Prohibitin-2(PHB2)is a newly discove red autophagy receptor in the m...
the Key Research and Development Program of Shaanxi,No.2021SF-227 and No.2020SF-297;the Natural Science Basic Research Program of Shaanxi,No.2023-JC-YB-770。
BACKGROUND Prohibitin 1(PHB1)has been identified as an antiproliferative protein that is highly conserved and ubiquitously expressed,and it participates in a variety of essential cellular functions,including apoptosis...
BACKGROUND The function of prohibitin 1(Phb1)during liver regeneration(LR)remains relatively unexplored.Our previous research identified downregulation of Phb1 in rat liver mitochondria 24 h after 70%partial hepatecto...
funded by the Natural Science Foun dation of Zhejiang Province(No.LY18C190007);the Na tural Science Foundation of China-Zhejiang Joint Fund for the Integration of Industrialization and Informatization(No.U1809212);the Natural Science Foundation of Ningbo City(No.2018A610228);the Scientific and Technical Project of Zhejiang Province(No.2021C02069-1);the Scientific and Technical Project of Ningbo City(No.2021Z002),the Scientific Research Foundation of Ningbo University(No.XYL19023);the Collaborative Innovation Center for Zhejiang Marine High-efficiency and Healthy Aquaculture,the K.C.Wong Magna Fund in Ningbo University.
Mitochondria are important for animals’fertility,and their morphologies and functions during spermatogenesis are un-der investigation.However,the molecular mechanism that regulates the mitochondrial dynamic during sp...